BISOPROLOL

Bisoprolol is an antihypertensive medicine that belongs to the class of beta1-selective adrenoceptor-blocking agents. It received U.S. FDA approval in 1986 for the treatment of hypertension, angina pectoris, and chronic heart failure.

Bisoprolol has been approved to treat hypertension (high blood pressure), angina pectoris (chest pain), and chronic heart failure.

The recommended initial dose of Bisoprolol is 5mg per day. The usual dosage is 10 mg once daily, with a maximum daily dose of 20 mg. Follow your doctor's instructions exactly. It should be taken in the morning with food. Swallow the tablets as a whole with water. Do not crush, chew or break it.

The common side effects that are likely to occur while you are on the treatment with Bisoprolol are dizziness, nausea, vomiting, diarrhea, constipation, headache, bradycardia, asthenia, fatigue, hypotension, coldness, or numbness in the extremities. Inform your healthcare professional if these side effects disturb you or persist. Report to your doctor immediately if you have a slow heart rate, worsening of heart failure (increased breathlessness and swelling of legs), dizziness, weakness, breathing difficulty, and allergic reaction like swelling of the face, mouth, or throat and muscle coordination problems.

Contact your physician immediately if you experience allergies to Bisoprolol and its ingredients. Inform your physician if you have kidney or liver conditions. While taking this medicine, your doctor monitors blood pressure levels. Before taking this medication, let your medical professional know if you have a medical history of severe asthma or chronic lung disease, slow or irregular heart rate, heart failure, cardiogenic shock, metabolic acidosis, or untreated pheochromocytoma.

Consult your doctor before using this medication if you are pregnant or planning to have a baby. Bisoprolol tablets should not be taken while pregnant unless specifically advised by your doctor. If this medication is required in pregnancy, the uteroplacental blood flow and fetal growth should be closely monitored. Avoid breastfeeding your baby while on the treatment, as it is not known whether Bisoprolol passes into the breastmilk and affects the baby.

Regular blood pressure monitoring is necessary to prevent hypotension. If syncope or dizziness upon sudden position change has occurred, physician evaluation is required prior to commencing therapy. Dose discontinuation without medical guidance may result in elevated blood pressure and increased risk of myocardial infarction.

KD Tripathi, Essentials of Medical Pharmacology, Cardiac glycosides and Drugs for heart failure, 7th Edition, 2013, 523-526. Duramed Pharmaceuticals Inc., US Food and Drug Administration, [ Revised on May 2007] [ Accessed on 2 nd November 2022], https://www.accessdata.fda.gov/drugsatfda_docs/label/2007/019982s014lbl.pdf Accord Healthcare Limited; Electronic Medicines Compendium (EMC), [Revised on January 2022] [Accessed on 2 nd November 2022], https://www.medicines.org.uk/emc/product/6126/smpc#gref