BETA 1,3/1,6 D-GLUCAN

Beta 1,3/1,6 D-Glucan is approved and recognised for its immunomodulatory potential, with the capacity to influence and regulate immune system function. Beta 1,3/1,6-D-glucan is a polysaccharide—a complex carbohydrate—extracted from the cell walls of certain fungi, including yeast and mushroom species.

Beta 1,3/1,6 D-Glucan is often used as dietary supplement or nutraceutical in the prevention and treatment of infections; it is also used to enhance immune response in people with a weak immune system (children, athletes, aged population).

Beta 1,3/1,6 D-Glucan is available in a capsule dosage form for oral use. Your physician will decide the correct dosage and duration based on age, body weight, and disease condition.

Like any other drug, beta 1,3/1,6-D-glucan also has some side effects. The most common side effects people may experience are allergic reactions (such as bruising, pain, redness, swelling, and itching), nausea, bloating and digestive discomfort. Keep an eye out for these signs and contact your doctor immediately if you experience any of them while receiving therapy.

It is not recommended to take this medication if you are allergic to the active substance Beta 1,3/1,6 D- glucan and its components. Immune system activation is the main targeted effect of beta 1,3/1,6-D-glucan. Even though this is frequently desired, people who take immunosuppressive drugs or have autoimmune diseases should speak with a doctor before using these supplements. People who use blood sugar-lowering drugs or have diabetes should constantly check their blood sugar levels and speak with a healthcare provider. Tell your physician about all the medications you have been taking recently before starting treatment.

There is insufficient information on the safety of Beta 1,3/1,6-D-glucan supplements for children, expectant mothers, and nursing mothers. These populations should speak with a healthcare provider before taking any of these supplements. It is really important to be safe, so make sure you discuss any concerns you may have with your healthcare professional.

Individuals with known allergies to the source materials of beta-1,3/1,6-D-glucan, such as mushrooms or yeast, should exercise caution and avoid products derived from those sources. Consultation with a healthcare professional is recommended for people with autoimmune conditions, those taking other medications, and women who are pregnant or breastfeeding, as beta-glucans may interact with certain medicines or affect individual health conditions. Patients should monitor for any digestive discomfort and use the supplement according to the recommended dosage. Selecting products from reputable manufacturers with appropriate quality-control standards is also advisable. Since individual responses to beta-glucans may vary, patients should discuss their health status and specific needs with a healthcare provider to receive appropriate and personalized guidance.

Elena De Marco Castro, Philip C. Calder, and Helen M. Roche, 𝜷-1,3/1,6-Glucans and Immunity: State of the Art and Future Directions, Mol. Nutr. Food Res. 2021, 65, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7816268/pdf/MNFR-65-1901071.pdf