BACILLUS CLAUSII
Background and Date of Approval
Bacillus clausii is a probiotic drug approved by the U.S. Food and Drug Administration and initially indicated for the treatment of diarrhoea.
Uses
Bacillus clausii is used as a treatment for diarrhea, including both acute and chronic diarrhea. It also helps reduce the severity and duration of diarrhea episodes.
How is it administered?
Always take Bacillus clausii exactly as prescribed by your doctor. The chances of stomach upset are less if you take this suspension with food. Oral suspension is prescribed when the patient cannot swallow the tablet form of this medicine. The recommended dose is based on the individualâs body weight. It is important to complete the whole course, even if you start to feel better quickly.
Side Effects
The side effects known to occur commonly during the treatment with Bacillus clausii are rash, itching, swelling around lips and eyes, bloating, and flatulence.
Warnings
Do not take Bacillus clausii if you are allergic to it or any other ingredients listed in the medicine's information. If you have moderate or severe renal impairment and are taking other medications, consult your physician before using the drug. This tablet is not suitable for children under 12 years of age.
Precautions
Individuals with severely compromised immune systems, such as those with HIV/AIDS or undergoing immunosuppressive treatments, should use Bacillus clausii with caution and under the guidance of a healthcare provider. Pregnant and breastfeeding women should consult their physician before using this drug or any other dietary supplement. While probiotics are generally considered safe for most pregnant and breastfeeding women, individual conditions can vary from person to person.
Word of Advice
Diarrhoea can lead to dehydration and fluid loss. It is necessary to drink plenty of fluids, such as water, oral rehydration solutions, or clear broths when using Bacillus clausii to address diarrhoea. Proper hydration helps replace lost fluids and electrolytes and supports the body's recovery.
References
Sanofi, [Revised on Jan 2022], [Accessed on 2nd Sep 2023], https://www.sanofi.in/dam/jcr:f396bc66-49c5-4d15-bd45-91cd2d9a6f6a/Enterogermina%C2%AE%20Oral%20suspension%20PIL.pdf Apurva C Shah et al; Clinical effectiveness of Bacillus clausii and Lactic acid bacillus in acute diarrhea; Indian Journal of Child Health; [Published on 2020]; [Accessed on 2nd Sep 2023]; https://mansapublishers.com/index.php/ijch/article/view/2252 GlaxoSmithKline, US Food and Drug Administration, [Accessed on 2nd Sep 2023], https://www.fda.gov/media/151721/download Bacillus clausii - the probiotic of choice in treating Diarrhea - Longdom. [Accessed on 2nd Sep 2023]; https://www.longdom.org/open-access/bacillus-clausii-the-probiotic-of-choice-in-the-treatment-of-diarrhoea-42348.html KD Tripathi, Essentials of Medical Pharmacology, Drugs for constipation and diarrhea, 7th edition, 2013, 682-683.
Frequently Asked Questions
Is Bacillus clausii safe to take as a supplement?
Bacillus clausii is generally considered safe for most people when used as directed. However, individuals with compromised immune systems or underlying health conditions should consult with a physician before taking any probiotic supplement.
Do I need a prescription for Bacillus clausii supplements?
Bacillus clausii supplements are available over the counter and do not require a prescription. However, it's advisable to consult with a physician before starting any new supplement regimen, especially if you have underlying health conditions or are taking other medications.
Is Bacillus clausii available in different forms?
Bacillus clausii is available in various forms, including capsules, tablets, powders, and liquid formulations. The choice of form may depend on individual preferences and specific medical needs.
Does Bacillus clausii require refrigeration?
Unlike some probiotics, Bacillus clausii is a spore-forming bacterium, which means it can withstand harsh environmental conditions, including temperature variations. Many probiotic products do not require refrigeration but should be stored according to the manufacturer's instructions.
Can Bacillus clausii be used for children and infants?
Bacillus clausii is sometimes recommended for children and infants, but the dosage and usage instructions should be followed carefully, as they can vary by age and product. Consult a pediatrician for guidance on using this drug for children.