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Advin 50mg Injection

Salt Composition: VINORELBINE

₹13902.00₹17376.56

Inclusive of all taxes

Categories: Oncology

Conditions: Anti Cancer

Product Introduction

Advin 50mg Injection is a chemotherapy medication containing the active ingredient Vinorelbine. It is classified as a vinca alkaloid and is indicated for the treatment of non-small cell lung cancer and breast cancer. Cancer is a disease characterised by uncontrolled and abnormal cell multiplication. This medication is not recommended for children and adolescents under 18 years of age. Common side effects associated with Advin 50mg Injection include nausea, vomiting, low blood cell counts, fatigue, weakness, hair loss, pain in the jaws, joints and muscles, diarrhoea, swelling or sores in the throat or mouth, and injection site reactions such as redness, burning pain, and vein discolouration. Inform your physician if these side effects are bothersome or persistent. Report to your doctor if you have an allergy to Advin 50mg Injection and its components. During treatment with Advin 50mg Injection, inform your physician if you develop signs or symptoms of infection (cough, fever, chills, or joint pain), severe chest pain, a history of myocardial infarction, or liver disease. Your physician will monitor blood cell counts before and during treatment with this medication. Use effective contraception during treatment and for at least three months after the final dose. Inform your physician of all medications you are taking, including herbal medicines and nutritional supplements. Live attenuated vaccines are not recommended during this treatment. Consult your healthcare professional if you have received any vaccines recently or require vaccination.

Uses

Non-small cell lung cancer (NSCLC) Breast cancer

How it works

Advin 50mg Injection works by inhibiting the microtubule structures within the cell. Microtubule structures help cancer cells to divide and multiply. Inhibition of these structures slows the growth and multiplication of cancer cells

How to Use

This medication is administered into a vein by your healthcare provider. The dose and duration is decided by your physician depending on the condition.

Side Effects

Side effects are unwanted symptoms caused by medicines. Even though all medicines cause side effects, not everyone gets them. Serious: Severe allergic reactions (rash, difficulty in breathing, swelling of eyelids, lips, face, or throat) Severe chest pain Severe low blood pressure (severe dizziness, lightheadedness when you stand up) Severe constipation with abdominal pain Major infection (cough, fever, chills) Common: Nausea, vomiting Low blood cell counts, weakness Hair loss Swelling or sores in the throat or mouth Injection site reactions (redness, burning pain, vein discoloration) Pain in the jaws, joints, and muscles Tiredness Diarrhea

Expert Tips

It is suggested that women should use effective birth control for at least three months before starting and during treatment with Advin 50mg Injection. Male patients are advised to use effective contraception during therapy and three months after treatment to avoid fathering children. Before receiving Advin 50mg Injection treatment, male patients should get advice on sperm conservation. Your doctor may take regular blood tests to monitor your blood cell count, platelet count, and liver function.

References

  1. Pierre Fabre Limited, Electronic medicines compendium (EMC), [Revised on Nov 2022] [ Accessed on 1st Dec 2022], https://www.medicines.org.uk/emc/files/pil.3912.pdf
  2. Goodman & Gilman’s, The Pharmacological Basis of Therapeutics, Cytotoxic agents, 12th edition, 2011, 1706.
  3. KD Tripathi, Essentials of Medical Pharmacology, Anticancer drugs, 7th edition, 2013, 865.
  4. Pierre Fabre Medicament, US Food and Drug administration, [Revised on Jan 2022] [ Accessed on 1st Dec 2022], https://www.accessdata.fda.gov/drugsatfda_docs/label/2020/020388s037lbl.pdf
  5. Anna Capasso; Vinorelbine in Cancer therapy; Cancer Drug Targets; Published on July 2012; Accessed on 01/12/2022; https://pubmed.ncbi.nlm.nih.gov/22594474/
  6. Ying-Chun Xu et al; A systematic review of vinorelbine for the treatment of breast cancer; The Breast Journal; Published on April 2013; Accessed on 01/12/2022; https://pubmed.ncbi.nlm.nih.gov/23320984/

Safety Advice

Pregnancy: unsafe Advin 50mg Injection is unsafe to use during pregnancy as it may harm the unborn baby.

Lungs: Consult your doctor It is unknown whether Advin 50mg Injection can be administered to lung failure patients. Please consult your physician if you have any lung problems.

Breastfeeding: unsafe It is not recommended for breastfeeding while taking Advin 50mg Injection.

Disclaimer

The information provided on this page is intended for general informational purposes only and should not be considered as medical advice. Always consult a qualified healthcare professional before starting, stopping, or changing any medication. Self-medication can be harmful. Med For Rare does not endorse self-diagnosis or self-treatment.

Written By: Muskan Patel, M.Pharm

Reviewed By: Dr. Vishwa Patel, MBBS