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Acozolo 20mg Capsule

Salt Composition: TEMOZOLOMIDE

₹424.00₹2957.81

Inclusive of all taxes

Categories: Oncology

Conditions: Anti Cancer

Product Introduction

Acozolo 20mg Capsule contains the active ingredient temozolomide. It is an antitumor agent indicated for the treatment of brain tumours, such as glioblastoma multiforme in adults and malignant glioma, including glioblastoma multiforme or anaplastic astrocytoma in patients older than three years. Glioblastoma and anaplastic astrocytoma are the most common and aggressive brain tumours with low survival rates. Anaplastic astrocytoma is treated with Acozolo 20mg Capsule or radiotherapy following biopsy, whereas glioblastoma multiforme is managed with a combination of radiotherapy and Acozolo 20mg Capsule, continued as maintenance therapy.

Common side effects associated with Acozolo 20mg Capsule include nausea, vomiting, dizziness, diarrhoea, constipation, hair loss, rashes, tiredness, frequent urination, vision and hearing problems, elevated blood glucose levels, muscle damage, pain in muscles and joints, memory loss, coordination problems, infections, sleep disturbances and weight loss. Inform your doctor if any of these symptoms occur or persist.

Inform your physician if you are allergic to temozolomide or any ingredients in Acozolo 20mg Capsule. Before commencing treatment, advise your doctor if you have hepatitis B infection, anaemia, low platelet count, low red blood cell and white blood cell levels, blood clotting disorders, or any liver or kidney dysfunction. Your physician will conduct regular monitoring of white blood cell and platelet counts. This medication is contraindicated in pregnancy and lactation. Both women and men should use appropriate birth control measures to prevent pregnancy and to avoid fathering a child. Acozolo 20mg Capsule pricing varies by location and retailer.

Uses

Acozolo 20mg uses are: Treatment of newly diagnosed glioblastoma multiforme. Treatment of refractory anaplastic astrocytoma

How it works

Acozolo 20mg Capsule acts by inhibiting the production of genetic material (DNA and RNA) of the cancer cells, which results in preventing their cell growth and multiplication, thereby preventing cancer spread to other parts of the body.

How to Use

Use as directed by your physician. Your physician will prescribe an adequate dose according to your height and weight. Swallow the capsule whole with a glass of water, on an empty stomach. Do not open, crush or chew the capsule and avoid contact of the open capsules with your skin.

Side Effects

Acozolo 20mg side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them. Serious: Secondary cancer like myelodysplastic syndrome and myeloid leukemia. Severe Allergic reactions Inflammation and fluid buildup in lungs Blood clot in lungs or legs Liver toxicity Convulsions Fever and chills Severe headache Uncontrolled bleeding Common: Hair loss Rashes Tiredness Nausea, vomiting and diarrhea Constipation High blood sugar levels Dizziness, impaired sensation, tingling sensation, abnormal taste Vision and Hearing problem Frequent urination Muscle damage, pain in muscles and joints Weight changes Infections and wounds Amnesia Abnormal blood cell counts Loss of appetite Sleep problems Memory loss Difficulty concentrating, changes in mental status and alertness Coordination problems

References

  1. 1. Sun Pharmaceutical Industries, Electronic Medicines Compendium (EMC) [Revised on Feb 2022] [Accessed on 21 Nov 2022] https://www.medicines.org.uk/emc/files/pil.5318.pdf 2. Pfizer, US Food and Drug Administration, [Revised on Sep 2015] [Accessed on 21 Nov 2022] https://www.accessdata.fda.gov/drugsatfda_docs/label/2016/021029s031lbl.pdf 3. Neha Singh et al., Mechanisms of temozolomide resistance in glioblastoma - a comprehensive review, Cancer Drug Resist; Published on Mar 2021; Accessed on 21/09/2022; https://cdrjournal.com/article/view/3779 4. Zerong Tian et al., Glioblastoma and Anaplastic Astrocytoma: Differentiation Using MRI Texture Analysis, Front. Oncol., Published on Sep 2019; Accessed on 21/09/2022; https://www.frontiersin.org/articles/10.3389/fonc.2019.00876/full

Safety Advice

Pregnancy: unsafe Acozolo 20mg Capsule is unsafe to use during pregnancy as it may cause fetal harm. It should not be used unless prescribed by your physician. Women with childbearing potential should use effective contraceptive precautions for at least 6 months following the completion of treatment.

Lungs: Consult your doctor Inform your physician before taking Acozolo 20mg Capsule if you have if you have any lung conditions.

Breastfeeding: unsafe Acozolo 20mg Capsule is unsafe to use during breastfeeding as it passes through breast milk and harm the baby. Consult your physician for advice before breastfeeding.

Disclaimer

The information provided on this page is intended for general informational purposes only and should not be considered as medical advice. Always consult a qualified healthcare professional before starting, stopping, or changing any medication. Self-medication can be harmful. Med For Rare does not endorse self-diagnosis or self-treatment.

Written By: Muskan Patel, M.Pharm

Reviewed By: Dr. Vishwa Patel, MBBS