BENFOTIAMINE,METHYLCOBOLAMIN,ALPHA LIPOIC ACID,FOLIC ACID
Background and Date of Approval
Benfotiamine, methylcobalamin, alpha lipoic acid, folic acid
Uses
Benfotiamine + methylcobalamin + alpha lipoic acid + folic acid combination is approved for medical use as a nutritional supplement in India to treat nutritional deficiency and to manage diabetic neuropathy.
How is it administered?
Benfotiamine + methylcobalamin + alpha lipoic acid + folic acid offer diverse health benefits. They are used to treat nutritional deficiencies and nerve disorders. Benfotiamine, a fat-soluble vitamin B1, is vital for nerve health, especially in conditions like diabetic neuropathy. Methylcobalamin, an active B12 form, is crucial in managing anemia and nerve-related issues. Alpha-lipoic acid acts as an antioxidant and is beneficial for diabetic neuropathy and metabolic syndrome. Folic acid, a synthetic form of vitamin B9, helps prevent neural tube defects during pregnancy and aids in treating anemia caused by folate deficiency.
Side Effects
Benfotiamine + methylcobalamin + alpha lipoic acid + folic acid combination is available in tablet form for oral intake. Your physician will decide the dosage of this injection based on the severity of your disease and other factors.
Warnings
Benfotiamine + methylcobalamin + alpha lipoic acid + folic acid supplement is generally safe to consume and is not associated with significant side effects. However, some people may experience side effects such as nausea, vomiting, diarrhea, stomach upset, and headache. If you experience any side effects, talk to your doctor.
Precautions
This combination is not recommended for people who are allergic to any of its active ingredients. Inform your doctor if you have kidney disease, liver disease, or kidney stones before taking these supplements. Always give a detailed account of your medical history and the medications before taking this supplement.
Word of Advice
Healthcare professionals should be consulted before use, particularly for patients who are pregnant, breastfeeding, or have underlying health conditions including liver disease, lung disease, heart disease, or kidney disease. Patients consuming alcohol should seek medical advice before taking this supplement combination. Benfotiamine + methylcobalamin + alpha-lipoic acid + folic acid should be consumed with food to minimise the risk of stomach upset. Adherence to the dosage specified by your healthcare provider is essential. Prior to initiating this supplement, inform your doctor of all other medications and supplements currently being taken to ensure compatibility. Should any side effects occur, contact your doctor promptly for guidance.
References
Wörwag Pharma, Manufacturer, [Revised on Oct 2021] [Accessed on Oct 2023] https://www.ravimiregister.ee/Data/PIL_ENG/PIL_14350_ENG.pdf Viswanathan M, et al., Folic Acid Supplementation to Prevent Neural Tube Defects: Updated Evidence Report and Systematic Review for the US Preventive Services Task Force; JAMA. [Revised on Aug 2023] [Accessed on Oct 2023] https://pubmed.ncbi.nlm.nih.gov/37526714/ Miao Y, et al., The effect of B-vitamins on the prevention and treatment of cardiovascular diseases: a systematic review and meta-analysis; Nutr Rev; [Revised on Oct 2023] [Accessed on Oct 2023] https://pubmed.ncbi.nlm.nih.gov/37850302/ Muley A, et al., Effect of thiamine supplementation on glycaemic outcomes in adults with type 2 diabetes: a systematic review and meta-analysis; BMJ Open; [Revised on Aug 2022] [Accessed on Oct 2023] https://pubmed.ncbi.nlm.nih.gov/36008064/ Temova Rakuša Ž, et al., Vitamin B12 in Foods, Food Supplements, and Medicines-A Review of Its Role and Properties with a Focus on Its Stability; Molecules ; [Revised on Dec 2022] [Accessed on Oct 2023] https://pubmed.ncbi.nlm.nih.gov/36615431/ Nguyen H, et al., Alpha-Lipoic Acid; Treasure Island (FL): StatPearls Publishing; [Revised 2022 Sep 26] [Accessed on Oct 2023] https://www.ncbi.nlm.nih.gov/books/NBK564301/
Frequently Asked Questions
What is the difference between benfotiamine and thiamine?
Benfotiamine is a fat-soluble form of thiamine (vitamin B1) absorbed much more efficiently than water-soluble thiamine salts.
What is the difference between methylcobalamin and cyanocobalamin?
Methylcobalamin is a natural, active form of vitamin B12 that can be utilized directly by the body. In contrast, cyanocobalamin is a synthetic form of vitamin B12 that needs to be converted into methylcobalamin by the body before it can be utilized.
What is alpha lipoic acid?
Alpha lipoic acid is an antioxidant that helps to protect the body from damage caused by free radicals. It also helps to improve blood sugar control and nerve function.
What is folic acid?
Folic acid is a synthetic form of vitamin B9 that helps the body make new cells. It is especially important for pregnant women, as it helps to prevent congenital disabilities.
What is the use of benfotiamine + methylcobalamin + alpha-lipoic acid + folic acid combination tablet?
Benfotiamine + methylcobalamin + alpha-lipoic acid + folic acid combination tablet is prescribed for various conditions, including diabetic neuropathy, to manage nerve damage resulting from diabetes, nerve disorders, and deficiencies in essential vitamins B1, B9, and B12. It is also used to address metabolic syndrome, act as a preventive measure, and treat anemia caused by vitamin deficiencies. Benfotabs is a comprehensive solution for these health issues, providing essential nutrients and support to the body.
Can I take benfotiamine + methylcobalamin + alpha-lipoic acid + folic acid combination tablet if I am pregnant or breastfeeding?
Yes, the combination of benfotiamine + methylcobalamin + alpha-lipoic acid + folic acid should be taken during pregnancy or breastfeeding solely under medical guidance. Inform your doctor if you are breastfeeding before using this combination.