BIFIDOBACTERIUM,LACTOBACIILLUS,OXALOBACTER

Background and Date of Approval

Bifidobacterium + Lactobacillus + Oxalobacter is indicated for the management of calcium oxalate kidney stones, hyperoxaluria, oxalosis, and maintenance of gut health.

Uses

Bifidobacterium + Lactobacillus + Oxalobacter is used in people with calcium oxalate kidney stones, hyperoxaluria (high levels of oxalate in the urine), or oxalosis. It may also prevent kidney stones from forming in people with a history of kidney stones.

How is it administered?

Bifidobacterium + Lactobacillus + Oxalobacter is an orally administered medication. However, the dosage may vary depending on your individual needs. Be sure to follow your doctor's instructions carefully.

Side Effects

The most common side effects of Bifidobacterium + Lactobacillus + Oxalobacter include gas, bloating, and diarrhea. Serious side effects from this medication are rare, but they can include allergic reactions, infection, and sepsis (a life-threatening condition caused by an overwhelming infection).

Warnings

Bifidobacterium + Lactobacillus + Oxalobacter may cause an allergic reaction in some people. Symptoms of an allergic reaction can include hives, swelling of the face, lips, tongue, or throat, difficulty breathing, and dizziness. It contains live bacteria, which can potentially cause infection in some people. This is especially true for people with a weakened immune system, such as HIV/AIDS or cancer. It may increase the risk of sepsis in some people.

Precautions

If you experience symptoms like hives, swelling of the face, lips, tongue, or throat, difficulty breathing, and dizziness after taking Bifidobacterium + Lactobacillus + Oxalobacter, stop taking the medication and seek medical attention immediately. If you experience any signs or symptoms of infection, such as fever, chills, body aches, or cough, stop taking this medication and see a doctor immediately. If you experience any signs or symptoms of sepsis, such as high fever, confusion, low blood pressure, or rapid breathing, seek medical attention immediately.

Word of Advice

Consult your doctor before taking Bifidobacterium + Lactobacillus + Oxalobacter, particularly if you have any existing health conditions or are on other medications. Do not use this medication if you are allergic to any of its ingredients. Avoid this medication if you have severe gastrointestinal disorder, including inflammatory bowel disease or pancreatitis. Do not use this medication if you are immunosuppressed. Exercise caution when using this medication during pregnancy and breastfeeding. Take this medication with food or water to minimise the risk of stomach upset. Store at room temperature, protected from moisture and heat. Keep this medication out of reach of children. Inform your doctor of all medications you are taking before starting this medication.

References

Silvia Turroni et al; Oxalate-Degrading Activity in Bifidobacterium animalis subsp. lactis: Impact of Acidic Conditions on the Transcriptional Levels of the Oxalyl Coenzyme A (CoA) Decarboxylase and Formyl-CoA Transferase Genes; Applied and Environmental Microbiology; [Published on 2nd July 2010] [Accessed on 30th Sept/2023] https://www.ncbi.nlm.nih.gov/pubmed/20601517 Roswith Siener et al.; The role of Oxalobacter formigenes colonization in calcium oxalate stone disease; Kidney International; [Published on June 2013] [Accessed on 30th Sept/2023] https://pubmed.ncbi.nlm.nih.gov/23536130/ Pragasam Viswanathan: Probiotics Supplements for the Management of Calcium Oxalate Kidney Stones- Are We Ready for it?; Journal of Kidney; [Published on 23rd April 2018] [Accessed on 30th Sept 2023]; https://www.longdom.org/open-access/probiotics-supplements-for-the-management-of-calcium-oxalate-kidney-stonesare-we-ready-for-it-2472-1220-1000e112.pdf Kumar R et al.; Role of Oxalobacter formigenes in Calcium Oxalate Stone Disease: A Study from North India; European Urology; [Published on 1st March 2002] [ Accessed on 30th Sept 2023] https://www.europeanurology.com/article/S0302-2838(02)00040-4/fulltext

Frequently Asked Questions

What are the side effects of Bifidobacterium + Lactobacillus + Oxalobacter?

Bifidobacterium + Lactobacillus + Oxalobacter is generally well-tolerated. However, some people may experience mild side effects such as gas, bloating, and diarrhea. These side effects are usually mild and temporary.

How long should I take Bifidobacterium + Lactobacillus + Oxalobacter?

Your doctor will advise you on how long to take Bifidobacterium + Lactobacillus + Oxalobacter. For most people, taking Bifidobacterium + Lactobacillus + Oxalobacter for at least 6 months is recommended. However, some people may need to take it for longer.

Is Bifidobacterium + Lactobacillus + Oxalobacter available over the counter?

No, Bifidobacterium + Lactobacillus + Oxalobacter is not available over the counter. It is a prescription medication that is only available from a doctor.

Is Bifidobacterium + Lactobacillus + Oxalobacter a cure for kidney stones?

No, Bifidobacterium + Lactobacillus + Oxalobacter is not a cure for kidney stones. However, it can help prevent kidney stones from forming and reduce the risk of recurrent kidney stones.

How long does it take for Bifidobacterium + Lactobacillus + Oxalobacter to work?

It may take several weeks or even months to see the full effects of Bifidobacterium + Lactobacillus + Oxalobacter. This is because it takes time for the probiotic bacteria to colonize the gut and lower oxalate levels.

What should I do if I miss a Bifidobacterium + Lactobacillus + Oxalobacter dose?

If you miss a Bifidobacterium + Lactobacillus + Oxalobacter dose, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Refrain from double up on doses to make up for a missed dose.

Written By: Muskan Patel, M.Pharm

Reviewed By: Dr. Vishwa Patel, MBBS