CALCIUM CHLORIDE
Background and Date of Approval
The U.S. FDA approved calcium chloride on 28 January 2000. Calcium chloride is a mineral salt. This medication is used to increase blood calcium levels in the body and restore normal cardiac function during cardiac arrest when potassium levels are extremely elevated.
Uses
Calcium chloride is used as a part of the Cardiopulmonary resuscitation procedure (CPR) to rescue people from cardiac arrest, and it is used to treat low calcium levels.
How is it administered?
This medicine is given only in a hospital setup by a healthcare provider. Calcium chloride will be given to you by your doctor. It is given intravenously (into a vein), either as single injections or as a continuous infusion (a drip). Your physician will decide the dosage and frequency of this injection based on the severity of your disease and other factors.
Side Effects
The common side effects that are experienced while you are on the treatment with Calcium chloride are chalky taste in the mouth, hot flushes, lowered blood pressure, loss of appetite, nausea, vomiting, constipation, stomach pain, weakness, mental disturbances, extreme thirst, increased urination, bone pain, kidney calcium deposits, kidney stones, irregular heartbeat, coma, and even the formation of blood clots in veins, as well as the possibility of elevated blood pressure.
Warnings
Inform your doctor if you are allergic to calcium salts or any of the ingredients present in them, heart problems, kidney problems that result in low calcium levels, excess calcium in blood or urine, breathing problems, or dangerously fast heartbeat (ventricular fibrillation), high levels of vitamin D (sarcoidosis) and kidney stones. Consult your doctor if you have breathing problems or a dangerously fast heartbeat (ventricular fibrillation). It is not recommended in treating asystole (heart to stop pumping) and electromechanical dissociation (Pulseless electrical activity of the heart).
Precautions
Inform your doctor if you have a local âburningâ sensation and symptoms of low blood pressure (dizziness, weakness, nausea, or blurry vision) because this medicine may cause a drop in the blood pressure level. Consult your doctor if you are planning to get pregnant or think you may be pregnant or while you are breastfeeding. Elderly patients with liver, kidney, and heart should be cautious while taking the medicine.
Word of Advice
Inform your healthcare provider if you are taking medications such as digitoxin for heart conditions, tetracyclines for bacterial infections, or thiazide diuretics such as indapamide for blood pressure and fluid retention. Also, disclose any history of bone disorders, including Paget’s disease. Seek medical advice if you experience breathing difficulties or have an underlying lung condition, as regular monitoring of electrolyte levels, particularly calcium, may be recommended. Since the medication may cause a decrease in blood pressure, blood pressure should be checked before treatment and monitored as advised. Patients with kidney impairment should use the medication cautiously because its aluminum content may affect kidney function.
References
Aurum Pharmaceuticals Ltd, Electronic Medicines Compendium (EMC), [Revised on Jan 2018] [Accessed on 28th Sep 2023], https://www.medicines.org.uk/emc/files/pil.4126.pdf Hospira Healthcare Corporation, US Food and Drug Administration, [Revised on April 2017], [Accessed on 28th Sep 2023], https://www.accessdata.fda.gov/drugsatfda_docs/label/2018/021117s015lbl.pdf
Frequently Asked Questions
Can I drink alcohol while taking Calcium chloride?
No, it is not recommended to drink alcohol when you are under treatment. It may cause undesirable side effects. So, it is advised to consult your doctor.
Can I take Calcium chloride if I have a history of allergies?
Inform your doctor that you are allergic to calcium chloride before starting medicine.
Is Calcium chloride used in CPR?
Yes, it is used as a part of CPR (Cardiopulmonary resuscitation) procedures after cardiac arrest to restore the heartbeat.
Can I take calcium chloride if I have kidney problems?
No, it is not recommended to take calcium chloride for kidney patients. Inform your doctor if you have a history of kidney disorder.
Is there a specific monitoring schedule or tests I must undergo while taking Calcium chloride?
You may be advised to monitor your electrolyte level (calcium) regularly. There is a risk of a drop in the blood pressure as a side effect. So, it is recommended to monitor your blood pressure before treatment.