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Actinocin 0.5mg Injection

Salt Composition: DACTINOMYCIN

₹313.00₹347.50

Inclusive of all taxes

Categories: Oncology

Conditions: Anti Cancer

Product Introduction

Actinocin 0.5mg Injection is an anti-cancer medication containing Dactinomycin, also known as actinomycin D. It belongs to the class of antineoplastic antibiotics used in chemotherapy. This medicine is primarily used to treat specific cancer types by slowing or stopping the growth of cancer cells. Dactinomycin is typically administered as an injection under supervision of a trained healthcare professional. Actinocin 0.5mg Injection is used in various cancer types including Wilms tumour, rhabdomyosarcoma, Ewing's sarcoma, and testicular cancer, among others. Though effective, it must be used cautiously in patients with liver disease or low blood counts. It is not recommended during pregnancy or while breastfeeding unless absolutely necessary. Patients undergoing this treatment require close medical monitoring due to the risk of side effects and drug interactions.

Uses

Actinocin 0.5mg Injection is FDA-approved for the treatment of the following cancers: Wilms' tumour (kidney cancer in children) Rhabdomyosarcoma (soft tissue cancer) Ewing’s sarcoma (bone cancer) Gestational trophoblastic neoplasia (cancer linked to pregnancy) Testicular cancer (when combined with other chemotherapy drugs) Certain types of solid tumours in children

How it works

Dactinomycin works by interfering with the DNA of cancer cells. It binds to their genetic material and prevents them from multiplying. When cancer cells can’t grow or divide, they eventually die. This helps to shrink tumours and slow down the spread of cancer. Since the drug targets rapidly dividing cells, it can also affect some healthy cells, which is why side effects may occur. However, its action makes it highly effective in stopping the progression of certain fast-growing cancers when used as prescribed by a cancer specialist.

How to Use

Actinocin 0.5mg Injection is given as an intravenous (IV) injection under the supervision of a trained oncologist or nurse. The dosage and schedule depend on the type of cancer being treated, the patient’s weight, and overall health. It is not taken orally and should never be self-administered. There are no food restrictions linked directly to this medicine, but patients should follow any dietary advice given by their doctor during treatment.

Side Effects

Common Side Effects Nausea or vomiting Hair loss (temporary) Mouth sores Diarrhea Fatigue Skin peeling or redness at the injection site Serious Side Effects Severe infection due to low white blood cell count Liver damage (yellowing of eyes/skin) Unusual bleeding or bruising Trouble breathing or chest pain Swelling or pain at the injection site

Expert Tips

Actinocin 0.5mg Injection is a powerful chemotherapy drug and should only be taken under close medical supervision. During treatment, it is important to maintain good hygiene and avoid crowded places to reduce infection risk due to a weakened immune system. Patients are advised to follow up regularly for blood tests and liver function monitoring. Report any signs of fever, unusual tiredness, or bleeding to your doctor immediately. Avoid self-medicating or taking any other drug without your oncologist's approval during the course of therapy.

References

  1. https://www.accessdata.fda.gov/drugsatfda_docs/label/2012/050682s029s030lbl.pdf
  2. https://www.sciencedirect.com/topics/pharmacology-toxicology-and-pharmaceutical-science/dactinomycin
  3. https://go.drugbank.com/drugs/DB00970
  4. https://www.cancer.gov/about-cancer/treatment/drugs/dactinomycin

Safety Advice

Pregnancy: unsafe Actinocin 0.5mg Injection is not recommended during pregnancy as it may harm the developing baby. Women of childbearing age should use effective contraception during treatment.

Lungs: Consult your doctor Actinocin 0.5mg Injection may affect lung function in rare cases, especially when combined with radiation therapy. Lung function tests may be advised during treatment.

Breastfeeding: unsafe Actinocin 0.5mg Injection should not be used while breastfeeding as the drug may pass into breast milk and harm the baby. Consult your doctor about safe alternatives.

Disclaimer

The information provided on this page is intended for general informational purposes only and should not be considered as medical advice. Always consult a qualified healthcare professional before starting, stopping, or changing any medication. Self-medication can be harmful. Med For Rare does not endorse self-diagnosis or self-treatment.

Written By: Muskan Patel, M.Pharm

Reviewed By: Dr. Vishwa Patel, MBBS