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6 MP 50mg Tablet
Salt Composition: MERCAPTOPURINE
- Manufacturer: ZYDUS CADILA
- Pack Size: 10 TABLET(s) IN A STRIP
- Dosage Form: TABLET
- Strength: 50MG
- Prescription Required
- Storage: Store 6 MP 50mg Tablet in the original package at room temperature (15°C to 25°C). Keep it out of reach from children.
₹45.00₹56.06
Inclusive of all taxes
Product Introduction
6 MP 50mg Tablet is an anti-cancer drug belonging to the class of purine antagonists. It contains the active ingredient Mercaptopurine and is used in the treatment of acute lymphoblastic leukaemia (ALL). ALL is a type of cancer affecting the blood and bone marrow, characterised by overproduction of immature white blood cells known as lymphoblasts, which are unable to function properly and accumulate in the bone marrow and blood.
Before receiving any vaccination, inform your doctor or nurse. Do not receive live vaccines (such as polio, measles, mumps and rubella) while taking this medicine unless your doctor advises it is safe to do so, as some vaccines may cause infection during treatment. Do not receive yellow fever vaccine while taking this medicine as it may lead to serious illness.
Your doctor may request blood and urine tests to monitor kidney function and measure uric acid levels. Uric acid is a natural substance produced in your body; levels may rise during treatment with this medicine. High uric acid levels may damage your kidneys, and your doctor may adjust your dose based on these test results.
Lower initial doses are advisable in patients with impaired renal function due to slower elimination of the drug and metabolites and greater cumulative effect. Dosage reduction should be considered in patients with impaired hepatic function.
During treatment, your doctor may periodically monitor your white blood cell counts, platelets, blood sugar, electrolytes and kidney parameters to prevent serious complications. Inform your doctor if you have been diagnosed with liver disorders, heart failure, high blood cholesterol levels or hypertension before starting this treatment.
This medicine has the potential to cause liver problems, and your doctor will carry out weekly liver function tests while you are taking this drug. Report to your doctor if you experience hypersensitive reactions such as itchy skin or rashes while taking this medicine.
This tablet contains lactose as an inactive ingredient. If your body is unable to digest lactose (a sugar found in milk and dairy products), it may cause symptoms such as bloating and abdominal pain. Inform your doctor before starting this therapy if you have lactose intolerance.
Uses
Acute lymphoblastic leukaemia
How it works
This medicine functions by interfering with DNA and RNA function in cancer cells, inhibiting nucleotide synthesis, suppressing the immune system, and activating enzymes that can kill cancer cells. It is typically used in combination with other chemotherapy drugs to enhance its effectiveness.
How to Use
Your doctor will decide the dose and duration of 6 MP 50mg Tablet based on the disease condition and other factors. Always take this medicine as prescribed by your doctor. Take the tablet at the same time everyday, with or without food. Do not chew, crush, or break the tablet. Swallow the whole tablet with water. You must take these tablets at least 1 hour before or 2 hours after having milk or dairy products.
Side Effects
Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them. Common Nausea, vomiting Anemia Fever or infection (sore throat, sore mouth, or urinary problems) Unexplained bruising or bleeding Low white blood cell and platelet count
Expert Tips
Consult your physician if you experience fever, sore throat, jaundice, nausea, vomiting, signs of local infection, bleeding from any site, or symptoms suggestive of anaemia. Women of childbearing potential should avoid becoming pregnant. This medicine is not recommended for pregnant women as it may cause fetal harm. Consult your doctor if you are pregnant or planning for pregnancy during treatment. This medicine passes into breast milk; breastfeeding is not recommended during treatment. Limit alcohol intake or avoid it altogether during treatment. While taking this drug, you are more sensitive to the sun and UV light. Limit your exposure to sunlight and UV light, wear protective clothing, and use a sun cream with a high sun protection factor (SPF). Low blood sugar (sweating more than usual, nausea, dizziness, confusion) has sometimes been observed in children, mainly in children under the age of six or with a low body mass index. Speak with your child's doctor if this occurs.
References
- Aspen Pharma Trading Limited, Electronic medicines compendium (emc), [ Revised on August 2019] (Accessed: April 6, 2023), https://www.medicines.org.uk/emc/files/pil.4655.pdf
- Purinethol® (mercaptopurine) 50-mg scored tablets caution. Available at: https://www.accessdata.fda.gov/drugsatfda_docs/label/2011/009053s032lbl.pdf (Accessed: April 6, 2023).
- Mercaptopurine - HPRA. Available at: https://www.hpra.ie/img/uploaded/swedocuments/792acbf1-e5ab-4598-8f95-30d1e2ddffcc.pdf (Accessed: April 6, 2023).
- Goodman & Gilmanâs, The Pharmacological Basis of Therapeutics, Cytotoxic agents, 12th edition, 2011, 1701 - 1702.
- KD Tripathi, Essentials of Medical Pharmacology, Anticancer drugs, 7th edition, 2013, 863.
Safety Advice
Pregnancy: unsafe 6 MP 50mg Tablet is not recommended for pregnant women as it may cause fetal harm. Consult your doctor if you are pregnant or planning for pregnancy during the treatment.
Lungs: Consult your doctor It is not known whether 6 MP 50mg Tablet can be administered to patients with lung problems. Consult your doctor if you have any lung diseases before starting the treatment.
Breastfeeding: unsafe 6 MP 50mg Tablet should not be taken if you are breastfeeding as it passes into breast milk. You need to tell your physician if you are breastfeeding before taking this medicine.
Disclaimer
The information provided on this page is intended for general informational purposes only and should not be considered as medical advice. Always consult a qualified healthcare professional before starting, stopping, or changing any medication. Self-medication can be harmful. Med For Rare does not endorse self-diagnosis or self-treatment.