TELMISARTAN,METOPROLOL,CILNIDIPINE

Background and Date of Approval

Telmisartan, metoprolol, and cilnidipine is a combination medication approved for medical use in the management of high blood pressure. It belongs to the class of antihypertensive drugs.

Uses

Telmisartan, metoprolol, and cilnidipine are used for hypertension. This medication is recommended when single or dual therapy is not effective. It helps relax the blood vessels by making it easier for the heart to pump blood all over the body, and it lowers the risk of heart attack and stroke.

How is it administered?

Telmisartan, metoprolol, and cilnidipine combination is available in oral dosage tablet form containing telmisartan 40 mg, cilnidipine 10 chew, crush succinate 23.75 mg. Your physician will decide the correct dosage and duration based on age, body weight, and disease condition. It should be consumed as a whole not to chew,crush or bite.

Side Effects

Telmisartan, metoprolol, and cilnidipine can cause side effects like any other medicine. Sometimes it may cause some serious side effects that include swelling of ankles and feet, slow heart rate and hypotension and commonly, people may experience fever, increased potassium levels, tiredness, feeling sleepy, headaches, back pain, difficulty in breathing, stomach upset and nausea.

Warnings

Stopping this medication without proper advice will make the condition worse. It acts by lowering blood pressure and reduces the risk of heart attack and stroke, so don't stop this medication without the proper advice of a doctor.It may cause hypotension and renal impairment, clonidine may lead to severe hypotension and rebound hypertension if discontinued abruptly, and metoprolol may result in bradycardia and bronchospasm. Carefully monitor these side effects and report if you find any discomforts to your physician.

Precautions

Before starting the Telmisartan, metoprolol, and cilnidipine therapy inform your doctor about any kidney or liver-related problems. If you are a breastfeeding mother or planning for pregnancy, you need to inform your doctor before starting this medication. While using this medication, blood pressure should be monitored regularly, and a kidney function test should be performed to note if there are any abnormal changes.

Word of Advice

Inform your doctor of any history of allergic reactions to prevent serious complications. Since this combination can increase potassium levels, avoid potassium-rich foods and potassium supplements. Notify your doctor before starting treatment if you are pregnant or have liver, kidney, or uterine disorders. During treatment, blood pressure requires regular monitoring, and kidney function tests should be performed to check for any abnormal changes.

References

Boehringer Ingelheim Pharmaceuticals, Inc, Electronic medicines compendium (EMC), [Revised on March 2022) [Accessed date 4/11/2022] https://www.medicines.org.uk/emc/files/pil.3164.pdf 2. KD. Tripathi. Antianginal and Other Anti-ischemic Drugs & Drugs Affecting Renin-Angiotensin System. Eighth edition. June 2018, 596 & 536. 3. Torrent Pharmaceuticals Ltd. Telstar N (Telmisartan and Cilnidipine Tablets), [Revised in April 2020], [Accessed on 24/06/2023] https://www.torrentian.com/pisheet/Upload/PI_Sheet/2909.pdF 4. Boehringer Ingelheim Pharmaceuticals, Inc, US Food & Drug Administration, [Revised on 3/5/2011], [Accessed on 24/06/2023], https://www.accessdata.fda.gov/drugsatfda_docs/label/ 2004/020850s011lbl.pdf

Frequently Asked Questions

How can I know my potassium level is high while taking Telmisartan, metoprolol, and cilnidipine?

The doctor will be monitoring the potassium level in the blood. Patients should avoid potassium supplements and a diet which are rich in potassium to prevent the side effects caused by this medication.

Does Telmisartan metoprolol and cilnidipine cause hypotension?

This medication may cause hypotension in some patients because metoprolol is a beta blocker that slows down the heart rate. Blood pressure should be monitored regularly while taking this medication.

What are the active ingredients of Telmisartan, metoprolol, and cilnidipine?

This medication consists of telmisartan, metoprolol, and cilnidipine. Cilnidipine is the calcium channel blocker, telmisartan is the angiotensin receptor blocker, and metoprolol lowers the heart rate. This medication is used when single or dual therapy is not effective.

Can Telmisartan, metoprolol, and cilnidipine be given to diabetes patients?

Yes, this medication can be given in diabetic patients, but blood glucose levels should be monitored regularly as it causes a decrease in blood glucose levels.

Can Telmisartan, metoprolol, and cilnidipine cause swelling as a side effect?

Telmisartan, metoprolol, and cilnidipine cause swelling in the ankles, and hence it is advised to keep the legs on the table in the raised position to reduce the swelling.

Written By: Muskan Patel, M.Pharm

Reviewed By: Dr. Vishwa Patel, MBBS