PILORI

Background and Date of Approval

Pilori is classified as an anti-ulcer agent.

Uses

Pilori is a prescription medication for peptic ulcers caused by Helicobacter pylori (H. pylori). It can improve the symptoms of gastroesophageal reflux disease (GERD).

How is it administered?

Pilori is administered orally, meaning that it is taken by mouth. It is important to take the medicine as prescribed by your doctor. Your healthcare provider will provide the exact dosing instructions, so it is crucial to follow their recommendations carefully.

Side Effects

The most common side effects of Pilori are mild and go away on their own. These side effects may include nausea, vomiting, diarrhea, abdominal pain, headache, dizziness, and fatigue. Less common side effects of this medication are more serious and require medical attention. These side effects include allergic reactions, liver damage, and kidney damage.

Warnings

Pilori can cause allergic reactions, including hives, swelling of the face, lips, tongue, or throat, difficulty breathing, and dizziness. It can cause liver damage, especially in people with pre-existing liver disease. It can cause kidney damage, especially in people with pre-existing kidney disease.

Precautions

If you experience these symptoms, stop taking Pilori immediately and contact your doctor. If you experience any signs of liver damage, such as jaundice (yellowing of the skin and eyes), dark urine, or pale stools, stop taking it immediately and contact your doctor. If you experience any signs of kidney damage, such as decreased urination, swelling of the hands, feet, or face, or blood in the urine, stop taking it immediately and contact your doctor.

Word of Advice

Inform your doctor about your medical conditions and all medications you are currently taking before beginning Pilori. Use with caution if you have moderate to severe kidney disease, a history of allergic reactions to antibiotics or other medications, electrolyte imbalances, or if you are taking certain medications concurrently, such as warfarin, methotrexate, or digoxin. Be alert to the signs and symptoms of allergic reactions. Should you experience any of the following symptoms after taking this medication, discontinue it immediately and contact your doctor. Take only the dose prescribed. Do not extend the duration of treatment beyond what has been prescribed. Pilori should be taken only under medical supervision. Do not self-medicate.

References

I.D. Penman, C.W. Lees, Alimentary tract and pancreatic disease, Davidson’s Principles & Practice of Medicine, 22nd Edition, 2014, 837-920. Keith A. Sharkey, Wallace K. MacNaughton, Pharmacotherapy for Gastric Acidity, Peptic Ulcers, and Gastroesophageal Reflux Disease, Goodman & Gilman’s Pharmacological Basis of Therapeutics, 13th Edition, 2018, 909-919. MISSION PHARMACAL COMPANY, US Food & Drug Administration, [Revised on Jun 2019] [Accessed on 10th Oct 2023], https://www.accessdata.fda.gov/drugsatfda_docs/label/2019/021618s006lbl.pdf BROWN & BURK UK LIMITED, Electronic Medicines Compendium (EMC), [Revised on Jan 2020] [Accessed on 10th Oct 2023], https://www.medicines.org.uk/emc/files/pil.10637.pdf

Frequently Asked Questions

What are the side effects of Pilori?

The most common side effects of Pilori are nausea, vomiting, diarrhea, and abdominal pain. Other side effects may include headache, dizziness, fatigue, and a metallic taste in the mouth. Serious side effects, including allergic reactions, liver damage, and kidney damage, are rare.

How do I take Pilori?

Pilori is usually taken twice a day for seven days. It is important to take the medication as your doctor prescribes, even if you start feeling better sooner. Not finishing the full course of antibiotics can lead to the infection returning.

What should I do if I miss a dose of Pilori?

If you miss a dose of Pilori, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for the missed dose.

What should I do if I overdose on Pilori?

If you overdose on Pilori, immediately contact your doctor or poison control center. Symptoms of an overdose on this medication may include nausea, vomiting, diarrhea, abdominal pain, headache, dizziness, and fatigue. In serious cases, an overdose of this medication can lead to allergic reactions, liver damage, and kidney damage.

How long does it take to see results after taking Pilori?

Most people start to feel better within a few days of starting Pilori. However, it is important to finish the full course of antibiotics, even if you start to feel better sooner. Not finishing the full course of antibiotics can lead to the infection returning.

Can I buy Pilori over the counter?

Pilori is a prescription medication that can only be obtained from a doctor or pharmacy.

Written By: Muskan Patel, M.Pharm

Reviewed By: Dr. Vishwa Patel, MBBS