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Acozolo 250mg Capsule
Salt Composition: TEMOZOLOMIDE
- Manufacturer: ACCORD PHARMA
- Pack Size: 5 CAPSULE(s) IN A STRIP
- Dosage Form: CAPSULE
- Strength: 250MG
- Prescription Required
- Storage: Keep Acozolo 250mg Capsule out of sight and reach of children. Store protected from light and moisture. Do not store above 25°C.Use as directed by your physician. Your physician will prescribe an adequate dose according to your height and weight. Swallow the capsule whole with a glass of water, on an empty stomach. Do not open, crush or chew the capsule and avoid contact of the open capsules with your skin.
₹1909.00₹23925.00
Inclusive of all taxes
Product Introduction
Acozolo 250mg Capsule contains the active ingredient temozolomide. It is an antitumor agent prescribed to treat brain cancers including glioblastoma multiforme in adults and malignant glioma in patients older than three years. Malignant glioma encompasses glioblastoma multiforme and anaplastic astrocytoma. Glioblastoma and anaplastic astrocytoma are aggressive brain cancers associated with low survival rates. Anaplastic astrocytoma is managed with Acozolo 250mg Capsule or radiotherapy following biopsy. Glioblastoma multiforme is treated with concurrent radiotherapy and Acozolo 250mg Capsule, followed by maintenance therapy.
Common side effects associated with Acozolo 250mg Capsule include nausea, vomiting, dizziness, diarrhoea, constipation, hair loss, rashes, fatigue, frequent urination, vision and hearing problems, elevated blood glucose levels, muscle damage, myalgia and arthralgia, memory loss, coordination problems, infections, sleep disturbances and weight loss. Inform your doctor if any of these symptoms develop or persist.
Inform your physician if you are allergic to temozolomide or any components of Acozolo 250mg Capsule. Before commencing treatment, notify your doctor of hepatitis B infection, anaemia, low platelet count, low levels of red blood cells and white blood cells, blood clotting disorders, or any hepatic or renal impairment. Your physician will monitor white blood cell and platelet counts regularly.
Avoid Acozolo 250mg Capsule if you are pregnant or breastfeeding. Both women and men should use effective contraception to prevent pregnancy and fathering of a child.
Uses
Treatment of newly diagnosed glioblastoma multiforme. Treatment of refractory anaplastic astrocytoma
How it works
Acozolo 250mg Capsule acts by inhibiting the production of genetic material (DNA and RNA) of the cancer cells, which results in preventing their cell growth and multiplication, thereby preventing cancer spread to other parts of the body.
How to Use
Use as directed by your physician. Your physician will prescribe an adequate dose according to your height and weight. Swallow the capsule whole with a glass of water, on an empty stomach. Do not open, crush or chew the capsule and avoid contact of the open capsules with your skin.
Side Effects
Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them. Serious: Secondary cancer like myelodysplastic syndrome and myeloid leukemia. Severe Allergic reactions Inflammation and fluid buildup in lungs Blood clot in lungs or legs Liver toxicity Convulsions Fever and chills Severe headache Uncontrolled bleeding Common: Hair loss Rashes Tiredness Nausea, vomiting and diarrhea Constipation High blood sugar levels Dizziness, impaired sensation, tingling sensation, abnormal taste Vision and Hearing problem Frequent urination Muscle damage, pain in muscles and joints Weight changes Infections and wounds Amnesia Abnormal blood cell counts Loss of appetite Sleep problems Memory loss Difficulty concentrating, changes in mental status and alertness Coordination problems
Expert Tips
It is advised to use effective birth control for both men and women taking Acozolo 250mg Capsule. Women of reproductive potential must use effective contraception during and after six months of therapy. Male patients receiving Acozolo 250mg Capsule treatment should refrain from fathering children and should use reliable contraception during and for three months following the treatment. Your doctor could suggest routine blood tests to check your electrolyte levels, blood cell count, and liver function.
References
- 1. Sun Pharmaceutical Industries, Electronic Medicines Compendium (EMC) [Revised on Feb 2022] [Accessed on 21 Nov 2022] https://www.medicines.org.uk/emc/files/pil.5318.pdf 2. Pfizer, US Food and Drug Administration, [Revised on Sep 2015] [Accessed on 21 Nov 2022] https://www.accessdata.fda.gov/drugsatfda_docs/label/2016/021029s031lbl.pdf 3. Neha Singh et al., Mechanisms of temozolomide resistance in glioblastoma - a comprehensive review, Cancer Drug Resist; Published on Mar 2021; Accessed on 21/09/2022; https://cdrjournal.com/article/view/3779 4. Zerong Tian et al., Glioblastoma and Anaplastic Astrocytoma: Differentiation Using MRI Texture Analysis, Front. Oncol., Published on Sep 2019; Accessed on 21/09/2022; https://www.frontiersin.org/articles/10.3389/fonc.2019.00876/full
Safety Advice
Pregnancy: unsafe Acozolo 250mg Capsule is unsafe to use during pregnancy as it may cause fetal harm. It should not be used unless prescribed by your physician. Women with childbearing potential should use effective contraceptive precautions for at least 6 months following the completion of treatment.
Lungs: Consult your doctor Inform your physician before taking Acozolo 250mg Capsule if you have if you have any lung conditions.
Breastfeeding: unsafe Acozolo 250mg Capsule is unsafe to use during breastfeeding as it passes through breast milk and harm the baby. Consult your physician for advice before breastfeeding.
Disclaimer
The information provided on this page is intended for general informational purposes only and should not be considered as medical advice. Always consult a qualified healthcare professional before starting, stopping, or changing any medication. Self-medication can be harmful. Med For Rare does not endorse self-diagnosis or self-treatment.