CEFTRIAXONE,TAZOBACTAM
Background and Date of Approval
Ceftriaxone + tazobactam is approved for medical use in treating bacterial infections, including those of the respiratory tract, urinary tract, skin, bone, and joints.
Uses
Ceftriaxone + tazobactam treats bacterial infections. It is used for treating lower respiratory tract infections and community, pneumonia, acute bacterial otitis media, skin infections, urinary tract infections, uncomplicated gonorrhea, pelvic inflammatory disease, bacterial septicemia, bone and joint infections, intra-abdominal infections, bacterial meningitis. It is also used in peri-operative prophylaxis to treat the infection associated with surgery.
How is it administered?
Ceftriaxone + tazobactam is available as a 1.125gm injection. Your physician will decide the correct dosage and duration based on age, body weight, and disease condition. Only stop taking the tablet if your doctor advises you to stop.
Side Effects
The common side effects that are experienced while you are on the treatment with ceftriaxone + tazobactam are diarrhea, constipation, nausea, abnormalities in white blood cells, changes in liver functions, and rash. Consult your doctor immediately if you feel any allergic reaction (Sudden swelling of the face, throat, lips, or mouth).
Warnings
Inform your doctor if you have a gastrointestinal disorder before using the medicine. You will be recommended to monitor the prothrombin time if you have a patient with a hepatic disorder or malnutrition. Children with hyperbilirubinemia should be cautious before using the medicine.
Precautions
Children with hyperbilirubinemia should be cautious before using the medicine. Consult your doctor if you are planning to get pregnant or think you may be pregnant while breastfeeding. Ceftriaxone + tazobactam tablets are contraindicated to pregnant women and harmful to the unborn female baby. It is recommended to consult your doctor if you have any kidney or liver impairment before administering the medicine.
Word of Advice
Your doctor will recommend monitoring your liver function and blood count to prevent complications associated with this medicine. Maintain adequate hydration and take electrolytes to compensate for fluid loss during diarrhoea. Avoid consuming junk foods, which may worsen nausea.
References
Biocon Limited, Manufacturer, [ Accessed on Nov 2023], http://www.biocon.com/docs/prescribing_information/ccd/supravatz_pi.pdf Wockhardt UK Ltd, Electronic medicines compendium (EMC), [Revised on June 2022] [Accessed on Nov 2023], https://www.medicines.org.uk/emc/files/pil.1361.pdf Pfizer, Inc., US Food and Drug Administration, [Revised on April 2022], [Accessed on Nov 2023], label (fda.gov)
Frequently Asked Questions
What precautions should I take while on ceftriaxone + tazobactam?
Be aware of any potential infections that could come up and consult your doctor. Your doctor will advise you to check the blood and liver function tests. Let them know if you're having any new or worse symptoms immediately.
Can I use ceftriaxone + tazobactam if I have liver problems?
Inform your physician about any underlying liver disorders before taking ceftriaxone + tazobactam, as this medication should be used cautiously in liver disease patients.
Is it safe to use ceftriaxone + tazobactam for children?
Children with hyperbilirubinemia should be cautious before using the medicine. So, it is recommended to consult your doctor before using ceftriaxone + tazobactam.
Can I use ceftriaxone + tazobactam if I have kidney problems?
Inform your doctor if you have kidney problems before using the medicine.
Is ceftriaxone + tazobactam causing diarrhea?
Yes, you may experience diarrhea while under medication. Drink enough water and take electrolytes to overcome water loss during diarrhea.