LACTULOSE
Background and Date of Approval
Lactulose received U.S. FDA approval in June 1977 for the treatment of constipation and hepatic encephalopathy.
Uses
Lactulose is used to treat constipation and hepatic encephalopathy
How is it administered?
The recommended dose of Lactulose is 2 to 3 tabelspoons or 15 ml. Shake the bottle well and take the prescribed dose or quantity by mouth using the measuring cup or spoon provided by the pack. You can also mix it with water or fruit juice. Dissolve the contents in water and consume it.
Side Effects
The common side effects that are likely to occur while you are on the treatment with Lactulose are abdominal pain, diarrhea, nausea, vomiting, flatulence (wind), and electrolyte imbalance. Inform your healthcare professional if any of these side effects disturb you or persist. Report to your doctor immediately if you have diarrhea.
Warnings
Contact your physician immediately if you experience allergies to Lactulose and its ingredients. Inform your physician if you have galactosemia (galactose indigestion disorder) and have a blockage caused by normal constipation or digestive perforation. Tell your physician if you have diabetes or lactose intolerance (unable to digest milk sugar). When you have diabetes, your dose of this medication will be increased because it contains high sugar content, and you will need to adjust it. Chronic usage of incorrect dosages or misuse might result in diarrhea and electrolyte imbalance, so take it only as directed by your doctor.
Precautions
Lactulose solution is safe to use during pregnancy as this medicine does not cause any harmful effects on an unborn baby. Avoid breastfeeding your baby while on the medicine as it is unknown if Lactulose passes into the breastmilk.
Word of Advice
Inform your doctor before starting treatment if you have planned surgery or investigations of the rectum or colon. Lactulose solution should not be given to children under 14 years of age without prior medical consultation. Adequate fluid intake, particularly water, is important to maintain hydration. Increased dietary fibre and regular physical activity may help soften stools and facilitate bowel movement. Avoid retaining stools, as this can aggravate bowel dysfunction.
References
KD Tripathi, Essentials of Medical Pharmacology, Osmotic purgatives, 7th Edition, 2013, 677-679. Intrapharm Laboratories Limited., Electronic Medicines Compendium (EMC), [Revised on May 2015] [Accessed on 28th September 2022] https://www.medicines.org.uk/emc/files/pil.2796.pdf Cresent pharma limited., Accessed on 28th September 2022, https://mhraproductsprod.blob.core.windows.net/docs/25c876b655ff167e28fd9a2d39114d48b4dbf1b7
Frequently Asked Questions
Is Lactulose solution a laxative?
Yes, Lactulose solution is a laxative that draws water into the bowel, softening and making the feces easier to pass, thereby relieving constipation. It is also used to decrease the ammonia level in the blood of patients with liver disease.
When should I not take Lactulose?
Lactulose should not be taken if you are allergic to Lactulose and its ingredients. If you have diabetics, galactosemia (galactose indigestion disorder), or lactose intolerance, avoid taking Lactulose.
What are lactulose side effects?
Abdominal pain, diarrhea, nausea, vomiting, flatulence (wind), and electrolyte imbalance due to diarrhea are the common side effects of Lactulose.
I am pregnant. Can I take Lactulose while pregnant?
Yes. Lactulose Solution is completely safe to be administered while pregnancy as it does not have any harmful effects on the developing baby.
Can I take Lactulose after eating?
Yes, Lactulose can be taken with or without food. You can take this medication to be mixed with water, fruit juice, or meals.
What happens if I have too much Lactulose?
Diarrhea and stomach pain can occur if you take too much Lactulose.