RECOMBINANT HUMAN EPIDERMAL GROWTH FACTOR GEL
Background and Date of Approval
Recombinant human epidermal growth factor has been approved for medical use to enhance wound healing in burns and diabetic foot ulcers.
Uses
Recombinant human epidermal growth factor is used for the faster healing of diabetic foot ulcers in patients with diabetes and helps to prevent the amputation (a process of surgical removal of all or part of body extremity) in such patients. The lower strength of this medicine is used for first and second-degree burns, skin grafts and also in the management of bedsores.
How is it administered?
Recombinant human epidermal growth factor is available as a gel with three different strengths: 7.5g, 15g, and 30g for topical use. To be used only when directed by a physician.
Side Effects
Side effects are undesirable symptoms that can result from medication use, although not everyone may experience them. Common side effects associated with using this gel include redness of the skin, skin rash, skin discoloration, skin irritation, a burning sensation on the skin, and dry skin. It's essential to be aware of these potential effects and consult with your healthcare provider if you encounter any persistent or bothersome symptoms during the course of using the gel.
Warnings
Before using recombinant human epidermal growth factor (rhEGF) gel, it is crucial to inform your physician if you are pregnant, breastfeeding, have lung or liver conditions, or are uncertain about potential interactions with alcohol. Exercise caution and seek medical advice to ensure the gel's safety in these situations.
Precautions
To ensure the safe application of recombinant human epidermal growth factor gel, keep it out of reach of children, and perform a patch test before widespread use. Apply the gel topically using a sterile cotton swab as directed by the physician, avoiding direct contact with the wound. Clean the wound area before each application, use a single tube per patient, and adhere to the specified instructions. Consult your healthcare provider for personalized guidance based on your medical history.
Word of Advice
For the best possible results when using recombinant human epidermal growth factor gel, follow the recommended application instructions carefully. Use only one tube as directed, and do not use the product without guidance from a healthcare professional. Check the expiry date and ensure the gel is still within its recommended shelf life.
Apply the gel only to the external affected area and avoid contact with the eyes. Clean the affected area before application as instructed. It is also important to keep your healthcare provider informed about your medical history and any medications you are taking. Following these precautions and maintaining open communication with your healthcare team can help support effective treatment and healing.
References
Bharath Biotech International, Manufacturer, [Accessed on Nov 2023] https://www.bharatbiotech.com/images/regend150/REGEN-D150_ppi.pdf Hong JP, et al., Recombinant human epidermal growth factor (EGF) to enhance healing for diabetic foot ulcers. Ann Plast Surg [Published in Apr 2006] [Accessed in Nov 2023] https://pubmed.ncbi.nlm.nih.gov/16557070/
Frequently Asked Questions
Can I use the recombinant human epidermal growth factor gel without a prescription?
No, this gel is specifically designed for prescribed use. Always follow your healthcare provider's instructions for optimal results and safety.
Is it safe to apply the gel on burns of any degree?
The gel is generally suitable for first and second-degree burns. However, it's crucial to consult your physician for personalized guidance based on the specific nature of your burn.
How long should I continue using the gel for diabetic foot ulcers?
Follow your doctor's recommendation, usually around 2 to 3 weeks. However, the duration may vary based on the severity of the condition and your individual response to the treatment.
Can I share the gel with someone else who has a similar condition?
It is strongly advised against sharing the gel. For hygiene and safety reasons, each individual should use a separate tube to prevent the risk of contamination.