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Akynzeo Capsule

Salt Composition: NETUPITANT,PALONOSETRON

₹4500.00₹5625.00

Inclusive of all taxes

Akynzeo Capsule

Categories: Oncology

Conditions: Anti Cancer

Product Introduction

Akynzeo capsule contains the active ingredients Netupitant and Palonosetron. It is an antiemetic drug belonging to the class of 5-HT3 receptor antagonists. Akynzeo capsule is used in chemotherapy to prevent and treat nausea, vomiting, or sickness caused by cancer treatments such as chemotherapy, radiotherapy, or after surgery. Nausea is characterised by stomach discomfort and the urge to vomit. Patients with cancer can check the Akynzeo capsule 300mg/0.5mg price before purchase. Akynzeo capsule is available online in India from registered pharmacies. The Akynzeo 300mg/0.5mg capsule cost may vary depending on location and manufacturer. The prescribed Akynzeo capsule 300mg/0.5mg dosage is based on the patient's condition and type of chemotherapy. Akynzeo capsule containing Netupitant and Palonosetron is indicated particularly for highly emetogenic chemotherapy. Alternative formulations such as Akynzeo 300mg/0.5mg substitutes may also be available. Akynzeo capsule is manufactured in India by Glenmark Pharmaceuticals.

Uses

The Akynzeo Capsule Uses include: Postoperative nausea and vomiting. Chemotherapy-induced nausea and vomiting.

How it works

It is a type of serotonin receptor antagonist, which works by blocking the action of serotonin in the body that induces nausea and vomiting. The chemotherapeutic trigger zone(CTZ) contains the receptor serotonin, when this CTZ is stimulated, vomiting occurs. It prevents the signals from serotonin and helps to reduce the symptoms of nausea and vomiting.

How to Use

The medicine will be prescribed to you by a healthcare professional in a hospital setting. Akynzeo capsule is usually given about 30 minutes before you receive your anti-cancer medicine (chemotherapy) or right before anaesthesia for surgery. If you are taking Akynzeo hard capsules, it should be swallowed whole with a glass of water, with or without food, as directed by your healthcare provider.

Side Effects

Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them. Akynzeo capsule side effects are: Serious side effects of Akynzeo Capsule are: Hives Swollen face Breathing trouble Chest pain Common side effects of Akynzeo Capsule are: Headache Fatigue Dizziness Abdominal pain.

Expert Tips

Talk to your physician before taking Akynzeo capsule if you have: A history of repeated constipation Bowel blockage Heart problems Imbalance of certain minerals in your blood (e.g., potassium or magnesium) Inform your doctor or nurse if you are taking any medicines that affect your heartbeat, as these could cause heartbeat problems when taken with Akynzeo capsule.

References

  1. Accord Healthcare SLU, Electronic medicines compendium (emc), [Revised on Feb 2021] [ Accessed on 01st March 2023], https://www.medicines.org.uk/emc/files/pil.7235.pdf
  2. Fresenius kabi, US Food and Drug Administration, [Revised on Dec 2018] [Accessed on 01st March 2023], https://www.accessdata.fda.gov/drugsatfda_docs/label/2018/208109s001lbl.pdf
  3. Goodman & Gilman’s, The Pharmacological Basis of Therapeutics, Treatment of disorders of bowel motility and water flux, 12th edition, 2011, 1341.
  4. KD Tripathi, Essentials of Medical Pharmacology, Antiemetic, prokinetic and digestant drugs, 7th edition, 2013, 669.

Safety Advice

Pregnancy: Consult your doctor It is unknown whether Akynzeo capsule can be administered during pregnancy. Consult your doctor if you are pregnant or planning for pregnancy during the treatment.

Lungs: Consult your doctor It is not known whether Akynzeo capsule can be administered to patients with lung problems. Consult your doctor if you have any lung diseases before starting the treatment.

Breastfeeding: Consult your doctor It is not known if the Akynzeo capsule passes into your breast milk or if it will affect your baby or your breast milk. Please consult your doctor before breastfeeding.

Disclaimer

The information provided on this page is intended for general informational purposes only and should not be considered as medical advice. Always consult a qualified healthcare professional before starting, stopping, or changing any medication. Self-medication can be harmful. Med For Rare does not endorse self-diagnosis or self-treatment.

Written By: Muskan Patel, M.Pharm

Reviewed By: Dr. Vishwa Patel, MBBS