SODIUM BICARBONATE

Background and Date of Approval

Sodium Bicarbonate is an antacid that neutralises gastric acid and raises the pH of gastric contents. It is indicated for indigestion. The medication received U.S. FDA approval on February 27, 2006.

Uses

Sodium bicarbonate is used as an alkalinizing agent in treating ingestion, heartburn, metabolic acidosis, severe diarrhea, and acidity.

How is it administered?

Sodium Bicarbonate Tablet: Take the Sodium Bicarbonate as your physician advises. Do not crush, chew, or open the medicine. Your physician will decide the correct dosage and duration based on age, body weight, and disease condition. Only stop taking the tablet if your doctor advises you to stop. Sodium Bicarbonate Injection: Sodium Bicarbonate will be administered to you by a healthcare professional in a hospital setting. It is usually administered in muscle or vein (intravenous). Your doctor will decide the dose, route of administration, and frequency based on your disease condition and other factors. Sodium Bicarbonate Powder/sachet: Take the Sodium Bicarbonate as your physician advises. Follow the instructions provided by your healthcare professional. Typically, the powder/sachet is dissolved in water and taken orally. It is important to measure the correct dosage and mix it thoroughly before drinking. Your physician will decide the correct dosage and duration based on age, body weight, and disease condition. Only stop taking the tablet if your doctor advises you to stop. Sodium Bicarbonate Syrup Take the Sodium Bicarbonate as your physician advises. Follow the instructions provided by your healthcare professional. Typically, the syrup is taken orally. It is important to measure the correct dosage and mix it thoroughly before drinking. Your physician will decide the correct dosage and duration based on age, body weight, and disease condition. Only stop taking the tablet if your doctor advises you to stop.

Side Effects

The most common side effects of Sodium Bicarbonate are low potassium levels (resulting in muscle twitching and weakness), low blood sugar, high sodium levels (causing increased thirst and urination), acidosis (increased breathing rate), increased blood volume, low calcium levels (muscle contractions), swelling and bleeding, stomach cramps, increased blood pressure, increased potassium in the blood, fluid retention in the lungs. Serious side effects while taking Sodium Bicarbonate are allergic reactions (rash, hives, itching, red, swollen, blistered, or peeling skin).

Warnings

Sodium Bicarbonate should not be consumed if you are allergic to Sodium Bicarbonate or any of its ingredients in the medication. Do not use this injection if you have hypoventilation (slow or shallow breathing), certain blood abnormalities, kidney stones, high blood pressure, high levels of alkali in blood, low levels of calcium, kidney or liver, or heart failure, or if you experience fluid retention.

Precautions

It is important to inform your doctor about these conditions before starting the treatment. During the treatment with this medicine, your healthcare provider may regularly monitor your blood acid levels. Notify your doctor if you are on a low-salt or salt-free diet or intolerant to sucrose, as it contains a small amount of sucrose present in the medication. Before starting the treatment, inform your doctor if you are pregnant, think you may be pregnant, or planning to get pregnant or breastfeeding.

Word of Advice

Patients with liver, heart, or kidney disease should use Sodium Bicarbonate with caution and inform their doctor of all underlying medical conditions. Do not discontinue the medicine without medical advice. Do not take a double dose to compensate for a missed dose. Do not breastfeed while taking Sodium Bicarbonate unless your doctor advises otherwise. Report any serious side effects to your doctor. Your doctor will determine if dose adjustments are necessary. Contact your doctor for further information. Keep out of reach of children and pets. Do not freeze the medicine. Do not store above 25°C. Check the expiry date before use.

References

Martindale pharma, Electronic Medicines Compendium (EMC), [Revised on Aug 2018] [Accessed on 16th June 2023], pil.3697.pdf (medicines.org.uk) Hospira, INC, Food and Drug Administration, [Revised on Aug 2005] [Accessed on 16th June 2023], Sodium Bicarbonate (fda.gov) Sodium bicarbonate; Ingenus Pharmaceuticals; Revised 2021; [Accessed 16th June 2023]; https://dailymed.nlm.nih.gov/dailymed/fda/fdaDrugXsl.cfm?setid=3cb67478-1a51-4e7d-a529-79029655f5d9&type=display WebMD, Sodium bicarbonate, [Accessed 16th June 2023] SODIUM BICARBONATE: Overview, Uses, Side Effects, Precautions, Interactions, Dosing and Reviews (webmd.com) Drugs.com, [Accessed 16th June 2023] Sodium Bicarbonate Tablets Information - Drugs.com

Frequently Asked Questions

How to manage the side effects of Sodium Bicarbonate?

To manage the side effects of Sodium Bicarbonate injection, it is important to follow the guidance of your healthcare provider. If you experience low potassium levels, low blood sugar, high sodium levels, acidosis, or low calcium levels, your doctor may adjust your medication or provide additional treatment. It is advisable to drink plenty of water and maintain proper hydration.

What are the side effects of Sodium Bicarbonate?

Common side effects of Sodium Bicarbonate include low potassium levels (resulting in muscle twitching and weakness), low blood sugar, high sodium levels (causing increased thirst and urination), acidosis (increased breathing rate), increased blood volume, low calcium levels (muscle contractions), swelling and bleeding. It is crucial to consult your doctor for any concerns or persistent side effects.

Can you take Sodium Bicarbonate when pregnant?

Limited information is available on using Sodium Bicarbonate during pregnancy. So consult your medical professional regarding the usage. The potential benefits and risks should be carefully assessed. Your doctor will suggest taking this medicine only if it's necessary.

Can sodium bicarbonate cause high blood pressure?

Sodium bicarbonate is not typically associated with causing high blood pressure. However, excessive sodium intake from any source, including sodium bicarbonate, can elevate blood pressure in sensitive individuals or those with hypertension. Monitoring sodium intake and consulting a healthcare professional are recommended for personalized guidance.

What is the storage temperature of Sodium Bicarbonate?

The storage temperature of Sodium Bicarbonate is to not store above 25°C. Store in the original container. Do not freeze the medicine.

Is it safe to take sodium bicarbonate daily?

Consult a healthcare professional to assess the safety of daily sodium bicarbonate intake and follow recommended dosages to avoid potential side effects and electrolyte imbalances.

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Written By: Muskan Patel, M.Pharm

Reviewed By: Dr. Vishwa Patel, MBBS