TELMISARTAN,HYDROCHLOROTHIAZIDE,AMLODIPINE
Background and Date of Approval
The U.S. FDA approved the combination of Telmisartan, Hydrochlorothiazide, and Amlodipine for the treatment of hypertension on November 16, 2009. Telmisartan, Hydrochlorothiazide, and Amlodipine belong to the class of medications known as antihypertensives.
Uses
Telmisartan +Hydrocholrthiazide +Amlodipine is primarily used for the treatment of hypertension. Hypertension (high blood pressure) is a medical condition in which blood exerts a force on the artery walls (blood vessels), resulting in heart disease, irregular heartbeat, and other problems.
How is it administered?
Take the Telmisartan +Hydrocholrthiazide +Amlodipine as your physician advises. Do not crush, chew, or open the medicine. Your physician will decide the correct dosage and duration based on age, body weight, and disease condition. Only stop taking the tablet if your doctor advises you to stop.
Side Effects
The most common side effects of Telmisartan +Hydrocholrthiazide +Amlodipine are sleepiness, ankle swelling, nausea, headache, flushing, dizziness, fatigue (tiredness), palpitations, stomach upset, peripheral edema, and mood changes.
Warnings
Telmisartan +Hydrocholrthiazide +Amlodipine should not be consumed if you are allergic to Telmisartan +Hydrocholrthiazide +Amlodipine or any of its ingredients in the medication. Report to your doctor immediately if you have anuria (kidney failure that causes less urine production) and diabetes. It is not recommended for people with hypotension (low blood pressure), liver and kidney disease, heart failure, electrolytes, and metabolic disorders. This medication is not intended to be used during the second and third trimesters of pregnancy, as it reduces fetal renal function and causes harmful effects on the developing fetus.
Precautions
Notify your doctor if you are pregnant, planning to get pregnant, or think you may be pregnant or breastfeeding. Calcium citrate+Vitamin D3+Zinc +Magnesium should be used cautiously in liver patients. Before starting the treatment, inform your physician about pre-existing liver conditions. Avoid consuming alcohol while taking Telmisartan +Hydrocholrthiazide +Amlodipine, as it may cause unpleasant side effects. Do not drive or operate machinery because Telmisartan +Hydrocholrthiazide +Amlodipine can cause dizziness, drowsiness, or tiredness.
Word of Advice
Do not breastfeed while taking Telmisartan, Hydrochlorothiazide, Amlodipine unless your doctor advises. Notify your doctor if you experience any serious side effects. Your medical professional will inform you if you need any dose adjustments. Contact your doctor for more information. It is advised to restrict salt intake in the diet. If you have a history of heart failure and hypotension, monitoring your blood pressure regularly is suggested. Drink plenty of water and fluids to keep yourself hydrated.
References
KD Tripathi, Essentials of Medical Pharmacology, Antihypertensive drugs, 7th edition. 2013, 561-563. Sanofi India Limited, [Accessed on 13th June 2023]; https://www.sanofi.in/dam/jcr:f1d59d7f-bfe7-456b-9f95-02f66fb22cb7/Telsite%20AM%20H%20PI%20June%202018.pdf Accord Healthcare Limited; Electronic Medicines Compendium (EMC), [Revised on January 2022] [Accessed on 13th June 2023], https://www.medicines.org.uk/emc/product/6126/smpc#gref Pfizer labs; US Food and Drug Administration, [ Revised on May 2011] [ Accessed on 13th June 2023], https://www.accessdata.fda.gov/drugsatfda_docs/label/2011/019787s047lbl.pdf Bonchringer Ingelheim Phramaceuticals Inc., US Food and Drug Administration, [ Revised on Oct 2009] [ Accessed on 13th June 2023], https://www.accessdata.fda.gov/drugsatfda_docs/label/2009/022401lbl.pdf
Frequently Asked Questions
Can I use Telmisartan +Hydrocholrthiazide +Amlodipine during pregnancy?
No, Telmisartan +Hydrocholrthiazide +Amlodipine should not be used during pregnancy, especially in the second and third trimesters, because it reduces fetal renal function and increases harmful effects on the developing fetus.
What class of medication is Telmisartan +Hydrocholrthiazide +Amlodipine?
Telmisartan +Hydrocholrthiazide +Amlodipine belongs to a class of medication called antihypertensive medicine.
Is it safe to take Telmisartan +Hydrocholrthiazide +Amlodipine in diabetic patients?
A healthcare professional should assess the safety of taking Telmisartan + Hydrochlorothiazide + Amlodipine in diabetic patients. A doctor should consider the individual's medical history and needs to determine the appropriateness of these medications for managing high blood pressure in diabetic patients.
Who is contraindicated to use Telmisartan +Hydrocholrthiazide +Amlodipine?
Telmisartan +Hydrocholrthiazide +Amlodipine is contraindicated in people with hypersensitivity (allergic reaction) and patients with anuria and severe kidney or liver impairment. It should also be avoided in women in the second and third trimesters of their pregnancy.
Can dizziness be a possible side effect of taking Telmisartan + Hydrochlorothiazide + Amlodipine?
Yes, using Telmisartan+Hydrocholrthiazid+Amlodipine Tablet can cause dizziness. It is advised to avoid driving or operating any heavy machinery while taking this medication. Consult your doctor immediately if you experience any side effects.