LEVODOPA,BENSERAZIDE HYDROCHLORIDE

Background and Date of Approval

Levodopa with benserazide hydrochloride is approved for the treatment of Parkinson's disease.

Uses

Levodopa + benserazide hydrochloride treats bacterial infections (respiratory tract, urinary tract, nervous system, digestive system, and blood poisoning. It is effective only against bacterial infection and not against viral or fungal infection.

How is it administered?

Levodopa + benserazide hydrochloride is available as tablet form, which can be consumed orally. Your physician will decide the correct dosage and duration based on age, body weight, and disease condition. Only stop taking the tablet if your doctor advises you to stop.

Side Effects

The common side effects that are experienced while you are on the treatment with Levodopa + benserazide hydrochloride are nausea, vomiting, headache, dizziness, dryness in the mouth, anxiety, constipation, abnormal dreams, feeling sleepy. Inform your doctor immediately if you have allergic reactions (itching, rash), uneven heartbeat, bleeding in the stomach or intestines (black and tarry stools), low blood cell counts.

Warnings

Consult your doctor if you are planning to get pregnant or think you may be pregnant while breastfeeding. Make sure you inform the physician of all the medications, including herbal medications and supplements, you are taking before you start treatment with tablets. Use effective birth control during the treatment while taking the medicine.

Precautions

Before taking the Levodopa + benserazide hydrochloride you need to inform your physician if you have eye diseases, heart problems, kidney diseases, liver diseases, mental health problems, ulcers, diabetes, or have ever had skin cancer. If you are going to have an operation, inform your doctor that you are taking this medication.

Word of Advice

Attend all recommended blood or urine tests to help your doctor monitor how Levodopa + Benserazide hydrochloride is affecting your body. Inform your healthcare provider promptly if you experience any side effects or have concerns during treatment.

Use caution when driving or operating machinery, especially if the medicine causes drowsiness or sudden sleepiness. Adjust your activities accordingly and seek medical advice when needed. If you experience digestive problems such as nausea or loss of appetite, discuss possible adjustments to the timing of your medication with your doctor.

Stay in regular communication with your healthcare team and report any changes in your health without delay. Follow the prescribed dosage and instructions carefully, and consult your healthcare provider for individualized advice, particularly regarding other medicines you may be taking and potential drug interactions.

References

Roche Products Limited, Electronic medicines compendium (EMC), [ Revised on May 2019] [ Accessed on 12th Jan 2022], https://www.medicines.org.uk/emc/files/pil.6926.pdf Goodman & Gilman's, The Pharmacological Basis of Therapeutics, Treatment of central nervous system degenerative disorders, and cytokines, 12th edition, 2011, 614-619. KD Tripathi, Essentials of Medical Pharmacology, Antiparkinsonian drugs, 7th edition, 2013, 425-435.

Frequently Asked Questions

Can Levodopa + benserazide hydrochloride cause changes in taste?

Yes, some individuals may experience changes in how things taste or a loss of taste. This is generally temporary.

How quickly can Levodopa + benserazide hydrochloride induce sleepiness?

Levodopa, one of the components of the Levodopa + benserazide hydrochloride, can lead to sudden sleepiness, even during the day. Exercise caution and refrain from driving or using machinery if affected.

What's the significance of red urine?

Red urine is a normal, non-concerning effect. It results from the body eliminating the medicine and is not a cause for worry.

Can Levodopa + benserazide hydrochloride be taken with antacids or other digestive medications?

Consult your doctor before combining Levodopa + benserazide hydrochloride with antacids, or other medications affecting digestion to prevent potential interactions.

Can Levodopa + benserazide hydrochloride cause unusual urges or behaviors?

Yes, it may lead to impulse control disorders. If you notice unusual behaviors like excessive gambling, altered sexual interest, or compulsive actions, inform your doctor promptly.

Written By: Muskan Patel, M.Pharm

Reviewed By: Dr. Vishwa Patel, MBBS