LATANOPROST,TIMOLOL

The U.S. FDA approved the combination of Latanoprost and Timolol for ophthalmic use in 1996. Latanoprost is a prostaglandin analog that helps increase the natural drainage of fluid from the eye into the bloodstream. Timolol is a beta-blocker that works by reducing the production of fluid inside the eye. Together, these medicines help regulate eye pressure.

Latanoprost + Timolol treats open-angle glaucoma and ocular hypertension in adults. They work by reducing the pressure in the eye and enhancing the natural drainage of fluid from the eye into the bloodstream.

Use the Latanoprost + Timolol as your physician advises. Do not take more or less of the eye drops than your doctor has instructed. Your physician will decide the correct dosage and duration based on age, body weight, and disease condition.

The most common side effects of Latanoprost + Timolol are gradual change in eye color (increasing brown pigment), redness of the eye, eye irritation (burning, itching, stinging), changes to eyelashes and fine hairs around the treated eye (mainly in people of Japanese origin), irritation or disruption to the eye surface, eyelid inflammation (blepharitis), eye pain, and light sensitivity (photophobia).

Do not use Latanoprost + Timolol if you are allergic to Latanoprost, Timolol, beta-blockers, or any other ingredients. Avoid using them if you have or had respiratory issues like asthma or severe chronic obstructive bronchitis. These drops are not suitable if you have significant heart problems or heart rhythm disorders. Latanoprost + Timolol should be used cautiously in lung patients. Before starting the treatment, inform your physician about pre-existing lung conditions. Do not use this eyedrop if you are pregnant, think you may be pregnant, plan to get pregnant, or are breastfeeding. Before using this eye drop, consult your doctor if you or your child have or have had conditions such as coronary heart disease, heart failure, low blood pressure, or slow heartbeat. These eye drops are suitable for adult men and women, including the elderly, but should not be used by individuals under the age of 18.

Notify your doctor if you have breathing problems like asthma or chronic obstructive pulmonary disease, poor blood circulation diseases like Raynaud's disease, diabetes, overactivity of the thyroid gland, or are about to undergo eye surgery. Report to your doctor if you have experienced eye problems like pain, irritation, inflammation, or blurred vision or if you know you have dry eyes, wear contact lenses, suffer from angina, severe allergic reactions, or have had a viral eye infection caused by the herpes simplex virus. Let your doctor know before any surgery, as these eye drops might interact with anesthesia medications.

Remove your contact lenses before applying Latanoprost + Timolol eye drops. After using the drops, wait at least 15 minutes before putting your contact lenses back in to help prevent potential interactions. If you need to use other eye drops, maintain an interval of at least five minutes between applications to support proper absorption and effectiveness.

Use only the recommended number of drops, as applying more than prescribed may cause mild irritation, excessive watering, or redness. Following these instructions can help ensure safe and effective use of the eye drops. Contact your doctor if you have any concerns or experience persistent eye discomfort.

Tubilux pharma S.p.A; Electronic medicines compendium (emc); [Revised on March 2022] [ Accessed on 26th July 2023] *pil.6945.pdf (medicines.org.uk) Pfizer; [Accessed on 26th July 2023], http://labeling.pfizer.com/ShowLabeling.aspx?id=613 Pfizer; U.S Food & Drug Administration FDA; [Revised on June 2014] [ Accessed on 26th July 2023.] https://www.accessdata.fda.gov/drugsatfda_docs/label/2014/020597s045s048lbl.pdf Jeffrey D. Henderer and Christopher J. Rapuano, Ocular Pharmacology, Goodman & Gilman's Pharmacological Basis of Therapeutics, 2011, Page 1773-1801.