ROSUVASTATIN,FENOFIBRATE
Background and Date of Approval
Rosuvastatin and fenofibrate is an antihyperlipidaemic drug belonging to the category of medicines known as statins and fibric acid derivatives. It was approved in 2003 to treat hyperlipidaemia.
Uses
Rosuvastatin, Fenofibrate has been developed to treat hyperlipidaemia.
How is it administered?
It is an orally available prescription drug. Your doctor will decide the dose and duration of this tablet based on the disease condition and other factors. Always take this medicine as prescribed by your doctor. Do not chew, crush, or break the tablet. Swallow the whole tablet with water.
Side Effects
The common side effects that are likely to occur while you are on the treatment with Rosuvastatin, Fenofibrate are headache, muscle pain, constipation, dizziness, weakness and stomach ache. If you experience any allergic or unusual reactions after taking this medicine, report to your doctor immediately.
Warnings
Rosuvastatin,Fenofibrate is contraindicated in patients with known hypersensitivity to rosuvastatin, fenofibrate or any of its components. Also, it should not be used in patients with a history of gallbladder disease including gallstones. It should be used with caution in patients with renal impairment, as it may cause kidney damage. Inform your doctor if you have kidney or liver problems, severe respiratory failure, thyroid problems, continuous muscle pain (such as myopathy or rhabdomyolysis), or if you are drinking heavy amounts of alcohol regularly before starting treatment with Rosuvastatin,Fenofibrate, because it may increase the triglyceride levels in the blood and do not take it unless prescribed by your doctor.
Precautions
This drug is not recommended during pregnancy as it causes harm to the unborn baby. Avoid getting pregnant and breastfeeding during the treatment. Use effective contraception to avoid pregnancy, as it can harm the developing foetus or nursing infant. It is advised to take a low-cholesterol diet and do regular exercises while taking this medication.
Word of Advice
It is advised to avoid foods high in fat, including red meat (beef, lamb, and pork), butter, cheese, sugary drinks, fried foods, and junk foods. Limit alcohol intake while taking Rosuvastatin and Fenofibrate, as alcohol can elevate triglyceride levels. A healthy low-fat diet is recommended, including omega-3 fatty acids, which may help reduce blood cholesterol. Include nutrient-dense foods such as berries, apples, broccoli, brown rice, and tofu. If you vomit after taking the medicine, do not take an additional dose. Take your next dose at the scheduled time. Do not discontinue this medicine without consulting your doctor. Your doctor may conduct laboratory tests to assess the therapy's effectiveness or monitor for unwanted side effects.
References
AstraZeneca UK Ltd, Electronic Medicines Compendium (EMC), [Revised on July 2022] [Accessed on 20th April 2023], https://www.medicines.org.uk/emc/files/pil.6779.pdf Glenmark Pharmaceuticals Europe Limited, Electronic Medicines Compendium (EMC), [Revised on October 2021] [Accessed on 20th April 2023], https://www.medicines.org.uk/emc/files/pil.9971.pdf Zentiva Pharma UK Limited, , Electronic Medicines Compendium (EMC), [Revised on June 2022] [Accessed on 20th April 2023], https://www.medicines.org.uk/emc/files/pil.8870.pdf Goodman & Gilmanâs Pharmacological Basis of Therapeutics, 13th Edition, 2018, 905-909.
Frequently Asked Questions
Whether Rosuvastatin,Fenofibrate can cause kidney damage?
Yes, Rosuvastatin,Fenofibrate can cause kidney damage, so it should be avoided in patients with severe kidney failure or impaired kidney function. Consult your doctor immediately if you notice any early signs and symptoms of kidney damage. These symptoms may include swelling in your legs or feet, decreased urine output, and difficulty breathing.
What should I tell my healthcare provider before taking Rosuvastatin,Fenofibrate?
Inform your physician about all your past medical and medication history, including over-the-counter medicines, and nutritional or vitamin supplements before taking Rosuvastatin,Fenofibrate.
How long do I have to take Rosuvastatin,Fenofibrate?
The duration of your treatment depends on your disease condition and severity. Your doctor will decide your dose, and duration of your treatment.
Is Rosuvastatin,Fenofibrate safe to use during pregnancy?
No, Rosuvastatin,Fenofibrate is not safe to use during pregnancy. Do not take this tablet if you are pregnant. Inform your doctor immediately if you get pregnant while using this medication.
I missed my regular dose of Rosuvastatin,Fenofibrate. What should I do?
If you forget your normal dose of Rosuvastatin,Fenofibrate, then take your dose at the next scheduled time. Do not double the dose to compensate for the dose you missed.