RISPERIDONE
Background and Date of Approval
Risperidone received approval from the U.S. Food and Drug Administration (FDA) in 1993. It is prescribed to manage symptoms of schizophrenia, bipolar disorder, and irritability associated with autism. As an atypical antipsychotic, it functions by balancing neurotransmitters in the brain, particularly dopamine and serotonin, to improve mood, thinking, and behaviour. In India, Risperidone has been available since the late 1990s and forms part of standard treatment options in psychiatric care.
Uses
Risperidone is prescribed to treat: Schizophrenia in adults and adolescents Bipolar disorder for managing manic or mixed episodes Irritability associated with autism in children and adolescents
Side Effects
Common side effects may include: Drowsiness or sleepiness Increased appetite and weight gain Dizziness or lightheadedness Dry mouth Fatigue Serious side effects (seek medical help immediately): Difficulty breathing Irregular heartbeat Muscle stiffness or uncontrollable movements Severe allergic reactions like rash, swelling, or itching
Warnings
Increased risk of mortality in elderly patients with dementia-related psychosis. May cause serious movement disorders such as tardive dyskinesia. Risk of neuroleptic malignant syndrome (NMS), a potentially life-threatening condition. May increase blood sugar and cholesterol levels. Not recommended for use in patients with known hypersensitivity to Risperidone or any of its components.
Precautions
Regular monitoring of blood glucose and lipid profile is advised, especially in diabetic patients. Caution is advised in patients with a history of seizures, heart disease, or low white blood cell count. Avoid alcohol while taking Risperidone, as it can enhance side effects such as drowsiness or dizziness. Pregnancy and Breastfeeding: Consult your doctor before use; may not be safe. Driving and Operating Machinery: May cause drowsiness or impair judgment.
References
https://www.ncbi.nlm.nih.gov/books/NBK459313/ https://pmc.ncbi.nlm.nih.gov/articles/PMC8386072/ https://www.sciencedirect.com/science/article/pii/S0920996421004515
Frequently Asked Questions
Can Risperidone be used for depression?
Risperidone is not typically prescribed for depression alone. However, it may be used as an add-on treatment for certain mood disorders under medical supervision.
Is Risperidone addictive?
Risperidone is not addictive, but it should only be used under a doctor’s guidance. Stopping the medicine suddenly may cause withdrawal symptoms.
Can children take Risperidone?
Yes, Risperidone is approved for use in children above 5 years for irritability related to autism or schizophrenia, under strict medical supervision.
What is the time taken for Risperidone to work?
It may take 1 to 2 weeks to notice improvement in symptoms, while full effects may take several weeks.
How much is Risperdal consta injection cost?Â
Risperdal Consta injection costs approximately â¹9000 per pack (50 mg strength) in India, and you can get low pricing on platforms like MrMed for potential savings on this antipsychotic injection.