ALFUZOSIN HCL EXTENDED RELEASE

Background and Date of Approval

The U.S. FDA approved Alfuzosin HCL Extended Release for benign prostatic hyperplasia on December 30, 2004. Alfuzosin HCL Extended Release is an alpha-adrenergic antagonist.

Uses

Alfuzosin HCL Extended Release is indicated for its use in treating Benign prostatic hyperplasia, a condition that causes enlargement of the prostate gland in men. The prostate gland is located under the urinary bladder; due to excess growth of the prostate gland, the urethra gets suppressed, leading to uncomfortable symptoms like difficulty in urination.

How is it administered?

Take the tablets in the dose and duration prescribed by your physician. Alfuzosin HCL Extended release should preferably be taken after meals. Swallow the medication whole with a glass of water. Don't break, crush, or chew the tablet.

Side Effects

The most common side effects of Alfuzosin HCL Extended Release are sleepiness, trouble concentrating, dry mouth, dizziness, increase in appetite, drowsiness, and headache. While taking Alfuzosin HCL Extended Release, serious side effects are chest pain and allergic reactions- rashes, swelling, and trouble breathing.

Warnings

Do not take this medicine if you are allergic to Alfuzosin HCL Extended Release or its ingredients. Do not take this medicine if you have liver problems. It is advised that you inform your doctor if you are already taking medicines of the same class, such as their alpha-blockers such as Doxazosin, Indoramin, Prazosin, Terazosin, Tamsulosin, or Phenoxybenzamine to avoid serious complications. Also, if you are taking medication to treat high blood pressure, heart disorders, or fungal infections, report it to your doctor immediately. If you have kidney impairment, birth defects of heartbeat or heart failure, and low blood pressure, talk to your doctor before starting your treatment with Alfuzosin HCL Extended release.

Precautions

If you are above 65 years old and have been prescribed this tablet, be careful while performing your regular activities, as this tablet might make you more sensitive to developing low blood pressure. While using Alfuzosin HCL Extended release, you must notify your doctor about any planned surgical procedures to mitigate the risk of low blood pressure. This is a cancerous condition that commonly affects older men. While on your treatment with this tablet, it is highly unsafe to consume alcohol. Avoid handling machines or driving, as this tablet may cause dizziness and unusual tiredness.

Word of Advice

Follow the dosage and administration instructions provided by your doctor. Inform your doctor of any known allergies or existing medical conditions prior to taking Alfuzosin HCL Extended Release. If you experience unexpected or severe side effects, such as difficulty breathing or signs of allergic reaction, seek immediate medical attention. Inform your healthcare professional of all other medications and supplements you are taking to prevent potential drug interactions. Address any concerns about your treatment with your doctor. Do not exceed the prescribed dose, as overdose may cause hypoglycaemia (low blood sugar).

References

Sanofi, Electronics Medicines Compendium (emc), [ Revised on September 2020] [Accessed on 30th August 2023], https://www.medicines.org.uk/emc/files/pil.1475.pdf Sanofi, U.S FDA, [ Revised on September 2013] [Accessed on August 2023], https://www.accessdata.fda.gov/drugsatfda_docs/label/2014/021287s018lbl.pdf KD Tripathi, Essentials of Medical Pharmacology, Antiadrenergic drugs and drugs for glaucoma, 7th edition, 2013, 142.

Frequently Asked Questions

How can I manage side effects while taking Alfuzosin HCL Extended release?

If you observe any side effects while taking Alfuzosin HCL Extended release, stay hydrated by drinking plenty of fluids. Your medical professional may also recommend over the counter or prescription medications to help manage your symptoms. You should contact your physician if your side effects are severe or persistent.

Are there any dietary restrictions while taking Alfuzosin HCL Extended release?

There are no specific dietary restrictions associated with these medications. However, it is recommended to maintain a healthy and balanced diet to support overall health and well-being.

How long does it take for Alfuzosin HCL Extended release to start working?

The time it takes for the Alfuzosin HCL Extended release to start working varies from person to person. However, it is important to continue taking the medication as your healthcare provider prescribes to achieve optimal treatment outcomes.

How is Alfuzosin HCL Extended release taken?

Alfuzosin HCL Extended release is usually taken orally, with food. It is important to follow the instructions provided by your healthcare provider or the medication's label for the most appropriate administration guidelines.

What are the side effects of Alfuzosin HCL Extended release?

The common side effects of Alfuzosin HCL Extended release are dizziness, painful erection, headache, fatigue, stomach pain, dry mouth, and visual disturbances.

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Written By: Muskan Patel, M.Pharm

Reviewed By: Dr. Vishwa Patel, MBBS