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Adlante 10mg Capsule

Salt Composition: LENVATINIB

₹2393.00₹2990.63

Inclusive of all taxes

Categories: Oncology

Conditions: Anti Cancer

Product Introduction

Adlante 10mg Capsule contains the active ingredient Lenvatinib, a tyrosine kinase inhibitor. It is indicated for progressive or advanced thyroid cancer when radioactive iodine therapy has not been beneficial. The medicine is also prescribed for patients with previously untreated liver cancer who are not eligible for surgical treatment.

Anaplastic thyroid carcinoma, an advanced form of thyroid cancer, typically occurs in patients over 60 years of age. It is characterised by an enlarged and firm thyroid gland and hoarseness in the voice due to paralysis of the recurrent laryngeal nerve. Hepatocellular carcinoma develops in the context of preexisting liver disease such as cirrhosis or chronic hepatitis B infection. In these cases, doctors may prescribe Adlante capsules after considering the patient's clinical condition and determining the suitability of the 10mg dose.

Patients who have experienced an allergic reaction to Adlante 10mg Capsule or any of its components should not use this medication. It is important to inform your dentist or oral surgeon if you are using this drug, as it can impair wound healing and increase the risk of bleeding.

The availability of alternative formulations and the pricing of Adlante 10mg in India may influence treatment decisions. Information on effectiveness, safety profile, and reported side effects can assist patients in understanding this medication option.

Uses

Adlante uses in the treat the following conditions: Certain types of advanced thyroid cancer Advanced Liver cancer Certain types of kidney cancer Endometrial cancer

How it works

Lenvatinib in Adlante 10mg Capsule blocks the enzyme receptor tyrosine kinases (RTKs). RTKs develop new blood vessels that supply oxygen and nutrients to the cells and help them grow. This medicine inhibits the receptors that facilitate the growth of blood vessels in tumor cells. RTKs are present in high concentrations in cancer cells, and administration of this medicine slows down the rate of cancer cells’ growth and multiplication.

How to Use

Adlante 10mg Capsule is an oral medication that is usually taken once a day, at approximately the same time each day, with or without food. It should be taken as prescribed by a doctor or other healthcare provider. These capsules should be swallowed whole with a glass of water. They should not be crushed, chewed, or opened, as this can affect the way the medication is absorbed and decrease its effectiveness. You should not take a double dose to make up for the second dose.

Side Effects

Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them. Adlante 10mg side effects are Serious: Feeling numb or weak on 1 side of the body Severe headache Fever Confusion Difficulty speaking Vision changes Dizziness Chest pain or pressure Pain in arms, jaw, neck, and back Breathing problems Severe stomach pain Blood clot formation Blood in stools or coughing blood Liver problems Pain or soreness in the mouth, teeth, or jaw Common: High or low BP Loss of appetite Nausea, vomiting, constipation, diarrhea, or indigestion Tiredness Hoarse voice Leg swelling Rashes Pain in joints or muscles Hair loss Sleeplessness Protein in urine, frequent urination Low potassium, magnesium, and calcium levels in the blood Dehydration Skin problems Gall bladder inflammation Increase in the values of cholesterol, thyroid-stimulating hormone, digestive enzymes Delayed wound healing

References

  1. Eisai Europe Limited, Electronic Medicines Compendium (EMC), [Revised on Mar 2021] [Accessed on 20th April 2023], https://www.medicines.org.uk/emc/files/pil.68100.pdf
  2. Suyama and Iwase, Lenvatinib: A promising molecular targeted agent for multiple cancers, Cancer Control, 2018, 25, 1-5, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6056795/pdf/10/1177 10732710818789361.pdf
  3. Q.M. Anstee, D.E.J. Jones, Liver and Biliary Tract Disease, Davidson’s Principles and Practice of Medicine, 22nd Edition, 20110, 921-988.
  4. M.W.J. Strachan, J. Newell-Price, Endocrine disease, Davidson’s Principles & Practice of Medicine, 22nd Edition, 20110, 733-796.
  5. Eisai Inc U.S Food and Safety Drug Administration (FDA) [Last revised Aug 2018], [Accessed on 20th April 2023], https://www.accessdata.fda.gov/drugsatfda_docs/label/2018/2069107s007lbl.pdf

Safety Advice

Pregnancy: unsafe Adlante 10mg Capsule is unsafe during pregnancy as it can cause fetal harm. It is recommended to avoid this medication during pregnancy.

Lungs: unsafe Adlante 10mg Capsule can cause side effects that affect the lungs, such as cough, shortness of breath, and difficulty breathing. If a person experiences any of these symptoms while taking it, they should notify their healthcare provider right away.

Breastfeeding: unsafe Breastfeeding is not recommended while taking Adlante 10mg Capsule, as it can potentially harm the nursing infant.

Disclaimer

The information provided on this page is intended for general informational purposes only and should not be considered as medical advice. Always consult a qualified healthcare professional before starting, stopping, or changing any medication. Self-medication can be harmful. Med For Rare does not endorse self-diagnosis or self-treatment.

Written By: Muskan Patel, M.Pharm

Reviewed By: Dr. Vishwa Patel, MBBS