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Adfrar 20mg Injection

Salt Composition: ADALIMUMAB

₹5922.00₹23437.50

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Adfrar 20mg Injection

Categories: Rheumatology

Conditions: Osteoporosis

Product Introduction

Adfrar 20mg Injection contains the active ingredient adalimumab. It is an antirheumatic agent that belongs to the class of medications called TNF (tumour necrosis factor) inhibitors. It is used alone or with other medications to relieve the symptoms of certain autoimmune disorders. It is used to treat rheumatoid arthritis (a condition in which the body attacks its joints, causing pain, swelling, and loss of function), polyarticular juvenile idiopathic arthritis (a condition that affects children in which the body attacks its own joints, causing pain, swelling, loss of function, and delays in growth and development). It is also indicated to treat enthesitis-related arthritis, ankylosing spondylitis (a condition in which the body attacks the joints of the spine and other areas, causing pain and joint damage), axial spondyloarthritis without radiographic evidence of ankylosing spondylitis, psoriatic arthritis (a condition that causes joint pain and swelling and scales on the skin), plaque psoriasis, hidradenitis suppurativa (a skin disease that causes pimple-like bumps in the armpits, groin, and anal area), Crohn's disease, ulcerative colitis (a condition which causes swelling and sores in the lining of the colon and rectum), and non-infectious uveitis (swelling and inflammation of different areas of the eye). Do not use Adfrar 20mg Injection if you are allergic to adalimumab or any of the other ingredients present in this medicine. Do not take this medicine if you have active tuberculosis or other severe infections. Do not take consume this medicine if you have moderate or severe heart failure. Consult your physician if you have any active infection before starting the treatment. Tell your doctor if you have lung problems, heart diseases, liver or kidney disorders before initiating the treatment. If you are pregnant, or are planning to have a baby, ask your doctor for advice about taking this medicine.

Uses

Rheumatoid arthritis Polyarticular juvenile idiopathic arthritis Enthesitis-related arthritis Ankylosing spondylitis Axial spondyloarthritis without radiographic evidence of ankylosing spondylitis Psoriatic arthritis Plaque psoriasis Hidradenitis suppurativa Crohn’s disease Ulcerative colitis Non-infectious uveitis

How it works

The active ingredient in this medicine is a human monoclonal antibody. Monoclonal antibodies are proteins that attach to a specific target. The target of Adfrar 20mg Injection is a protein called tumour necrosis factor (TNFα), which is involved in the immune (defence) system and at increased levels in inflammatory diseases. By attaching to TNFα, Humira decreases inflammation in these diseases.

How to Use

Your doctor will decide the dose, duration, and frequency of administration based on your disease condition, severity and other factors. Always use this medicine exactly as your doctor or pharmacist has told you. Check with your doctor or pharmacist if you are not sure. This medicine is to be administered by injection under the skin (subcutaneously). Your doctor or other healthcare professional will train you on how to use this injection. Do not self-administer this injection until you get trained. Your doctor will decide the dose, duration, and frequency of administration based on your disease condition, severeity and other factors.

Side Effects

Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them. Common Injection site reactions Rash Headache Sinusitis Upper respiratory infections Fever Serious Heart problems Abnormal heart beat Severe skin reactions GI bleeding Abnormal blood count values Liver injury Bone problems Infections Severe respiratory problems

Expert Tips

Certain vaccines may cause infections and should not be given while receiving this medicine; check with your doctor before you receive any vaccines. Inform your doctor if you have or have had a hepatitis B infection because this medicine may increase your chance of getting the infection again. You may be taught how to give your medicine at home. Make sure you understand all instructions before giving yourself an injection. You will be shown the body areas where this shot can be given. Use a different body area each time you give yourself a shot. Keep track of where you give each shot to make sure you rotate body areas. Do not inject into skin areas that are red, bruised, tender, or hard. Take a dose as soon as you remember. If it is almost time for your next dose, wait until then and take a regular dose. Do not take extra medicine to make up for a missed dose.

References

  1. Goodman & Gilman’s, The Pharmacological Basis of Therapeutics, Immunosuppressants, tolerogens, and immunostimulants, 12th edition, 2011, 1018.
  2. KD Tripathi, Essentials of Medical Pharmacology, Antirheumatoid and antigout drugs, 7th edition, 2013, 213.
  3. AbbVie Ltd, Electronic medicines compendium (emc), [ Revised on April 2021] [ Accessed on July 2023], https://www.medicines.org.uk/emc/files/pil.2150.pdf
  4. AbbVie Inc, US Food and Drug Administration, [ Revised on Feb 2021] [ Accessed on July 2023], https://www.rxabbvie.com/pdf/humira.pdf

Safety Advice

Pregnancy: Consult your doctor Do not take Adfrar 20mg Injection during pregnancy unless your doctor says. Inform your physician if you are pregnant, suspecting, or planning to get pregnant during the treatment. Use effective contraception during the treatment and for at least 5 months after the last dose.

Lungs: Consult your doctor Adfrar 20mg Injection should be taken cautiously in patients with lung problems. Inform your physician if you have any lung diseases before initiating the treatment.

Breastfeeding: safe Adfrar 20mg Injection can be used during breastfeeding. However, inform your physician if you are breastfeeding.

Disclaimer

The information provided on this page is intended for general informational purposes only and should not be considered as medical advice. Always consult a qualified healthcare professional before starting, stopping, or changing any medication. Self-medication can be harmful. Med For Rare does not endorse self-diagnosis or self-treatment.

Written By: Muskan Patel, M.Pharm

Reviewed By: Dr. Vishwa Patel, MBBS