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Adtrinib 200mg Tablet 30's
Salt Composition: SORAFENIB
- Manufacturer: ADLEY FORMULATIONS
- Pack Size: 30 TABLET(s) IN A BOTTLE
- Dosage Form: TABLET
- Strength: 200MG
- Prescription Required
- Storage: Store Adtrinib Tablet Tablet in the original package at room temperature (20°C to 25°C). Keep it out of reach from children.
₹2068.00₹2585.00
Inclusive of all taxes
Product Introduction
Adtrinib Tablet is a multikinase inhibitor containing sorafenib, used to treat advanced renal cell carcinoma, hepatocellular carcinoma, and thyroid cancer. The medicine is not recommended if you are allergic to sorafenib or other ingredients in the formulation. Contact your doctor immediately if you develop skin rashes, heart problems, chest pain, bleeding problems, high blood pressure, or if you have had or are about to undergo surgery. Use in children and adolescents is not recommended. Patients with diabetes require frequent blood sugar monitoring to determine whether anti-diabetic medication dosage adjustments are necessary to reduce the risk of hypoglycaemia. Your doctor will monitor liver function tests and fluid and electrolyte balance to identify and manage potential side effects promptly.
Uses
Advanced renal cell carcinoma Advanced hepatocellular carcinoma Differentiated thyroid carcinoma
How it works
Adtrinib Tablet works by inhibiting multiple protein kinases involved in tumour cell proliferation and angiogenesis (the formation of new blood vessels that supply tumours). Specifically, it targets receptors for vascular endothelial growth factor (VEGF), platelet-derived growth factor (PDGF), and Raf kinases, which play key roles in cancer development and progression. This stops the growth and spread of the tumour cells to other organs, as well as the formation of blood vessels in the tumour cells.
How to Use
A healthcare professional in a hospital setting will prescribe the medicine to you. It is not recommended to take this medication with meals that are high in fat since this may reduce Adtrinib Tablet's effectiveness. If you plan to eat one, take the pills at least one hour before or two hours after. Your healthcare professional will decide the dose based on your conditions. Avoid crushing, opening, or dissolving the tablet; swallow it whole with a glass of water. Take the Adtrinib tablet at the same time every day.
Side Effects
Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them. Common: Nausea Vomiting Fatigue Diarrhoea Alopecia Hand foot skin reaction Gut wall bleeding Serious: gastrointestinal perforation abnormal heart rhythm (QT prolongation) inflammation of the liver breathing or swallowing difficulties Stevens Johnsons Syndrome and toxic epidermal necrolysis Decreased blood flow to the heart Increased risk of bleeding (blood in urine, stool, vomit, cough, etc)
Expert Tips
Follow all instructions and dosing recommendations provided by your healthcare provider. Do not take more or less of the medication than prescribed. Report any new or worsening symptoms to your healthcare provider immediately, especially if they relate to your lungs, eyes, skin, liver, kidneys, heart, or bleeding. When undergoing this therapy, stay out of direct sunlight and wear sunscreen with an SPF of at least 50 before going outside. Adtrinib Tablet should not be stopped without first talking to your doctor. Even if you feel better or see a change in your symptoms, you should still talk to your doctor before stopping Adtrinib Tablet. It is recommended to inform your doctor about other anticancer drugs you have been taking. It's critical to maintain a sufficient fluid intake because dehydration can exacerbate symptoms such as diarrhea and other gastrointestinal disorders. Remember to attend all scheduled appointments and follow-up visits with your healthcare provider to ensure your treatment is effective and any side effects are managed appropriately.
References
- 1. Bayer (Pty) Ltd, [Revised on 22nd Apr 2016] [Accessed on 15th March 2024], https://www.bayer.com/sites/default/files/NEXAVAR_200_EN_PI.pdf 2. Bayer HealthCare Pharmaceuticals Inc., US Food & Drug Administration, [Revised on Dec 2018] [Accessed on 15th March 2024]], https://www.accessdata.fda.gov/drugsatfda_docs/label/2018/021923s020lbl.pdf 3. Bayer AG, European Medicines Compendium (emc), [Revised on April 2023], [Accessed on 15th March 2024], https://www.medicines.org.uk/emc/files/pil.226.pdf 4. Zentiva Pharma UK Limited, Medicines Compendium (emc), [Revised on April 2022], [Accessed on 15th March 2024] https://www.medicines.org.uk/emc/files/pil.13098.pdf 5. KD Tripathi, Anticancer Drugs, Essentials of Medical Pharmacology, 8th Edition, 2019, 915-936.
Safety Advice
Pregnancy: unsafe It is not recommended to take Adtrinib Tablet during pregnancy as it may harm your unborn baby. It is necessary to inform your doctor if you are pregnant or planning to become pregnant
Lungs: Consult your doctor Consult your doctor if you have any lung diseases before starting the treatment with Adtrinib Tablet.
Breastfeeding: unsafe It is unknown whether Adtrinib Tablet passes into the breast milk. It is not recommended to nurse a child during the therapy. This medication might affect your baby's growth and development. Please consult your doctor before breastfeeding.
Disclaimer
The information provided on this page is intended for general informational purposes only and should not be considered as medical advice. Always consult a qualified healthcare professional before starting, stopping, or changing any medication. Self-medication can be harmful. Med For Rare does not endorse self-diagnosis or self-treatment.