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Afatin 40mg Tablet
Salt Composition: AFATINIB DIMALEATE
- Manufacturer: BDR PHARMACEUTICALS INTERNATIONALS PVT LTD
- Pack Size: 28 TABLET(s) IN A BOTTLE
- Dosage Form: TABLET
- Strength: 40MG
- Prescription Required
- Storage: Afatin 40mg Tablet should be stored at room temperature, between 40°C to 25°C (68°F to 77°F). Protected from light. Keep it in its original packaging until it is ready to be used. Keep out of the reach of children and pets. Should be disposed of properly.
₹4725.00₹5906.25
Inclusive of all taxes
Product Introduction
Afatin 40mg Tablet is an anticancer medicine containing Afatinib dimaleate as its active ingredient. It is indicated for patients with non-small cell lung cancer (NSCLC) whose tumours carry certain non-resistant abnormal epidermal growth factor receptor (EGFR) gene mutations, and for patients with metastatic squamous NSCLC that has progressed following platinum-based chemotherapy. Cancer occurs when cells multiply abnormally and without normal growth controls. Before starting this medicine, inform your doctor if you have kidney disorders, breathing problems, liver disorders, heart problems, intolerance to sugars, severe dry eye, or other eye conditions. Afatin 40mg Tablet can slow disease progression and improve overall survival; it may also help patients maintain better quality of life over an extended period, including improved physical functioning, reduced pain, and better mental and emotional wellbeing. Inform your doctor if you wear contact lenses or are breastfeeding before taking this medication. Minimise sun exposure as this medicine may increase your skin's sensitivity to sunlight. This tablet is not recommended for children and adolescents below 18 years of age. Do not discontinue this medicine without consulting your doctor.
Uses
Afatin 40mg Tablet is indicated to treat the following conditions: Non-small cell lung cancer (NSCLC)
How it works
The therapeutic effect of Afatin 40mg Tablet is primarily related to its ability to inhibit the activity of certain proteins in cancer cells, specifically the epidermal growth factor receptor (EGFR) family of proteins. These proteins play a key role in promoting the growth and spread of cancer cells, and by inhibiting their activity, it can help to slow or stop the progression of cancer.
How to Use
Afatin 40mg Tablet is an oral medication that is usually taken once a day, at approximately the same time each day, with or without food. It should be taken as prescribed by a doctor. These capsules should be swallowed whole with a glass of water. They should not be crushed, chewed, or opened, as this can affect how the medication is absorbed and decrease its effectiveness. You should not take a double dose to make up for the second dose.
Side Effects
Like all medications, Afatin 40mg Tablet can cause side effects, although not everyone who takes it will experience them. Serious: Interstitial lung disease (ILD) Severe diarrhea or dehydration Liver problems Eye problems, such as corneal erosion or ulceration Hemorrhage or bleeding problems Kidney problems Cardiac problems Common: Diarrhea Mouth sores Acne or skin rash Nausea and vomiting Fatigue Loss of appetite Abdominal pain Nail changes, such as nail bed infections or inflammation Dry skin or itching Eye irritation or dryness Respiratory infections
Expert Tips
Follow all instructions and dosing recommendations provided by your healthcare provider. Do not take more or less of the medication than prescribed. Report any new or worsening symptoms to your healthcare provider immediately, especially if they relate to your lungs, eyes, skin, liver, kidneys, heart, or bleeding. Stay well-hydrated and report any signs or symptoms of dehydration to your healthcare provider immediately, especially if you experience severe diarrhea. Women should avoid pregnancy or breastfeeding. Reproductive-age women should use effective birth control during the treatment and for at least two weeks after your last dose. Patients should report any signs or symptoms of dehydration, such as dry mouth or decreased urination, to a healthcare provider immediately.
References
- Boehringer Ingelheim Pharmaceuticals, Inc, US Food and Drug Administration, [ Revised on Jan 2018] [ Accessed on 21st April 2023], https://www.accessdata.fda.gov/drugsatfda_docs/label/4018/401292s014lbl.pdf
- Boehringer Ingelheim International GmbH, Electronic medicines compendium (EMC), [ Revised on Sept 2020] [ Accessed on 21st April 2023], https://www.medicines.org.uk/emc/files/pil.5147.pdf
- Helga Wecker, Cornelius F Waller; Afatinib; Recent Results in Cancer Research 2018; https://pubmed.ncbi.nlm.nih.gov/40069769/
Safety Advice
Pregnancy: unsafe Afatin 40mg Tablet is unsafe during pregnancy as it can cause fetal harm. It is recommended to avoid this medication during pregnancy.
Lungs: Consult your doctor Afatin 40mg Tablet is primarily used to treat non-small cell lung cancer (NSCLC). Patients should consult healthcare providers if they have any other lung disease before taking it.
Breastfeeding: Consult your doctor It is unknown, whether Afatin 40mg Tablet is excreted in human milk or not, and the potential risks to a nursing infant are unknown. So nursing women should consult a healthcare provider before taking it.
Disclaimer
The information provided on this page is intended for general informational purposes only and should not be considered as medical advice. Always consult a qualified healthcare professional before starting, stopping, or changing any medication. Self-medication can be harmful. Med For Rare does not endorse self-diagnosis or self-treatment.