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Acopheno Tablet

Salt Composition: MYCOPHENOLATE MOFETIL

₹298.00₹787.50

Inclusive of all taxes

Acopheno Tablet

Categories: Cardiology

Conditions: Transplant

Product Introduction

Acopheno Tablet is an immunosuppressant containing mycophenolate mofetil as the active ingredient. It is classified as an inosine monophosphate dehydrogenase (IMPDH) inhibitor and is used to prevent organ rejection in patients who have undergone organ transplantation, including kidney, heart, or liver. The medicine is administered as part of combination immunosuppressive therapy.

This medication is contraindicated in pregnancy due to the risk of birth defects and miscarriage. It should not be used in pregnant women unless no suitable alternatives exist and the potential benefits justify the risks. Women capable of becoming pregnant are advised to use effective contraception during treatment to prevent pregnancy.

Live vaccines must not be administered to patients taking Acopheno Tablet, as vaccine effectiveness may be reduced and the risk of infection increased. Patients should not donate blood during treatment and for at least six weeks after stopping treatment to allow adequate clearance of the medication from the body.

Do not take this medicine if you are allergic to mycophenolate mofetil or any other ingredients. Inform your doctor of any pre-existing liver or heart disease before starting treatment. As this drug suppresses immune function, it may increase the risk of skin cancer. Patients should take measures to limit sunlight and ultraviolet (UV) light exposure.

Seek immediate medical attention if you develop bruising under the skin, fever, unexplained tiredness, dizziness, yellowing of the skin or eyes, vision impairment, reduced urine output, or seizures after taking this medicine.

Acopheno Tablet is an immunosuppressive medication that may affect infant immune system development and should be avoided during breastfeeding. In certain situations, alternative medications with a more favourable safety profile during breastfeeding may be considered. Acopheno Tablet pricing varies by location and retailer.

Uses

Acopheno tablet uses are: Prevent organ transplant rejections

How it works

Acopheno Tablet works by inhibiting the enzyme inosine monophosphate dehydrogenase (IMPDH) and reducing the production of guanosine nucleotides. MMF specifically affects the proliferation of activated T and B lymphocytes. These lymphocytes are key players in the immune response that can lead to the rejection of a transplanted organ.

How to Use

It is an orally available prescription drug. Your physician will decide the dose and duration of the treatment based on your disease condition, severity, and other factors. Always take Acopheno Tablet as prescribed by your doctor. Do not open, crush, break, or chew the medicine.

Side Effects

Acopheno tablet side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them. Serious Infections, fever, or sore throat Unusual bleeding or bruising Low blood cell count Severe allergic reactions Common Higher risk of developing lymphoma and other cancers Nausea, abdominal pain Diarrhea Constipation Loss of appetite Shortness of breath Weight loss Increased heartbeat Headache Blood pressure problem Anaemia

References

  1. Roche Products Limited, European Medicine Consortium (EMC), [Revised on April 2022],[Accessed on 25/05/2023], https://www.medicines.org.uk/emc/files/pil.1103.pdf
  2. Genentech USA, Inc., [ Revised on Oct 2021] [ Accessed on 25/05/2023], https://www.gene.com/download/pdf/cellcept_prescribing.pdf
  3. S.E. Marshall, Immunological Factors in Disease, Davidson's Principles and Practice of Medicine, 22nd Edition, 2014, 71-96.
  4. KD Tripathi, Immunosuppressant Drugs, Essentials of Medical Pharmacology, 8th Edition, 2019,.937-945.
  5. Goodman & Gilman's, The Pharmacological Basis of Therapeutics, Inflammation, Immunomodulation, and Hematopoiesis, 12th Edition, 2011, 1014.

Safety Advice

Pregnancy: unsafe Acopheno Tablet is known to have harmful effects on the developing fetus and is generally not prescribed for use during pregnancy unless the benefits outweigh the risks.

Lungs: Consult your doctor Acopheno Tablet should be cautiously administered in patients with lung diseases. Dose adjustments are necessary. Inform your physician if you have lung problems before initiating the therapy.

Breastfeeding: unsafe Acopheno Tablet is not recommended for breastfeeding mothers because small amounts of the drug can pass into the mother's milk and affect the nursing baby.

Disclaimer

The information provided on this page is intended for general informational purposes only and should not be considered as medical advice. Always consult a qualified healthcare professional before starting, stopping, or changing any medication. Self-medication can be harmful. Med For Rare does not endorse self-diagnosis or self-treatment.

Written By: Muskan Patel, M.Pharm

Reviewed By: Dr. Vishwa Patel, MBBS