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Afasted 30mg Tablet

Salt Composition: AFATINIB DIMALEATE

₹2784.00₹7734.00

Inclusive of all taxes

Categories: Oncology

Conditions: Anti Cancer

Product Introduction

Afasted 30mg Tablet is an anticancer medicine containing Afatinib dimaleate as an active ingredient. It is used to treat patients with non-small cell lung cancer (NSCLC) whose tumours have certain non-resistant abnormal epidermal growth factor receptor (EGFR) genes and patients with metastatic squamous NSCLC progressing after platinum-based chemotherapy. Do not use this medication if you are allergic to Afatinib dimaleate or any of its components. It is not recommended for female patients weighing below 50 kilograms. It is not recommended during pregnancy and breastfeeding. Inform your doctor if you have a history of eye problems or wear contact lenses. Limit sun exposure as this medicine may increase skin sensitivity to sunlight. It is not recommended for children and adolescents under 18 years of age. Do not stop taking this medicine without consulting your doctor. Inform your doctor if you have kidney disorders, breathing problems, liver disorders, heart problems, or intolerance to sugars before taking this medicine. Inform your doctor or pharmacist of all medications you are taking, have recently taken, or may take, including over-the-counter medications and herbal remedies.

Uses

Non-small cell lung cancer (NSCLC) with epidermal growth factor receptor mutations Metastatic non small cell lung cancer progressing after platinum based chemotherapy

How it works

It functions by inhibiting the ErbB family of proteins, which includes EGFR (also known as the epidermal growth factor receptor, or ErbB1, ErbB2, ErbB3, and ErbB4) and HER2. Changes in the genes that create these proteins can have an impact on how cancer cells multiply and disseminate. Through the inhibition of these proteins and its activities, this medication can prevent the growth and proliferation of cancer cells and can help to slow or stop the progression of cancer.

How to Use

Afasted 30mg Tablet is an oral medication that is usually taken once a day, at approximately the same time each day, before food. If you have already eaten, wait at least 3 hours before taking this medicine. It should be taken as prescribed by a doctor. These tablets should be swallowed whole with a glass of water. They should not be crushed, chewed, or opened, as this can affect how the medication is absorbed and decrease its effectiveness. Take the missed dose as soon as you recall if your next planned dose is more than eight hours away. You should not take a double dose to make up for the second dose.

Side Effects

Like all medications, Afasted 30mg Tablet can cause side effects, although not everyone who takes it will experience them. Serious: Interstitial lung disease (ILD) Severe diarrhea or dehydration Liver problems Eye problems, such as corneal erosion or ulceration Hemorrhage or bleeding problems Renal impairment Cardiac problems Common: Diarrhea Mouth sores Acne or skin rash Nausea and vomiting Fatigue Loss of appetite Abdominal pain Nail changes, such as nail bed infections or inflammation Dry skin or itching Eye irritation or dryness Respiratory infections

Expert Tips

Follow all instructions and dosing recommendations provided by your healthcare provider. Do not take more or less of the medication than prescribed. Report any new or worsening symptoms to your healthcare provider immediately, especially if they relate to your lungs, eyes, skin, liver, kidneys, heart, or bleeding. Women should avoid pregnancy or breastfeeding. Men and women of reproductive-age should use effective birth control during the treatment and for at least two weeks after your last dose. Patients should report any signs or symptoms of dehydration, such as dry mouth or decreased urination, to a healthcare provider immediately. It is advised to drink plenty of fluids while taking Afasted 30mg Tablet to stay hydrated, especially if you experience diarrhea as a side effect. When taking Afasted 30mg Tablet, stay away from grapefruit and grapefruit juice as they may interact with the medication and raise the risk of side effects.

References

  1. Boehringer Ingelheim Pharmaceuticals, Inc, US Food and Drug Administration, [ Revised on Jan 2018] [ Accessed on 16-02-2024 ], https://www.accessdata.fda.gov/drugsatfda_docs/label/2018/201292s014lbl.pdf
  2. Boehringer Ingelheim International GmbH, Electronic medicines compendium (emc), [ Revised on 21-06-2023 ] [ Accessed on 16-02-2024], https://www.medicines.org.uk/emc/files/pil.5147.pdf
  3. Boehringer Ingelheim pvt ltd, Therapeutic goods administration, [Revised on April 2014], [Accessed n 16-02-2024], https://www.tga.gov.au/sites/default/files/auspar-afatinib-dimaleate-140414.pdf
  4. Helga Wecker, Cornelius F Waller; Afatinib; Recent Results in Cancer Research 2018; https://pubmed.ncbi.nlm.nih.gov/30069769/

Safety Advice

Pregnancy: unsafe It is recommended to avoid this medication during pregnancy as Afasted 30mg Tablet is unsafe during pregnancy as it can cause fetal harm.

Lungs: Consult your doctor Afasted 30mg Tablet is primarily used to treat non-small cell lung cancer (NSCLC). Patients should consult healthcare providers if they have any other lung disease or history of lung inflammation before taking it.

Breastfeeding: unsafe It is unknown whether Afasted 30mg Tablet is excreted in human milk or not, and there are potential risks to a nursing infant. So it is not recommended for nursing women to take it.

Disclaimer

The information provided on this page is intended for general informational purposes only and should not be considered as medical advice. Always consult a qualified healthcare professional before starting, stopping, or changing any medication. Self-medication can be harmful. Med For Rare does not endorse self-diagnosis or self-treatment.

Written By: Muskan Patel, M.Pharm

Reviewed By: Dr. Vishwa Patel, MBBS