LAMIVUDINE,TENOFOVIR DISOPROXIL FUMARATE
Background and Date of Approval
Lamivudine and Tenofovir Disoproxil Fumarate are antiretroviral medicines used in the treatment of HIV (human immunodeficiency virus) infection.
Uses
Lamivudine, Tenofovir Disoproxil Fumarate has been developed to treat Human Immunodeficiency Virus (HIV-1). It is a nucleotide reverse transcriptase inhibitor (NRTI) and works by inhibiting the enzymes (HIV reverse transcriptase) important for virus replication. This tablet is not studied in patients over 65 years of age.
How is it administered?
Lamivudine, Tenofovir Disoproxil Fumarate tablet are always taken at the dose recommended by your doctor or health care provider. Your physician will choose the dosage and administration frequency based on the medical condition because it differs for each person. Do not crush, chew or break the tablet.
Side Effects
The common side effects that are likely to occur while you are on the treatment with Lamivudine, Tenofovir Disoproxil Fumarate tablet are headach, stomach pain, tiredness, bloating, flatulence, low phosphate levels in the blood, diarrhea, dizziness, joint pain, sickness, rash, weakness. Some serious adverse reactions include kidney damage, deep, rapid breathing, drowsiness, nausea, vomiting, lactic acidosis (excess lactic acid), infection, increased liver enzymesIf you experience any allergic reactions after taking this tablet, report to your doctor immediately.
Warnings
Do not consume Lamivudine, Tenofovir Disoproxil Fumarate tablet if you have experienced allergic reactions to Lamivudine, Tenofovir Disoproxil Fumarate, peanuts, or soya, (as this medicine contains lecithin) or any of its other medical ingredients. During the Lamivudine, Tenofovir Disoproxil Fumarate treatment, your doctor may periodically monitor your blood counts, bone mineral density, a history of the liver (chronic hepatitis B or C), and kidney parameters to prevent serious complications. Report to your doctor if you have had a history of heart failure, bone disease, fractures, liver or kidney problems.
Precautions
Adults of childbearing potential should consider using an effective contraceptive to prevent unwanted pregnancy. If you are pregnant or think you might be pregnant, your physician might suggest an alternative treatment, as this medication is not recommended during early pregnancy. Breastfeeding is not recommended due to the potential transmission of HIV from the mother to the baby. Inform your doctor about your underlying infections. If you have advanced HIV (AIDS), you may develop signs of infection and inflammation or worsen the signs of an existing infection once treatment is started. Report your doctor for side effects.
Word of Advice
Lamivudine and Tenofovir Disoproxil Fumarate may cause dizziness and fatigue. Avoid driving or operating machinery during treatment. Consult your healthcare provider before starting this medication. This medicine does not reduce the risk of transmitting HIV to others through sexual contact or blood exposure. Continued use of the medication is necessary to prevent this complication.
References
Goodman & Gilmanâs, The Pharmacological Basics of Therapeutics, Antiretroviral agents and treatment of HIV infection, 12th edition, 2011, 1632-1634. KD Tripathi, Essentials of Medical Pharmacology, Antiviral drugs, 7th edition, 2013, 809-810. Cipla (EU) Limited, Electronic Medicines Compendium (emc), [ Revised on October 2017] [ Accessed on Accessed on 20th May 2023], https://www.medicines.org.uk/emc/files/pil.10500.pdf
Frequently Asked Questions
How will I receive the Lamivudine, Tenofovir Disoproxil Fumarate tablet?
Always take the Lamivudine, Tenofovir Disoproxil Fumarate tablet as prescribed by your doctor. Take the tablet with or without food. Do not break, chew, crush, or break the tablet. Swallow the whole tablet with water.
How can I manage side effects while taking Lamivudine, Tenofovir Disoproxil Fumarate tablet?
Contact your physician immediately if you experience any side effects while taking Lamivudine, Tenofovir Disoproxil Fumarate tablet. Your physician may also recommend over-the-counter or prescription medications to help manage your side effects.
How do you know if you are hypersensitive to Lamivudine, Tenofovir Disoproxil Fumarate tablet?
Watch out for symptoms like severe rash, rash accompanied by fever, muscle pain, extreme tiredness, facial edema, breathing difficulty, blisters, and peeling of the skin, and reach out to your healthcare provider instantly if you notice any of these symptoms.
What is the combination of Lamivudine, and Tenofovir Disoproxil Fumarate?
Lamivudine, Tenofovir Disoproxil Fumarate tablet is a combination of Lamivudine, Tenofovir Disoproxil Fumarate.
Can I pass the HIV injection even after consuming Lamivudine, Tenofovir Disoproxil Fumarate tablet?
Yes, Lamivudine, Tenofovir Disoproxil Fumarate tablet is not a cure for HIV. Make sure you dont pass the infection. Always use effective contraception during sexual activities. Do not share personal items like razors, brushes, towels, etc.