Actemra 200mg Injection

Actemra 200mg injection contains tocilizumab, a monoclonal antibody derived from specific immune cells. It is indicated for moderate to severe active rheumatoid arthritis (RA) in patients with inadequate response to other rheumatoid drugs, giant cell arteritis affecting arteries, systemic juvenile idiopathic arthritis (sJIA) in children, and polyarticular juvenile idiopathic arthritis (pJIA) in paediatric patients aged 1 year and above, where it addresses pain and swelling in one or more joints.

Children with known allergies to any ingredients or those with severe infections require medical review before commencing treatment. Contact your doctor immediately if you develop allergic reactions (breathing difficulty, chest tightness, rash, itching, hives, or swelling of lips, tongue, or face), infection (acute or chronic), tuberculosis, intestinal ulcers or diverticulitis (small pouches in the digestive tract), liver disease, cancer, kidney function impairment, or persistent headaches. Inform your doctor of any history of macrophage activation syndrome, characterised by activation and uncontrolled proliferation of specific blood cells. Elderly patients face increased infection risk compared to the general population and require careful clinical monitoring during treatment. Medical consultation is necessary if you are planning pregnancy, suspect pregnancy, or are breastfeeding.

Rheumatoid arthritis Giant cell arteritis (GCA) Polyarticular Juvenile Idiopathic Arthritis (pJIA) Systemic Juvenile Idiopathic Arthritis (sJIA) Cytokine release syndrome

Actemra 200mg injection inhibits the function of a particular protein known as interleukin-6, which plays a role in the body's inflammatory responses. By blocking this protein, it can help decrease inflammation within your body.

Actemra 200mg injection will be administered to you by a healthcare professional in a hospital setting. It is usually administered in the vein (intravenous). Your doctor will decide the dose, route of administration, and frequency based on your disease condition and other factors.

Side effects are unwanted symptoms caused by medicines. Even though all medicines cause side effects, not everyone gets them. Serious Allergic reaction (difficulty with breathing, chest tightness, rash, itching, hives, swelling in the lips, tongue, or face) Fever and chills Mouth or skin blisters Stomach ache Common Upper respiratory tract infections (cough, blocked nose, runny nose, sore throat and headache) High blood fat (cholesterol) levels Injection site reactions. Lung infection (pneumonia) Shingles (herpes zoster) Cold sores (oral herpes simplex), blisters Eye infection (conjunctivitis) Headache, dizziness, high blood pressure Mouth ulceration, stomach pain Fluid retention (edema) in the lower legs, weight increase Cough, shortness of breath Low white blood cell counts (neutropenia, leucopenia) Abnormal liver function tests (increased transaminases) Increased bilirubin shown by blood tests Low fibrinogen levels in the blood (a protein involved in blood clotting)

Talk to your doctor if you have recently been vaccinated or are planning a vaccination because a certain vaccination (Live vaccine) should not be given while taking actemra 200mg injection. Your doctor will advise you to check the blood if you have low white blood cells, platelets, or elevated liver enzymes before giving you the medicine.