IRON(III)ISOMALTOSIDE
Background and Date of Approval
Iron (III) Isomaltoside received U.S. FDA approval on 16 January 2020 for neurological disorders. The medication is classified as an anti-anemic medicine.
Uses
Iron (III) Isomaltoside is used as an iron replacement medicine to treat iron deficiency anemia in adults who are intolerant to oral iron or have not responded well to oral iron preparations. Additionally, this medication treats this condition in individuals with chronic kidney disease who are on dialysis and cannot take oral iron supplementation.
How is it administered?
Iron (III) Isomaltoside will be administered to you by a healthcare professional in a hospital setting. It is usually administered in a vein (intravenous) or into the dialyzer. Your doctor will decide the dose, route of administration, and frequency based on your disease condition and other factors.
Side Effects
The most common side effects of Iron (III) Isomaltoside are rash and nausea. Serious side effects while taking Iron (III) Isomaltoside are severe allergic reactions (rash, itching, dizziness, low blood pressure, breathing problems), and iron overload.
Warnings
Iron (III) Isomaltoside should not be consumed if you are allergic to Iron (III) Isomaltoside or any of its ingredients in the medication. Do not take this medicine if the anemia was not caused by iron deficiency (such as "hemolytic" anemia), or if you have iron overload or impaired iron utilization in the body if you have a history of severe allergic reactions to other injectable iron preparations and active liver disease. Due to limited data on safety and efficacy, Iron (III) Isomaltoside is not recommended for use in individuals under the age of 18, including children and adolescents.
Precautions
Notify your doctor if you are pregnant, planning to get pregnant, or think you may be pregnant or breastfeeding. Before receiving Iron (III) Isomaltoside, it is important to inform your doctor if you have a history of medicine allergy, systemic lupus erythematosus, rheumatoid arthritis, or severe asthma. Notify your doctor if you have eczema, or other allergies, an ongoing bacterial infection in your blood, or reduced liver function.
Word of Advice
Patients with liver disease should use Iron (III) Isomaltoside with caution and inform their doctor of all underlying medical conditions. Do not discontinue the medicine until advised by your doctor. Do not take a double dose to compensate for a missed dose. Do not breastfeed while taking Iron (III) Isomaltoside unless your doctor advises otherwise. Notify your doctor if you experience any serious adverse effects. Contact your doctor for additional information. Store out of reach of children and pets. Do not freeze the medicine. Do not store above 30°C. Always check the expiry date before use.
References
Pharmacosmos A/S, Electronic Medicines Compendium (EMC), [Revised on January 2023] [Accessed on 21st June 2023], *pil.13404.pdf (medicines.org.uk) Pharmacosmos A/S, US Food, and Drug Administration, [ Revised on Jan 2020] [ Accessed on 21st June 2023], https://www.accessdata.fda.gov/drugsatfda_docs/label/2020/208171s000lbl.pdf Thomas AR Mace, Ahsan Syed, Sunil Bhandari; Iron (III) isomaltoside 1000; Expert Review of Hematology; Published on June 2013; 21st June 2023; https://pubmed.ncbi.nlm.nih.gov/23782077/
Frequently Asked Questions
How to manage the side effects of Iron (III) Isomaltoside?
To manage the side effects of Iron (III) Isomaltoside, follow the prescribed dosage, and report side effects promptly. Stay hydrated, and this medicine can cause constipation in some individuals. To manage this, ensure you consume a fiber-rich diet, and stay physically active. Maintain a healthy lifestyle, and attend follow-up appointments.
Can you take Iron (III) Isomaltoside when pregnant?
Limited information is available on the use of Furosemide during pregnancy. Notify your healthcare professional if you are pregnant or planning to have a baby think you may be pregnant. Additionally, consult your medical professional regarding the use of Iron (III) Isomaltoside during breastfeeding. The potential benefits and risks should be carefully assessed. Your doctor will suggest taking this medicine only if it's necessary.
What are the side effects of Iron (III) Isomaltoside?
Common side effects of Iron (III) Isomaltoside include rash and nausea . It is crucial to consult your doctor for any concerns or persistent side effects.
Can Iron (III) Isomaltoside interact with other medications?
Yes, Iron (III) Isomaltoside can interact with other medications and can cause undesirable side effects. Inform your doctor about any prescribed medications, over-the-counter medicines, nutritional or vitamin supplements, and herbal products you take or have taken before the treatment.
How is Iron (III) Isomaltoside administered?
Iron (III) Isomaltoside is typically administered intravenously (IV) or into the dialyzer as a solution for injection. The dosage and administration schedule will be determined by your doctor based on your specific condition and needs.