CARBOPROST TROMETHAMINE

Carboprost tromethamine, a synthetic prostaglandin, received U.S. FDA approval in 2019. The medication is indicated for treatment of postpartum haemorrhage resulting from uterine atony (loss of uterine muscle tone following childbirth) in women. Administration is not self-directed; dosage determination and ongoing health monitoring remain the responsibility of the treating physician, who will assess individual patient circumstances and medical history.

Carboprost tromethamine is used for postpartum hemorrhage (stop the excessive bleeding in women who have just given birth)

Inform your doctor about any prescribed medications, over-the-counter medicines, nutritional or vitamin supplements, and herbal products you take or have taken before the treatment. Certain medications may interact with carboprost tromethamine and can cause undesirable side effects.

The common side effects that are experienced while you are on the treatment with Carboprost tromethamine diarrhea, nausea, vomiting, increased body temperature, headache, flushing, hot flushes, chills, cough, uterine bleeding, and potential complications such as retained placenta or membranes, as well as endometritis.

Consult your doctor if you are allergic to carboprost tromethamine or any ingredients, and inform your doctor if you have acute pelvic inflammatory disease. Consult your doctor if you are planning to get pregnant or think you may be pregnant or while breastfeeding because it is contraindicated for pregnant women.

The safety and effectiveness of children and the elderly are not established. They are also contraindicated for patients with heart, liver, lung, and kidney problems, diabetes, jaundice, anemia, problems in blood pressure, and epilepsy.

Inform your doctor if you are taking carboprost tromethamine alongside any prescription or non-prescription medicines. As this drug may exacerbate cardio-pulmonary problems, your doctor will monitor your health status and provide supplemental oxygen if necessary. Patients with a history of allergic reactions should disclose this to their doctor.

Pfizer Limited, Electronic Medicines Compendium (EMC), [Revised on May 2022] [Accessed on 7 Oct 2023], https://www.medicines.org.uk/emc/product/3828/pil Pfizer, US Food and Drug Administration, [Revised on Dec 2013], [Accessed on 28th Sep 2023], https://www.accessdata.fda.gov/drugsatfda_docs/label/2019/050141s237lbl.pdf KD Tripathi, Essentials of Medical Pharmacology, Prostaglandins, Leukotrienes and Platelet activating factor, 7th edition, 2013, 189.