CEFIXIME,POTASSIUM CLAVULANATE
Background and Date of Approval
The combination of Cefixime and Potassium Clavulanate received approval from the U.S. Food and Drug Administration (FDA) in 1989.
Uses
Cefixime + Potassium clavulanate is indicated to treat bacterial infections of the nose, ear, throat, chest, lungs, urinary tract, and uncomplicated gonorrhea.
How is it administered?
Tablet: Take the prescribed dose of Cefixime + Potassium clavulanate tablet by using the measuring cup or dosing syringe, or the dropper provided by the pack. Shake the pack well before each use. Syrup: Take the prescribed dose of Cefixime + Potassium clavulanate syrup by using the measuring cup or dosing syringe, or the dropper provided by the pack. Shake the pack well before each use.
Side Effects
The side effects known to occur commonly during the treatment with Cefixime + Potassium clavulanate are nausea, stomach pain, diarrhea, indigestion (dyspepsia), headache, dizziness, flatulence (accumulation of gas), and itching.
Warnings
Report to your physician immediately if you experience allergic reactions to Cefixime + Potassium clavulanate, other cephalosporin antibiotics, or any of the other ingredients of this medicine. Tell your doctor before treatment commencement with this medication if you have kidney or liver disease.
Precautions
Consult your doctor before using this medication if you are pregnant or plan to have a baby. Cefixime + Potassium clavulanate should not be taken while pregnant unless specifically advised by your doctor. Avoid breastfeeding your baby while on the treatment with this medication. It is unknown if this medicine passes into the breast milk.
Word of Advice
Do not discontinue this medication without medical guidance. Consult your doctor before stopping treatment, as premature cessation may allow the infection to progress and become more difficult to treat. Avoid driving or operating machinery, as this medication may cause confusion and drowsiness.
References
KD Tripathi, Essentials of Medical Pharmacology, Beta-lactam antibiotics, 7th Edition, 2013, 726-728. Lupin Limited; US Food & Drug Administration, [Revised on May 2012], [Accessed on 13/05/2023 ], https://www.accessdata.fda.gov/drugsatfda_docs/label/2012/203195s000lbl.pdf Sanofi., Electronic medicines compendium (EMC), [Revised on April 2022] [Accessed on 13/05/2023 ], https://www.medicines.org.uk/emc/files/pil.5534.pdf Shelly Rainforth Collins; Clavulanate Potassium; Accessed on 13/05/2023; https://www.sciencedirect.com/topics/medicine-and-dentistry/clavulanate-potassium
Frequently Asked Questions
Can children use Cefixime + Potassium clavulanate?
No, Cefixime + Potassium clavulanate is not recommended for children under the age of 10.
What are the uses of Cefixime + Potassium clavulanate?
Cefixime + Potassium clavulanate is used for bacterial infections of the nose, sinuses (sinusitis), ear, throat, chest, lungs, and urinary tract.
Can Cefixime + Potassium clavulanate cause diarrhea?
Yes, Cefixime + Potassium clavulanate can cause diarrhea, a sign of a new infection. If you have watery or bloody diarrhea, consult your doctor.
Who should not take Cefixime + Potassium clavulanate?
Patients who have experienced allergic reactions (hypersensitivity) to Cefixime + Potassium clavulanate or have colitis, renal dysfunction, or liver disease should not use this medicine.
Can I stop taking Cefixime + Potassium clavulanate if I feel better?
No, even if you feel better, keep taking Cefixime + Potassium clavulanate + Potassium clavulanate until the end of the treatment. Do not withdraw (stop) this medication without consulting your physician because the infection may come back or worsen.