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Actemra 162mg Injection
Salt Composition: TOCILIZUMAB
- Manufacturer: CIPLA LTD
- Pack Size: 1 PREFILLED SYRINGE(s) OF 0.9ML
- Dosage Form: INJECTION
- Strength: 162MG
- Prescription Required
- Cold Chain
- Prepaid Only. Non-Returnable.
- Storage: Protect from light and moisture Store actemra medication at 2°C - 8°C Keep children away from the sight and reach of this medication.
₹18534.00₹23168.00
Inclusive of all taxes
Product Introduction
Actemra 162mg injection contains tocilizumab, a monoclonal antibody derived from specific immune cells. It is indicated for moderate to severe active rheumatoid arthritis (RA) in patients with inadequate response to other rheumatoid drugs, giant cell arteritis, systemic juvenile idiopathic arthritis (sJIA) in children, and polyarticular juvenile idiopathic arthritis (pJIA) in children aged 1 year and above, where it reduces pain and swelling in one or more joints.
Actemra 162mg injection is contraindicated in children with known allergic reactions to tocilizumab or its ingredients and in patients with severe infections. Patients should inform their doctor before treatment if they have a history of allergic reactions (difficulty breathing, chest tightness, rash, itching, hives, swelling of lips, tongue, or face), short- or long-term infection, tuberculosis, intestinal ulcers, diverticulitis (small bulging pouches in the digestive tract), liver disease, cancer, kidney function impairment, or persistent headaches. Children with a history of macrophage activation syndrome (activation and uncontrolled proliferation of specific blood cells) require careful monitoring. The elderly population has increased susceptibility to infections compared to the general population and requires cautious management. Patients planning pregnancy, those who may be pregnant, or those who are breastfeeding should inform their doctor before commencing treatment.
Uses
The actemra injection uses are: Rheumatoid arthritis Giant cell arteritis (GCA) Polyarticular Juvenile Idiopathic Arthritis (pJIA) Systemic Juvenile Idiopathic Arthritis (sJIA) Cytokine release syndrome
How it works
Actemra injection inhibits the function of a particular protein known as interleukin-6, which plays a role in the body's inflammatory responses. By blocking this protein, it can help decrease inflammation within your body.
How to Use
Actemra injection 162mg will be administered to you by a healthcare professional in a hospital setting. It is usually administered in the vein (intravenous). Your doctor will decide the dose, route of administration, and frequency based on your disease condition and other factors.
Side Effects
Side effects are unwanted symptoms caused by medicines. Even though all medicines cause side effects, not everyone gets them. Serious Allergic reaction (difficulty with breathing, chest tightness, rash, itching, hives, swelling in the lips, tongue, or face) Fever and chills Mouth or skin blisters Stomach ache Common Upper respiratory tract infections (cough, blocked nose, runny nose, sore throat and headache) High blood fat (cholesterol) levels Injection site reactions. Lung infection (pneumonia) Shingles (herpes zoster) Cold sores (oral herpes simplex), blisters Eye infection (conjunctivitis) Headache, dizziness, high blood pressure Mouth ulceration, stomach pain Fluid retention (edema) in the lower legs, weight increase Cough, shortness of breath Low white blood cell counts (neutropenia, leucopenia) Abnormal liver function tests (increased transaminases) Increased bilirubin shown by blood tests Low fibrinogen levels in the blood (a protein involved in blood clotting).
Expert Tips
Talk to your doctor if you have recently been vaccinated or are planning a vaccination because a certain vaccination (Live vaccine) should not be given while taking actemra 162mg injection. Your doctor will advise you to check the blood if you have low white blood cells, platelets, or elevated liver enzymes before giving you the medicine.
References
- Roche Products Limited, Electronic Medicines Compendium (EMC), [Revised on Apr 2020] [Accessed on 26th Sep 2023], https://www.medicines.org.uk/emc/files/pil.13280.pdf
- Genentech, Inc., US Food and Drug Administration, [Revised on Aug 2017] [Accessed on 26rd Sep 2021], https://www.accessdata.fda.gov/drugsatfda_docs/label/2017/125276s114lbl.pdf
- Ahmed A. Negm & Daniel E. Furst, Nonsteroidal Anti-Inflammatory Drugs, Disease-Modifying Antirheumatic Drugs, Nonopioid Analgesics, & Drugs Used in Gout, Langeâs Basic & Clinical Pharmacology, 14th Edition, 2018, 642-666.
Safety Advice
Pregnancy: Consult your doctor Consult your healthcare provider if you plan to get pregnant. However, Actemra 162mg injection has not been given to expectant mothers, and it should only be used when the projected advantages outweigh any possible hazards to the fetus.
Lungs: Consult your doctor It is unknown whether Actemra 162mg injection is safe for patients with lung problems. Inform your physician if you have any lung disease before starting the treatment. Contact your doctor if you experience any lung-related symptoms.
Breastfeeding: Consult your doctor It is unknown whether actemra 162mg injection is excreted in breast milk. So, before starting the treatment, inform your doctor if you are breastfeeding. Consult your doctor for more information.
Disclaimer
The information provided on this page is intended for general informational purposes only and should not be considered as medical advice. Always consult a qualified healthcare professional before starting, stopping, or changing any medication. Self-medication can be harmful. Med For Rare does not endorse self-diagnosis or self-treatment.