LATANOPROST

The U.S. FDA approved latanoprost for ocular use in 1996. Latanoprost is a prostaglandin analog that works by mimicking the action of prostaglandin, a naturally occurring substance in the body.

Latanoprost treats open-angle glaucoma and ocular hypertension in adults. They work by reducing the pressure in the eye, achieved by enhancing the natural drainage of fluid from the eye into the bloodstream. Also, it is used to treat increased eye pressure and glaucoma in children and babies of all ages.

Use the Latanoprost as your physician advises. Do not take more or less of the eye drops than your doctor has instructed. Your physician will decide the correct dosage and duration based on age, body weight, and disease condition.

The most common side effects of Latanoprost are gradual change in eye color (increasing brown pigment), redness of the eye, eye irritation (burning, itching, stinging), changes to eyelashes and fine hairs around the treated eye (mainly in people of Japanese origin), irritation or disruption to the eye surface, eyelid inflammation (blepharitis), eye pain, and light sensitivity (photophobia).

Do not use Latanoprost if you are allergic to Latanoprost, benzalkonium chloride, or any of its ingredients. Do not use this eyedrop if you are pregnant, or think you may be pregnant, or planning to get pregnant, or if you are breastfeeding. Before using this eye drop for yourself or your child, it's crucial to consult your doctor if you or your child are planning to have or have had eye surgery, have any eye problems like pain, irritation, or blurred vision, or experience dry eyes. These eye drops have not been studied in infants born prematurely (less than 36 weeks gestation).

Notify your doctor if you have severe or poorly controlled asthma, wearing contact lenses, or have had a viral eye infection caused by the herpes simplex virus (HSV). When using Latanoprost, there is a possibility of pigmentation changes in your iris, periorbital tissue (eyelid), and eyelashes. This pigmentation in the iris is likely to be permanent, while changes to eyelashes, such as increased length, thickness, and number, are usually reversible. It's essential to stay informed about these effects and discuss any concerns with your healthcare provider. Store the unopened bottle in a refrigerator (2°C - 8°C). After opening, store it below 25°C and use within 4 weeks.

Remove your contact lenses before applying Latanoprost eye drops. After instilling the drops, wait at least 15 minutes before reinserting your contact lenses to reduce the risk of interaction. If you use other eye drops, leave an interval of at least five minutes between Latanoprost and the other eye medication to allow proper absorption and effectiveness.

Use only the prescribed number of drops, as applying too much may cause mild eye irritation, watering, or redness. Follow these instructions carefully to ensure safe and effective treatment, and contact your doctor if you have any concerns or experience persistent discomfort.

Tubilux pharma S.p.A; Electronic medicines compendium (emc); [Revised on March 2022] [ Accessed on 26th July 2023] *pil.6945.pdf (medicines.org.uk) Pfizer; [Accessed on 26th July 2023], http://labeling.pfizer.com/ShowLabeling.aspx?id=613 Pfizer; U.S Food & Drug Administration FDA; [Revised on June 2014] [ Accessed on 26th July 2023.] https://www.accessdata.fda.gov/drugsatfda_docs/label/2014/020597s045s048lbl.pdf Jeffrey D. Henderer and Christopher J. Rapuano, Ocular Pharmacology, Goodman & Gilman's Pharmacological Basis of Therapeutics, 2011, Page 1773-1801.