BENZYLPENICILLIN

Benzylpenicillin was approved for medical use in the 1940s and was added to the World Health Organization's List of Essential Medicines for the treatment of specific bacterial infections.

Benzylpenicillin is a narrow-spectrum antibiotic used to treat various types of bacterial infections such as septicemia, meningitis, pericarditis, severe pneumonia and diphtheria.

Benzyl penicillin is available as an injection with the strength of 500000IU Injection for intramuscular use only (injected directly into your muscle). Your physician will decide the correct dosage and duration based on age, body weight, and disease condition.

Serious side effects of benzyl penicillin may include anaphylactic shock, characterized by severe allergic reactions such as itching, flushed or pale skin, a rapid pulse, stomach upset, and fainting. On a more common note, individuals taking benzyl penicillin may experience fungal infections, diarrhea, nausea, and changes in certain medical test results. It's important to be vigilant for signs of anaphylactic shock and promptly seek medical attention if observed.

It is not recommended to take benzathine penicillin if you are allergic to penicillin or other antibiotics. You need to inform your physician if you have liver disorders, kidney disorders, asthma, or if you are allergic to peanuts or soya before taking a benzathine penicillin injection. Before starting this treatment, give a detailed overview of your medical history and current medications.

When using benzyl penicillin, exercise caution and inform your doctor if you are pregnant, as its safety is determined after weighing the benefits and risks. Avoid breastfeeding during treatment and inform your doctor about any lung diseases or severe liver disorders. Alcohol interaction may alter its therapeutic effect, and it is advised to avoid driving due to the potential serious side effects. Consult your doctor for personalized guidance on these precautions.

Take benzylpenicillin exactly as prescribed for your bacterial infection to reduce the risk of drug resistance. Skipped doses may reduce treatment effectiveness. Complete the entire course of treatment even after symptoms improve. Include probiotic-rich foods and high-fibre foods to help maintain healthy gut bacteria. Avoid calcium-rich foods, grapefruit, and alcohol while taking this medicine. Inform your healthcare provider about benzylpenicillin treatment before any diagnostic tests, as it may affect liver function tests and prothrombin time results.

Genus Pharmaceuticals, Electronic Medicines Compendium (EMC), [Revised on Aug 2021] [Accessed on 28th Sep 2023], https://www.medicines.org.uk/emc/product/3828/pil Pfizer, US Food and Drug Administration, [Revised on April 2019], [Accessed on 28th Sep 2023], https://www.accessdata.fda.gov/drugsatfda_docs/label/2019/050141s237lbl.pdf KD Tripathi, Essentials of Medical Pharmacology, Beta-lactam antibiotics, 7th edition, 2013, 717.