FLUTICASONE FUROATE,VILANTEROL
Background and Date of Approval
Fluticasone furoate and vilanterol is a combination medication indicated for the management of chronic obstructive pulmonary disease (COPD) and asthma. The combination comprises an inhaled corticosteroid (ICS), fluticasone furoate, and a long-acting beta-agonist (LABA), vilanterol. It functions by reducing airway inflammation and relaxing airway smooth muscle, thereby improving breathing and lung function.
Uses
Fluticasone Furoate and Vilanterol is primarily used to treat COPD and asthma. The combination works synergistically to manage symptoms such as wheezing, shortness of breath, and chronic cough. Fluticasone furoate reduces inflammation in the lungs, preventing exacerbations of asthma and COPD. Vilanterol helps relax the muscles around the airways, easing airflow and making it easier to breathe.
How is it administered?
Fluticasone Furoate and Vilanterol is administered through an inhaler device. Patients are instructed to inhale the medication once daily as directed by their healthcare provider. The inhaler should be primed before use to ensure proper delivery of the medication. Itâs important not to exceed the prescribed dosage and to follow the inhalation technique as instructed to maximise the effectiveness of the treatment.
Side Effects
Side effects are unwanted symptoms caused by medicines. Although all drugs can cause side effects, not everyone experiences them. Common side effects of Fluticasone furoate and Vilanterol: Throat irritation or dryness Coughing or hoarseness Headache Upper respiratory tract infections Serious side effects of Fluticasone furoate and Vilanterol: Paradoxical bronchospasm (worsening shortness of breath or wheezing) Tachycardia (rapid heart rate) Chest pain or palpitations Oral thrush (fungal infection in the mouth) Corticosteroid-related effects (e.g., weakened immune system, osteoporosis, adrenal suppression)
Warnings
Pregnancy and breast-feeding: Consult your healthcare provider before use if you are pregnant or breastfeeding. The safety of this combination during pregnancy and breastfeeding has not been fully established. Asthma-related risk: LABAs like vilanterol can increase the risk of severe asthma exacerbations. Always use the medication as prescribed, and do not use it for acute attacks. Heart conditions: Fluticasone Furoate and Vilanterol may cause an increased heart rate. Patients with heart problems such as arrhythmias or hypertension should use this medication with caution and under medical supervision. Infections: Fluticasone Furoate can weaken the immune system, increasing the risk of infections, particularly fungal or viral infections in the mouth and throat. Liver or kidney issues: If you have liver or kidney disease, consult your healthcare provider before starting this medication, as adjustments to the dosage may be necessary.
Precautions
Take precautions when using Fluticasone Furoate and Vilanterol to ensure safe and effective use. First, learn and practice the proper inhalation technique to ensure the medication reaches your lungs. Schedule regular medical check-ups to monitor your lung function and detect potential side effects early. Always follow the prescribed dosage and avoid exceeding it, as this may increase the risk of side effects. Never stop using the medication suddenly without consulting your healthcare provider, as this could worsen your asthma or COPD symptoms.
Word of Advice
Fluticasone furoate and vilanterol should be used strictly as prescribed by your doctor. Follow the dosage instructions provided and remain alert to potential side effects. Should your symptoms worsen or any adverse reactions occur, inform your doctor without delay. Attend all scheduled follow-up appointments and monitor your condition regularly. This combination is not intended for acute asthma attacks; ensure you have a separate rescue inhaler available for emergency use. Supporting your respiratory health through a balanced diet and regular exercise complements medical treatment.
References
1. Albertson TE, Richards JR, Zeki AA. The combination of fluticasone furoate and vilanterol trifenatate in the management of asthma: clinical trial evidence and experience. https://pmc.ncbi.nlm.nih.gov/articles/PMC5933662/ 2. Prabhudesai P, Singh BP, Agrawal G, Singh AK, Jadhav AY, Patil SR, Bhagat S, Patil S, Barkate H. Fluticasone Furoate/Vilanterol Use Trends and Characteristics in Patients With Obstructive Airway Disease: A Real-World Study of 10,374 Patients From India. https://pmc.ncbi.nlm.nih.gov/articles/PMC10008380/ 3. Janson C. Treatment with inhaled corticosteroids in chronic obstructive pulmonary disease. https://pmc.ncbi.nlm.nih.gov/articles/PMC7212119/
Frequently Asked Questions
What is fluticasone furoate and vilanterol used for?
Fluticasone furoate and vilanterol are used to treat chronic obstructive pulmonary disease (COPD) and asthma. They help reduce inflammation and relax the airways, improving breathing and reducing symptoms such as wheezing and shortness of breath.
What does fluticasone furoate and vilanterol do to the lungs?
Fluticasone furoate and vilanterol work together to improve lung function. Fluticasone furoate reduces inflammation in the airways, helping prevent flare-ups. Vilanterol relaxes the muscles around the airways, making it easier to breathe and improving airflow. Together, they help manage symptoms of asthma and COPD.
What is the best time to take fluticasone furoate and vilanterol?
The best time to take fluticasone furoate and vilanterol is once daily, at the same time each day, to help maintain consistent levels of the medication in your system. It is generally recommended to take it in the evening, but follow your healthcare provider's advice for your specific needs.
Is fluticasone furoate and vilanterol safe to use daily?
Yes, fluticasone furoate and vilanterol are safe to use daily when taken as prescribed. The medication is designed for long-term, once-daily use to manage asthma and COPD. However, always follow your healthcare providerâs instructions and attend regular check-ups to monitor your condition.
What are the side effects of fluticasone furoate and vilanterol for the heart?
Fluticasone furoate and vilanterol can cause an increased heart rate (tachycardia) and palpitations in some patients. In rare cases, it may also trigger irregular heart rhythms or chest pain. People with existing heart conditions should use this medication with caution and under medical supervision.
Is fluticasone furoate and vilanterol a strong steroid?
Fluticasone furoate is a corticosteroid, but it is not considered a "strong" steroid. It effectively reduces inflammation in the airways with a lower risk of systemic side effects compared to stronger steroids. It works locally in the lungs to manage conditions like asthma and COPD without significant impact on the rest of the body.