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Adcetris 50mg Injection
Salt Composition: BRENTUXIMAB VEDOTIN
- Manufacturer: TAKEDA PHARMACEUTICALS INDIA PVT LTD
- Pack Size: 1 VIAL(s)
- Dosage Form: INJECTION
- Strength: 50MG
- Prescription Required
- Cold Chain
- Prepaid Only. Non-Returnable.
- Storage: Store Adcetris 50mg Injectionvedot in in a refrigerator (2 °C - 8 °C). Do not freeze.
₹172032.00₹208789.69
Inclusive of all taxes
Product Introduction
Adcetris 50mg Injection is an anticancer medication containing brentuximab vedotin, a CD30-directed monoclonal antibody–drug conjugate (ADC). It is used to treat classical Hodgkin lymphoma, systemic anaplastic large cell lymphoma (sALCL), and cutaneous T-cell lymphoma (CTCL). It may be administered as first-line treatment or following ineffectiveness of other treatments. Adcetris targets CD30 protein on cancer cells and delivers monomethyl auristatin E directly into them. This targeted mechanism helps destroy cancer cells while reducing damage to healthy tissue. The medicine is administered intravenously by a healthcare provider in a hospital setting. Self-administration is not appropriate. Dosage and treatment duration are determined by your doctor based on your condition, body weight, and response to therapy.
Uses
Treatment of classical Hodgkin lymphoma Treatment of systemic anaplastic large cell lymphoma (sALCL) Treatment of cutaneous T-cell lymphoma (CTCL)
How it works
Adcetris 50mg Injection consists of a monoclonal antibody that binds to CD30, a protein found on some cancer cells. Once attached, it delivers a cell-killing agent (MMAE) directly into the cancer cell, leading to its destruction. This reduces damage to nearby healthy cells and enhances treatment effectiveness.
Side Effects
Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them. Common Side Effects: Peripheral neuropathy (tingling, numbness) Fatigue Nausea Diarrhea Constipation Vomiting Fever Decreased white blood cell count Hair loss Weight loss Abdominal pain Anemia Upper respiratory tract infections Mouth ulcers (stomatitis) Muscle pain Itching Serious Side Effects: Infusion-related reactions (fever, rash, shortness of breath, chills) Allergic reactions Inflammation of the pancreas Memory loss or confusion Blurred vision or difficulty walking Unusual bleeding or bruising Liver problems (yellowing of skin or eyes, dark urine)
Expert Tips
Adcetris is a targeted therapy—report numbness, tingling, or muscle weakness immediately. Contact your doctor if you develop a fever over 100.5°F, cough, chills, or difficulty urinating. Infusion reactions can occur within 24 hours—seek help for breathing difficulty or rash. Report signs of liver injury like yellow skin, fatigue, or dark urine. Regular blood monitoring is essential to detect low blood counts or liver function abnormalities.
References
- Takeda Pharma A/S, Electronic Medicines Compendium (EMC), [Revised on June 2022] [Accessed on 11 August 2023], https://www.medicines.org.uk/emc/files/pil.2859.pdf
- Brentuximab vedotin. Macmillan Cancer Support, [Revised on 1 July 2022], [Accessed on 11 August 2023], www.macmillan.org.uk/cancer-information-and-support/treatments-and-drugs/brentuximab
- Adcetris, INN- brentuximab vedotin. [Revised on 10 Jan 2023], [Accessed on 11 August 2023], www.ema.europa.eu/en/documents/product-information/www.ema.europa.eu/en/documents/product-information/adcetris-epar-product-information_en.pdf
- Seattle Genetics, Inc. US Food & Drug Administration. [Revised Nov 2014], [Accessed on 11 August 2023], https://www.accessdata.fda.gov/drugsatfda_docs/label/2014/125388_s056s078lbl.pdf
Safety Advice
Pregnancy: unsafe Adcetris 50mg injection can cause fetal harm to the fetus when administered to pregnant women. Consult your doctor if you are pregnant or planning for pregnancy during the treatment.
Lungs: Consult your doctor It is unknown whether Adcetris 50mg injection is safe for patients with lung problems. Inform your physician if you have lung disease before starting the treatment.
Breastfeeding: Consult your doctor If breastfeeding, consult your doctor before starting the treatment with Adcetris 50mg injection.
Disclaimer
The information provided on this page is intended for general informational purposes only and should not be considered as medical advice. Always consult a qualified healthcare professional before starting, stopping, or changing any medication. Self-medication can be harmful. Med For Rare does not endorse self-diagnosis or self-treatment.