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Adplatin 50mg Injection

Salt Composition: OXALIPLATIN

₹3933.00₹4916.25

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Adplatin 50mg Injection

Categories: Oncology

Conditions: Anti Cancer

Product Introduction

Adplatin 50mg Injection is a platinum-based antineoplastic agent containing the active ingredient Oxaliplatin. It is prescribed for stage 3 colon cancer following surgical resection of the primary tumour, and for metastatic colon and rectal cancer. The medicine is used in combination with other anti-cancer agents. Colorectal cancer typically develops in the rectum and large intestine, arising from accumulation of various genetic mutations. Both environmental and genetic factors contribute to colorectal cancer development. This medicine is effective against tumours resistant to cisplatin therapy. Inform your doctor if you are allergic to Adplatin 50mg Injection or any of its ingredients. Before beginning treatment, inform your physician if you have mild or moderate kidney problems, liver problems, or heart disorders. Disclose all medicines you are taking, including vaccinations. This medicine is not recommended for pregnant or breastfeeding women.

Uses

Treatment of colon and rectal cancer.

How it works

Adplatin 50mg Injection works by damaging the genetic material, such as DNA and RNA of the cancer cells, that interferes with the growth of cancer cells. It stops their growth and multiplication of cancer cells.

How to Use

Adplatin 50mg Injection is given by slow injection into one of your veins (an intravenous infusion) over 2 to 6 hours. Your physician will prescribe a dose according to your body surface area.

Side Effects

Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them. Serious Abnormal bleeding or bruising Severe allergic reactions Continuous diarrhea and vomiting Sore throat and fever Irregular heartbeat Muscle pain and weakness Mouth ulcers Extreme tiredness and breathlessness Headache Altered mental function Blurred vision Seizures Common A reduced number of blood cells Unpleasant sensation in the throat Diarrhea Nausea, vomiting High risk of infections Indigestion and heartburn Blood in urine Blood clots High BP Depression and insomnia Low levels of calcium in the blood

Expert Tips

It is suggested that women should use effective birth control for at least four weeks before starting and during treatment with Adplatin 50mg Injection. Male patients are advised to use effective contraception during therapy and six months after treatment to avoid fathering children. Before receiving Adplatin 50mg Injection treatment, male patients should get advice on sperm conservation. Pregnant women should not use or handle this drug since it contains cytotoxic substances. This medication is handled exclusively by healthcare professionals who use sterile single-use gloves, protective masks, hats, and goggles. Vaccinations should be avoided when using this drug since they may cause serious side effects.

References

  1. 1. Hospira UK Limited, Electronic Medicines Compendium (EMC), [Revised on Dec 2020] [Accessed on 25th Jun 2021], https://www.medicines.org.uk/emc/files/pil.6286.pdf 2. Edward Chu, Cancer Chemotherapy, Lange’s Basic and Clinical Pharmacology, 14th Edition, 2018, 948-976. 3. KD Tripathi, Anticancer Drugs, Essentials of Medical Pharmacology, 8th Edition, 2019, 915-936.

Safety Advice

Pregnancy: unsafe Adplatin 50mg Injection is unsafe to use during pregnancy; hence it is not recommended. Women should use effective contraception during and after the 4 months of treatment.

Lungs: Consult your doctor Inform your physician before starting treatment with Adplatin 50mg Injection if you have lung disease or abnormal liver function. Your physician will prescribe the dose accordingly.

Breastfeeding: unsafe It is unsafe to breastfeed during treatment with Adplatin 50mg Injection. Your physician might suggest you stop breastfeeding for some time, depending on your condition.

Disclaimer

The information provided on this page is intended for general informational purposes only and should not be considered as medical advice. Always consult a qualified healthcare professional before starting, stopping, or changing any medication. Self-medication can be harmful. Med For Rare does not endorse self-diagnosis or self-treatment.

Written By: Muskan Patel, M.Pharm

Reviewed By: Dr. Vishwa Patel, MBBS