DAIDZEIN,GENISTEIN,PALMITOYLETHANOLAMIDE

Background and Date of Approval

Daidzein, Genistein, and Palmitoylethanolamide belong to the therapeutic class of anti-ulcer medications.

Uses

Daidzein, Genistein, Palmitoylethanolamide is commonly used in chronic obstructive pulmonary disease (COPD), pulmonary arterial hypertension (PAH), cystic fibrosis, asthma, bronchitis, and emphysema.

How is it administered?

Daidzein, Genistein, Palmitoylethanolamide is administered orally, meaning it is taken by mouth. The capsules should be swallowed whole with water. It is important to take this medication exactly as prescribed by your doctor. Do not take more or less of it than prescribed, and do not take it more often than prescribed.

Side Effects

Possible side effects of Daidzein, Genistein, Palmitoylethanolamide are gastrointestinal, like upset stomach, diarrhea, constipation, gas, and heartburn It also leads to neurological including dizziness, drowsiness, and headache. It also causes allergic reactions, swelling, fatigue, and decreased appetite.

Warnings

Daidzein, Genistein, Palmitoylethanolamide could have serious side effects, such as a heart attack, stroke, stomach bleeding, or kidney damage. These side effects are more likely to occur in people who have a history of heart disease, high blood pressure, diabetes, asthma, or kidney disease. It can cause blood disorders, such as anemia and thrombocytopenia (low platelet count). It can weaken the immune system and increase the risk of infections.

Precautions

Take Daidzein, Genistein, Palmitoylethanolamide with food or milk to reduce stomach upset. Do not drink alcohol while taking this medication, as this can increase your risk of stomach bleeding. Avoid using it for more than ten days without talking to your doctor. If you are taking it for pain, talk to your doctor about other ways to manage it, such as physical therapy or exercise. Tell your doctor about all the medications you are taking before starting this medication. This includes prescription medications, over-the-counter medications, and herbal supplements. Tell your doctor about any medical conditions you have, including heart disease, high blood pressure, diabetes, asthma, kidney disease, and liver disease. If you experience any side effects while taking it, contact your doctor immediately.

Word of Advice

Exercise caution if you have kidney disease, liver disease, asthma, heart disease, diabetes, or are elderly before taking Daidzein, Genistein, and Palmitoylethanolamide. Avoid use during pregnancy and while breastfeeding. Use with caution if you have COPD or other respiratory conditions, as this medication may cause side effects including diarrhoea and stomach pain, which could worsen breathing difficulties. Do not drive or operate machinery while taking this medication, as it may cause drowsiness and dizziness. If you are taking this medication to prevent stomach ulcers associated with NSAID use, take it with food on a regular schedule. Seek immediate medical attention if you develop any new or unusual side effects during treatment with this medication.

References

Chaurasia et al., Therapeutic benefit of palmitoylethanolamide in the management of neuropathic pain, Romanian Neurosurgery, 2018, 4: 654 – 661, [Accessed on 05th October 2023], http://www.roneurosurgery.eu/atdoc/18ChaurasiaID_Therapeutic.pdf Frimline Pvt Ltd., [Revised on 2019] [Accessed on 05th October 2023], https://www.larenon.com/wp-content/uploads/2019/07/PALMITOLE-LBL.pdf

Frequently Asked Questions

What are the side effects of Daidzein+ Genistein + Palmitoylethanolamide?

The most common side effects of Daidzein+ Genistein + Palmitoylethanolamide are diarrhea, stomach pain, abdominal cramps, headache, nausea, vomiting, heartburn, indigestion, gas, drowsiness, dizziness, lightheadedness, weakness, and fatigue. More serious side effects can include gastrointestinal bleeding, stomach ulcers, allergic reactions, heart problems, liver problems, and kidney problems.

Who should not take Daidzein+ Genistein + Palmitoylethanolamide?

Daidzein+ Genistein + Palmitoylethanolamide should not be taken by people who are allergic to palmitoyl-L-ascorbic acid or misoprostol, women who are pregnant or breastfeeding, or people with active peptic ulcer disease or a history of gastrointestinal bleeding.

How long can I take Daidzein+ Genistein + Palmitoylethanolamide?

The length of time you can take Daidzein+ Genistein + Palmitoylethanolamide will depend on your individual condition and how well you respond to the medication. Talk to your doctor about how long you should take this medication.

What is the dosage of Daidzein+ Genistein + Palmitoylethanolamide?

The dosage of Daidzein+ Genistein + Palmitoylethanolamide will vary depending on your condition and how well you respond to the medication. Talk to your doctor about the best dosage for you.

What should I do if I miss a dose of Daidzein+ Genistein + Palmitoylethanolamide?

If you miss a dose of Daidzein+ Genistein + Palmitoylethanolamide, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for the missed dose.

What should I avoid while taking Daidzein+ Genistein + Palmitoylethanolamide?

You should avoid alcohol while taking Daidzein+ Genistein + Palmitoylethanolamide, as alcohol can increase the risk of side effects such as stomach bleeding and ulcers.

Written By: Muskan Patel, M.Pharm

Reviewed By: Dr. Vishwa Patel, MBBS