TELMISARTAN,AZELNIDIPINE
Background and Date of Approval
Telmisartan + Azelnidipine is indicated for the treatment of hypertension. This combination comprises an angiotensin II receptor antagonist and a calcium channel blocker. Telmisartan works by blocking angiotensin II, a naturally occurring substance responsible for constricting blood vessels and raising blood pressure. Azelnidipine, a calcium channel blocker, relaxes blood vessels, thereby reducing pressure and enhancing blood flow.
Uses
Telmisartan + Azelnidipine treats stage 2 hypertension (high blood pressure). It functions by inhibiting the effects of angiotensin II, causing the blood vessels to relax and decreasing blood pressure.
How is it administered?
Take the Telmisartan + Azelnidipine tablet as your physician advises. Usually, it is taken once a day. Take medicine at a fixed time. Do not crush, chew, or open the medicine. Your physician will decide the correct dosage and duration based on age, body weight, and disease condition. Only stop taking the tablet if your doctor advises you to stop.
Side Effects
The most common side effects of Telmisartan + Azelnidipine are low blood pressure, back pain, sinusitis, and diarrhea. Serious side effects while taking Telmisartan + Azelnidipine are sepsis (blood poisoning) and angioedema (swelling in the deeper layers of the skin).
Warnings
Do not consume Telmisartan + Azelnidipine if you are allergic to Telmisartan, Azelnidipine, and its other ingredients. Also, do not consume if you have severe liver (biliary obstruction) conditions or combined with aliskiren-containing products in patients with diabetes mellitus or renal impairment. Before starting the treatment, inform your doctor if you have any liver, kidney, or heart conditions. Azelnidipine is contraindicated in women who may be pregnant or already pregnant, as well as in combination with certain medications like azole antifungals and HIV protease inhibitors.
Precautions
Avoid abrupt discontinuation of calcium antagonists. Your physician will monitor for excessive blood pressure decrease, hepatic function disorders, and jaundice and adjust the dose if needed. Also, your doctor will discontinue Telmisartan + Azelnidipine if abnormalities occur. Before starting the treatment, inform your doctor if you have a myocardial infarction, arrhythmia, or heart failure. Avoid consuming grapefruit juice while taking the medication.
Word of Advice
Patients with liver disease or heart disease should use Telmisartan + Azelnidipine with caution and inform their doctor of all underlying medical conditions. Do not discontinue the medicine without medical advice. Do not take a double dose to compensate for a missed dose. Inform your doctor if you experience any serious adverse effects. Your doctor will advise if dose adjustments are necessary. Contact your doctor for additional information. Avoid consumption of grapefruit or grapefruit juice. Store out of sight and reach of children and pets. Do not freeze the medicine. Store below 25°C. Always verify the expiry date before use.
References
Glenmark Pharmaceuticals Europe Limite., Electronic medicines compendium (emc), [Revised on November 2019] [ Accessed on 30th May 2023], 13 Product Information (medicines.org.uk) Hetero labs limited, US Food and Drug Administration, [Revised on August 2015] [Accessed on 30th May 2023], 205901Orig1s000lbl.pdf (fda.gov) J. B. Chemicals & pharmaceuticals LTD, [Revised on November 2021] [ Accessed on 30th May 2023], *Azovas-T40-T80_PI_India_November-2021.pdf (jbpharma.com)
Frequently Asked Questions
What is the composition of Telmisartan + Azelnidipine and its uses?
Telmisartan + Azelnidipine is a medication that combines Telmisartan + Azelnidipine and Azelnidipine. It is used to treat high blood pressure.
How to manage the side effects of Telmisartan + Azelnidipine?
To manage the side effects of Telmisartan + Azelnidipine, follow the prescribed dosage, and report side effects promptly. Stay hydrated, and monitor blood pressure regularly. Maintain a healthy lifestyle, and attend follow-up appointments.
Can I dissolve the Telmisartan + Azelnidipine and drink it instead of swallowing it?
No, you should not dissolve the tablet and drink the solution. This medicine was designed to be swallowed whole with water. It's mandatory to follow the instructions provided by your healthcare provider to avoid the side effects of Telmisartan + Azelnidipine.
Are there any serious side effects of Telmisartan + Azelnidipine I should be aware of?
Yes, side effects of Telmisartan + Azelnidipine may include severe allergic reactions and liver or kidney problems. It is mandatory to seek medical attention if you encounter any side effects, such as difficulty breathing, swelling, nausea, and rashes.
Is it safe to consume alcohol while taking Telmisartan + Azelnidipine?
No, it is unsafe to consume alcohol while taking Telmisartan + Azelnidipine. Please speak with your physician for more concerns.