TELMISARTAN,NEBIVOLOL

Background and Date of Approval

Telmisartan and nebivolol is approved for medical use in the treatment of hypertension (high blood pressure).

Uses

Telmisartan + nebivolol is used to treat hypertension.

How is it administered?

Telmisartan + nebivolol is available as respules for inhalation in nebulizer. Your physician will decide the correct dosage and duration based on age, body weight, and disease condition.

Side Effects

The common side effects that are experienced while you are on the treatment with telmisartan + nebivolol are headache, dizziness, tiredness, slow heartbeat, weakness, increased potassium level in the blood, decreased blood pressure, cold extremities, an unusual itching or tingling feeling,diarrhea, constipation, nausea, shortness of breath, swollen hands or feet, stomach upset, nightmares, forgetfulness, difficulty falling asleep. If you have angioedema (swelling of skin), allergic reaction, with a skin eruption speak with your doctor immediately.

Warnings

Before starting treatment, inform your doctor if you have allergies to Telmisartan or Nebivolol, a history of heart disease, diabetes, low blood pressure, Raynaud's disease, or Prinzmetal angina. Before treatment with Telmisartan+ Nebivolol, let your physician know if you are experiencing any allergic reaction to Telmisartan or Nebivolol and its ingredients.

Precautions

Report to your physician if you have kidney or severe liver diseases, heart rhythm problems, low blood pressure, elevated potassium level in the blood, raised aldosterone level, diabetes, asthma, and renal artery stenosis (narrowing of the blood vessels to one or both kidneys). Hence, your doctor may regularly monitor your blood pressure, electrolytes, and potassium level in your blood at regular intervals. It should not be given to children less than 12 years of age.

Word of Advice

Regular blood pressure monitoring is important during treatment with Telmisartan and Nebivolol. Potassium and electrolyte levels should be checked periodically whilst taking this combination to prevent complications. Rise slowly from a lying or sitting position, as this medicine may cause dizziness. A low-salt diet combined with regular exercise may improve treatment outcomes. Smoking and alcohol consumption should be avoided during this therapy.

References

KD Tripathi, Essentials of Medical Pharmacology, Antihypertensive Drugs, 7th Edition, 2018, 561-564. Accord Healthcare Limited., Electronic Medicines Compendium (EMC), [Revised on April 2022] [Accessed 19th Sept 2023] https://www.medicines.org.uk/emc/files/pil.5828.pdf Boehringer Ingelheim Ltd., Electronic Medicines Compendium (EMC), [Revised on April 2021] [Accessed on 19th Sept 2023], https://www.medicines.org.uk/emc/files/pil.3165.pdf Boehringer Inhelheim International GmbH & Co., US Food and Drug Administration, [ Revised on May 2011] [ Accessed on 19th Sept 2023], https://www.accessdata.fda.gov/drugsatfda_docs/label/2004/020850s011lbl.pdf

Frequently Asked Questions

Is children use Telmisartan+ Nebivolol?

No, Telmisartan+ Nebivolol is not recommended for children less than 12 years of age.

What happens when I stop taking Telmisartan+ Nebivolol?

Sudden withdrawal of Telmisartan+ Nebivolol may raise your blood pressure and increase the risk of heart failure. Hence, it is necessary to consult your doctor before withdrawing this medication.

What happens if I take too much Telmisartan+ Nebivolol?

If you take more Telmisartan+ Nebivolol, that may cause slow heartbeat (bradycardia), low blood pressure with fainting (hypotension), breathlessness such as in asthma (bronchospasm), and acute heart failure.

Is Telmisartan+ Nebivolol safe during pregnancy?

No, Telmisartan+ Nebivolol should not be used during pregnancy because it may cause harmful effects on the developing fetus.

Can Telmisartan+ Nebivolol cause shortness of breath?

Yes, Telmisartan+ Nebivolol can cause shortness of breath in some people. You must inform your physician if these symptoms disturb or worsen you.

Written By: Muskan Patel, M.Pharm

Reviewed By: Dr. Vishwa Patel, MBBS