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Abakast L Tablet

Salt Composition: ABACAVIR,LAMIVUDINE

₹1969.00₹2718.75

Inclusive of all taxes

Abakast L Tablet

Categories: Infectious Disease

Conditions: HIV/AIDS

Product Introduction

Abakast L Tablet

Abakast L Tablet is an antiretroviral medication containing the active constituents Abacavir and Lamivudine. Both medications belong to a class of drugs called nucleoside reverse transcriptase inhibitors (NRTIs) and are often used in combination with other antiretroviral drugs as part of highly active antiretroviral therapy (HAART) or combination antiretroviral therapy (cART). It is used to treat HIV-1 infection. HIV-1 is a virus known as the Human immunodeficiency virus, which targets and damages immune system cells, ultimately weakening the body's defence against infections. If left untreated, it can result in death. While this medication does not offer a complete cure, it effectively lowers the virus levels in your body and increases the count of CD4 cells in your bloodstream. These cells play a crucial role in assisting your body's fight against infections. Abakast L Tablet is usually given with other medicines to treat HIV infection. Combining Abakast L Tablet with didanosine is not advisable, as it could increase the chances of experiencing didanosine toxicity. Before taking this medication, it is important to inform your doctor if you have any liver disease, including hepatitis B or C, kidney disease, heart problems, high blood pressure, high cholesterol, diabetes, or if you are overweight. It is crucial not to share personal items like razors or toothbrushes with others, and breastfeeding should be avoided. Your doctor can provide guidance on practising safe sex. The administration of this medicine can potentially result in lactic acidosis, which involves the accumulation of acid in the bloodstream. In patients with advanced HIV infection and severely compromised immune systems, initiating antiretroviral therapy, including Abakast L Tablet, may lead to an inflammatory response known as immune reconstitution inflammatory syndrome. Close monitoring is necessary in such cases.

Uses

Treatment of HIV-1 infection

How it works

Abakast L Tablets work by inhibiting the reverse transcriptase enzyme, which is necessary for the replication of HIV. By blocking this enzyme, the drugs help to reduce the viral load in the body, slow down the progression of HIV infection, and improve the immune system's function.

How to Use

To use Abakast L Tablets, follow the prescribed dosage and instructions provided by your healthcare provider. Take the medications as directed, usually orally, with or without food. Do not skip doses or stop taking them without consulting your healthcare provider. Consult your healthcare provider or pharmacist for guidance if you have any questions or concerns.

Side Effects

Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them. Serious Lactic acidosis (breathing difficulties along with weakness in limbs, stomach pain, vomiting, drowsiness) Liver problems (yellowing of whites of eyes and skin, urine turns dark, light-colored stools) Severe allergic reactions (fever, rash, nausea, diarrhea, shortness of breath) Changes in the immune system Changes in body fats (lipodystrophy) Common Headache Nausea Diarrhea Fatigue Insomnia Abdominal pain Muscle or joint pain Skin rash

Expert Tips

Follow the prescribed dosage and instructions for Abakast L Tablet. Undergo genetic screening for hypersensitivity reactions and seek immediate medical attention if symptoms develop. Monitor for lactic acidosis, check liver function regularly, and adjust doses if renal impairment is present. Be alert to immune reconstitution inflammatory syndrome, symptoms of pancreatitis, and changes in body fat distribution. Account for potential drug interactions and discuss use during pregnancy and breastfeeding with your healthcare provider. Use in elderly patients and children requires special consideration. Consistent adherence and open communication with your healthcare team support safe use of this medication.

References

  1. KD Tripathi, Essentials of Medical Pharmacology, Antiviral drugs, 7th edition, 2013, 807-808.
  2. Goodman & Gilman’s, The Pharmacological Basis of Therapeutics, Antiretroviral agents and treatment of HIV infection, 12th edition, 2011, 1635-1636.
  3. Lupin Healthcare (UK) Limited, Electronic medicines compendium (EMC), [ Revised on April 2023] [ Accessed on 27th May 2023], https://www.medicines.org.uk/emc/landing/status=1
  4. ViiV Healthcare, US Food, and Drug Administration, [ Revised on May 2019] [ Accessed on 27th May June 2023], https://www.accessdata.fda.gov/drugsatfda_docs/pepfar/090519PI.pdf

Safety Advice

Pregnancy: unsafe Abakast L Tablets may cause harm to an unborn baby. Inform your doctor if you are pregnant or planning to get pregnant before taking it. The doctor will explain the potential risks and benefits.

Lungs: Consult your doctor It is important to discuss your specific lung condition with your healthcare provider, as they can provide personalized advice based on your medical history and individual needs.

Breastfeeding: unsafe Breastfeeding is not recommended because the viral infection can pass through breast milk while taking Abakast L Tablets.

Disclaimer

The information provided on this page is intended for general informational purposes only and should not be considered as medical advice. Always consult a qualified healthcare professional before starting, stopping, or changing any medication. Self-medication can be harmful. Med For Rare does not endorse self-diagnosis or self-treatment.

Written By: Muskan Patel, M.Pharm

Reviewed By: Dr. Vishwa Patel, MBBS