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Alkacel PGF 50mg Injection
Salt Composition: MELPHALAN
- Manufacturer: CELON LABORATORIES LTD
- Pack Size: 1 VIAL(s)
- Dosage Form: INJECTION
- Strength: 50MG
- Prescription Required
- Storage: Store in a refrigerator, 2° to 8°C Protect the medicine from light and excessive moisture. Keep the medicine out of reach of children and pets If you missed the dosing schedule, inform your healthcare professional immediately and reschedule.
₹1964.00₹3022.25
Inclusive of all taxes
Product Introduction
Alkacel PGF 50mg injection contains melphalan, an anticancer agent belonging to the class of alkylating agents. It is used to treat multiple myeloma, a cancer of the bone marrow. It is also indicated for advanced ovarian cancer, childhood neuroblastoma (cancer of the nervous system), malignant melanoma (skin cancer), and soft tissue sarcoma (cancer of muscle, fat, fibrous tissue, blood vessels, or other supporting tissues of the body). The medication works by reducing the number of abnormal cells your body produces.
Do not take Alkacel PGF 50mg injection if you are allergic to melphalan or any other ingredients in the formulation. Inform your physician if you have recently undergone radiotherapy or cancer chemotherapy, or if you have kidney problems. Do not take this medicine if you are pregnant or planning pregnancy. Inform your doctor if you have been vaccinated recently or are planning any vaccination.
Report to your physician immediately if you experience a rash, lumps or hives on the skin, swollen face, eyelids or lips, sudden wheeziness, or chest tightness after receiving this injection.
Uses
Multiple myeloma Advanced ovarian cancer Childhood neuroblastoma Malignant melanoma Soft tissue sarcoma
How it works
Alkacel PGF 50mg injection is an alkylating agent. It exerts its cytotoxic action primarily due to the cross-linking of strands of DNA and RNA, as well as the inhibition of protein synthesis. It works by stopping or slowing the growth of cancer cells in your body.
How to Use
Alkacel PGF 50mg injection will be administered to you by a doctor or other healthcare professional in a hospital setting trained in cancer chemotherapy. This injection can be given as an infusion into your vein, or it will be given as a perfusion to a particular part of your body through an artery. Your doctor will decide the dose, route of administration, and duration of the therapy based on your disease status, severity, and other factors such as body weight, other disease conditions, and age.
Side Effects
Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them. Common Decreased blood cell count Nausea, vomiting, diarrhea Mouth ulcers Hair loss Serious Cardiac arrest Liver inflammation Hypersensitivity skin reactions Acute renal failure Lung inflammation
Expert Tips
This medicine may cause changes in your blood levels. Your doctor may advise you to take certain blood tests during the treatment to monitor any unwanted side effects. Do not take an extra dose to make up for a missed dose. This medicine could cause infertility. Talk with your doctor before using this medicine if you are planning for pregnancy. This medicine may you to bleed, bruise, or get infections more easily. Take precautions to prevent illness and injury.
References
- Melphalan 50 mg Powder and Solvent for Solution for Injection/Infusion - Summary of Product Characteristics (SmPC) - (emc) [Internet]. www.medicines.org.uk. [revised on 2020] [cited 2023 Apr 7]. Available from: https://www.medicines.org.uk/emc/product/927/smpc
- HIGHLIGHTS OF PRESCRIBING INFORMATION - Melphalan injection [revised on 2017] [cited 2023 Apr 7]. Available from: https://www.accessdata.fda.gov/drugsatfda_docs/label/2017/207155s001lbl.pdf
- KD Tripathi, Essentials of Medical Pharmacology, Anticancer drugs, 7th edition, 2013, 860.
Safety Advice
Pregnancy: unsafe Do not take Alkacel PGF 50mg injection if you are pregnant because this may harm the unborn baby. Inform your physician if you are pregnant, suspecting pregnancy, or planning to get pregnant during the treatment. Use effective contraception during the treatment.
Lungs: Consult your doctor It is unknown whether Alkacel PGF 50mg injection can be used in patients with lung disorders. Consult your doctor if you have any lung diseases before starting the treatment.
Breastfeeding: unsafe Breastfeeding is not recommended in patients taking Alkacel PGF 50mg injection because the medicine passes into the breast milk in small amounts and may harm your baby. Do not breastfeed during the treatment.
Disclaimer
The information provided on this page is intended for general informational purposes only and should not be considered as medical advice. Always consult a qualified healthcare professional before starting, stopping, or changing any medication. Self-medication can be harmful. Med For Rare does not endorse self-diagnosis or self-treatment.