Afamac 40mg Tablet

Afamac 40mg Tablet is an anticancer medicine containing Afatinib dimaleate as its active ingredient. It is indicated for treatment of patients with non-small cell lung cancer (NSCLC) whose tumours have specific non-resistant abnormal epidermal growth factor receptor (EGFR) gene mutations and patients with metastatic squamous NSCLC that has progressed following platinum-based chemotherapy.

Do not use this medication if you are allergic to Afatinib dimaleate or any of its components. It is not recommended for female patients with body weight below 50 kilograms. Use during pregnancy and breastfeeding is not recommended.

Inform your doctor if you have a history of eye disorders or use contact lenses. Minimise sun exposure, as this medicine may increase skin photosensitivity. It is not suitable for children and adolescents under 18 years of age.

Disclose to your doctor prior to starting treatment if you have kidney disorders, respiratory problems, liver disorders, cardiac conditions, or sugar intolerance. Inform your physician or pharmacist of all current medications, recently used medications, or medications you intend to use, including over-the-counter medicines and herbal preparations.

Do not discontinue this medication without medical consultation.

Non-small cell lung cancer (NSCLC) with epidermal growth factor receptor mutations Metastatic non-small cell lung cancer progressing after platinum-based chemotherapy

It functions by inhibiting the ErbB family of proteins, which includes EGFR (also known as the epidermal growth factor receptor, or ErbB1, ErbB2, ErbB3, and ErbB4) and HER2. Changes in the genes that create these proteins can impact how cancer cells multiply and disseminate. By inhibiting these proteins and their activities, this medication can prevent the growth and proliferation of cancer cells and can help to slow or stop the progression of cancer.

Afamac 40mg Tablet is an oral medication that is usually taken once a day, at approximately the same time each day, before food. If you have already eaten, wait at least 3 hours before taking this medicine. It should be taken as prescribed by a doctor. These tablets should be swallowed whole with a glass of water. They should not be crushed, chewed, or opened, as this can affect how the medication is absorbed and decrease its effectiveness. Take the missed dose as soon as you recall if your next planned dose is more than eight hours away. You should not take a double dose to make up for the second dose.

Like all medications, Afamac 40mg Tablet can cause side effects, although not everyone who takes it will experience them. Serious: Interstitial lung disease (ILD) Severe diarrhoea or dehydration Liver problems Eye problems, such as corneal erosion or ulceration Hemorrhage or bleeding problems Renal impairment Cardiac problems Common: Diarrhea Mouth sores Acne or skin rash Nausea and vomiting Fatigue Loss of appetite Abdominal pain Nail changes, such as nail bed infections or inflammation Dry skin or itching Eye irritation or dryness Respiratory infections

Follow all instructions and dosing recommendations provided by your healthcare provider. Do not take more or less of the medication than prescribed. Report any new or worsening symptoms to your healthcare provider immediately, especially if they relate to your lungs, eyes, skin, liver, kidneys, heart, or bleeding. Women should avoid pregnancy or breastfeeding. Men and women of reproductive age should use effective birth control during the treatment and for at least two weeks after their last dose. Patients should report any signs or symptoms of dehydration, such as dry mouth or decreased urination, to a healthcare provider immediately. Drink plenty of fluids while taking Afamac 40mg Tablet to stay hydrated, especially if you experience diarrhoea as a side effect. When taking Afamac 40mg Tablet, stay away from grapefruit and grapefruit juice as they may interact with the medication and raise the risk of side effects.