CILNIDIPINE,TELMISARTAN

Background and Date of Approval

Telmisartan+cilnidipine is an antihypertensive drug. This combination has two active ingredients. Telmisartan belongs to the group of medications called angiotensin II receptor antagonists. Cilnidipine belongs to the class of medications called calcium channel blockers. The initial FDA approval was in 1998 for its medical uses.

Uses

It is used to treat high blood pressure. It helps relax the blood vessels by making it easier for the heart to pump blood all over the body, lowering the risk of heart attack and stroke.

How is it administered?

This medication is taken as per the advice of the doctor. It can be taken on an empty stomach or with food, but it has to be taken at the same time daily. It’s very important to take this medicine even if you feel well. As it causes ankle swelling, sitting by raising the leg upward is better. The dosage of this medication will depend upon the condition and how individuals respond to the medication. Avoid breaking or chewing the tablet. Instead, swallow it whole with a glass of water

Side Effects

The common side effects of telmisartan + cilnidipine are fever, increased potassium level, tiredness, feeling sleepy, headaches, back pain, difficulty breathing, stomach upset, nausea, and muscle pain. Other serious side effects are swelling of ankles and feet, dizziness, vision change, and palpitation.

Warnings

Inform the doctor about any kidney or liver-related problems. If patients are breastfeeding mothers or planning for pregnancy, they must inform the doctor before starting this medication. While using this medication, blood pressure should be monitored regularly, and a kidney function test should be performed to note if there are any abnormal changes.

Precautions

This medication is taken as per the advice of the doctor. It can be taken on an empty stomach or with food, but it must be taken at a fixed time daily. It's very important to take this medicine even if you feel well. The dosage of this medication will depend upon the condition and how individuals respond to the medication. It acts by lowering blood pressure and reduces the risk of heart attack and stroke, so don't stop this medication without the proper advice of a doctor. Inform your doctor about any medicines that you are taking or have taken before, including prescription, over-the-counter, nutritional or vitamin supplements, and herbal products. Certain medications may interact with telmisartan + cilnidipine and cause undesirable side effects.

Word of Advice

Store away from light and moisture. Maintain temperature below 30°C. Keep telmisartan and cilnidipine out of sight and reach of children and pets. If you miss a dose, take your next dose at the scheduled time. Do not take a double dose to compensate for a missed dose. Inform your doctor if you have any history of allergic reactions to avoid life-threatening complications. Inform your doctor before starting treatment if you are pregnant or have liver, kidney, or uterine problems. During treatment with this medication, blood pressure should be monitored regularly, and kidney function tests should be performed to check for any abnormal changes.

References

KD. Tripathi. Antianginal and other Anti-ischaemic Drugs & Drugs Affecting Renin-Angiotensin System. Eighth edition. June 2018. Page – 596 & 536. https://www.torrentian.com/pisheet/Upload/PI_Sheet/2909.pdf . Torrent Pharmaceuticals Ltd. Telsar N (Telmisartan and Cilnidipine Tablets). [Revised in April 2020] [Accessed on 29/10/2022] https://www.accessdata.fda.gov/drugsatfda_docs/label/2004/020850s011lbl.pdf (revised on 3/5/2011) (accessed on 29/10/2022)

Frequently Asked Questions

How can I know my potassium level is high while taking Telmisartan+cilnidipine?

The doctor will be monitoring the potassium level in the blood. Patients should avoid potassium supplements and a diet rich in potassium to prevent the side effects caused by this medication.

Is Telmisartan+cilnidipine blood thinner?

Telmisartan+cilnidipine is not a blood thinner, and it is an anti-hypertensive medication that is used to lower blood pressure.

Can Telmisartan+cilnidipine make me dizzy?

One of the side effects of telmisartan+cilnidipine is dizziness. Patients may experience dizziness on rising up suddenly from the sitting or lying position. Patients can get up slowly from the lying position to avoid dizziness, and they can also avoid driving because it causes a lack of concentration.

Can Telmisartan+cilnidipine be used in older individuals?

Yes, this medication can be used in elderly individuals with caution. Discuss with your doctor before starting this medication in individuals above 65 years because a dose change is required.

When should you not use Telmisartan+cilnidipine?

This medication should not be used if the patients are allergic to this medication, and it is not recommended for severe liver disorders as it causes further liver damage. It should be avoided in pregnancy or if you are planning for pregnancy since it causes harmful effects on the developing baby.

Written By: Muskan Patel, M.Pharm

Reviewed By: Dr. Vishwa Patel, MBBS