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Adthal 100mg Capsule

Salt Composition: THALIDOMIDE

₹500.00₹624.38

Inclusive of all taxes

Categories: Oncology

Conditions: Anti Cancer

Product Introduction

Adthal 100mg Capsule belongs to the class of immunomodulatory agents. The active ingredient is thalidomide 100mg. It is indicated for treating patients recently diagnosed with multiple myeloma, a type of cancer affecting plasma cells in the bone marrow that grow uncontrolled and accumulate, damaging bones and kidneys. It is also prescribed for moderate to severe erythema nodosum leprosum (ENL) lesions in leprosy, a chronic disease caused by Mycobacterium leprae that affects the skin and nerves.

Common side effects include sleepiness, headache, dizziness, rashes, pain, tiredness, constipation, nausea, impotence, loss of appetite, fever, and depression. Inform your doctor if any of these side effects persist or are concerning.

Use an effective contraceptive method to avoid pregnancy during treatment. Inform your doctor if you are allergic to this medication or its ingredients. Disclose if you have a history of blood clots, heart attack, neuropathy (nerve damage causing pain in hands or feet), slow heart rate, low or high blood pressure, liver or kidney problems, or viral infections including HIV, hepatitis B virus, or varicella zoster. Your doctor will monitor thyroid function before and during treatment.

Discontinue this medication immediately and consult your doctor if you think you are pregnant, have irregular periods, missed a period, experience any change in menstrual bleeding, or have had unprotected sexual intercourse. This medication is not recommended for adolescents and children under 18 years of age.

Uses

Adjunct to Dexamethasone for treating newly diagnosed multiple myeloma. Treatment of moderate to severe leprosy. Prevention of recurrence of skin lesions in leprosy.

How it works

Adthal 100mg Capsule reduces inflammation and regulates the immune system. It works by enabling the body’s immune system and attacking the cancer cells. It inhibits tumor necrosis factor-alpha, increases the production of interleukin-10 and interacts with the T-cells to generate an immune response. It halts the growth of blood vessels in cancer cells and arrests their development.

How to Use

Take the Adthal 100mg Capsule as your physician advises. Take medicine at a fixed time. Do not crush, chew, or open the medicine. Your physician will decide the correct dosage and duration based on age, body weight, and disease condition.

Side Effects

Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them. Serious Nerve damage Decreased blood pressure Low WBC count Slow heartbeat Serious allergic reactions Tumor lysis syndrome Sudden pain in the chest or difficulty breathing Pain and swelling of legs Bleeding or bruising without injury Common Sleepiness Rashes Headache Dizziness Impotence Decreased energy or strength Pain Tiredness Low calcium and blood count levels Swelling of hands and feet Constipation Numbness or tingling Nausea and reduced appetite Anxiety, depression, confusion and mood swings Fever Weight loss or weight gain Indigestion, vomiting and dry mouth Muscle cramps Blurred vision Chest infection, lung disease Ear problems Kidney damage

Expert Tips

Talk to your physician if you have had a heart attack, blood disorders, high BP or high cholesterol. Inform your physician before starting treatment, seizures, skin reactions or severe infections. Inform your physician if you smoke or drink alcohol. Before starting the treatment, inform your doctor about all the underlying medical conditions. Do not stop the medicine until your doctor advises. Do not double-dose the medicine to make up for a forgotten dose. Notify your doctor if you experience any serious side effects. Contact your doctor for more information.

References

  1. 1. Celgene Europe B.V, Electronic Medicines Compendium (EMC), [Revised on Aug 2021] [Accessed on 19th August 2023], https://www.medicines.org.uk/emc/files/pil.6317.pd 2. Celgene Corporation, US Food and Drug Administration, [Revised on Jun 2019] [Accessed on 19th August 2023], https://www.accessdata.fda.gov/drugsatfda_docs/label/2019/020785s067lbl.pdf 3. Douglas F. Lake and Adrienne D. Briggs, Immunopharmacology, Lange’s Basic & Clinical Pharmacology, 14th Edition, 2018, 977-1002. 4. D.H. Dockrell, S. Sundar, B.J. Angus, R.P. Hobson, Infectious Disease, Davidson’s Principles and Practice of Medicine, 22nd Edition, 2014, 293-386.

Safety Advice

Pregnancy: unsafe Adthal 100mg Capsule causes birth defects and the death of the fetus and it is unsafe to consume during pregnancy. Inform your physician before taking this medicine if you are pregnant or think you might be pregnant.

Lungs: Consult your doctor It is unknown whether Adthal 100mg Capsule is safe for patients with lung problems. Inform your physician if you have any lung disease before starting the treatment. Contact your doctor if you experience any lung-related symptoms.

Breastfeeding: unsafe Adthal 100mg Capsule is unsafe to consume because it passes through breast milk. Consult your physician for advice before breastfeeding.

Disclaimer

The information provided on this page is intended for general informational purposes only and should not be considered as medical advice. Always consult a qualified healthcare professional before starting, stopping, or changing any medication. Self-medication can be harmful. Med For Rare does not endorse self-diagnosis or self-treatment.

Written By: Muskan Patel, M.Pharm

Reviewed By: Dr. Vishwa Patel, MBBS