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Amfoeva 50mg Injection

Salt Composition: LIPOSOMAL AMPHOTERICIN B

₹2957.00₹3696.00

Inclusive of all taxes

Categories: Others

Conditions: Antifungal

Product Introduction

Amfoeva 50mg injection contains liposomal amphotericin B, an antifungal antibiotic. It is indicated for treatment of fungal infections affecting one or more deep body organs. It is also used to treat suspected fungal infections in patients presenting with elevated temperature and neutropenia (reduced white blood cell count). The medicine is also indicated for visceral leishmaniasis, a parasitic disease in certain populations.

Before starting your first course of treatment, your physician may administer a small test dose of Amfoeva 50mg injection to assess for allergic reactions. Do not use this injection if you are allergic to amphotericin B or any other ingredient in the medicine. Inform your physician if you experience a severe allergic reaction, have kidney or liver problems, or are undergoing dialysis. Advise your doctor if you have low potassium levels. This medicine contains sugar in each vial; inform your doctor if you have diabetes. Notify your physician if you are pregnant or breastfeeding before starting treatment.

The most common adverse effects reported with Amfoeva 50mg injection are skin rash, low potassium levels, diarrhoea, anaemia, insomnia, and shortness of breath. This medicine is not recommended for infants under 1 month of age.

Uses

Fungal infections of one or more deep organs of the body Suspected fungal infections Visceral leishmaniasis

How it works

Amfoeva 50mg injection binds primarily to ergosterol in sensitive fungi cell membranes, causing membrane permeability changes that result in leakage of intracellular contents and cell death.

How to Use

A doctor or nurse in a hospital or clinic setting will give it to you. It is given as an intravenous infusion drip (into your vein). Do not self-administer the injection. Your doctor will decide the dose and duration of the treatment based on your disease severity, body weight, and other factors.

Side Effects

Side effects are unwanted symptoms caused by medicines. Even though all drugs cause side effects, not everyone gets them. Common Skin rash Increased blood sugar levels Decreased potassium levels Diarrhea Nausea, vomiting Anemia Insomnia Shortness of breath Fever, chills or shivering Serious Cardia arrest GI bleeding Severe skin reactions Acute kidney injury

Expert Tips

This medicine may cause damage to the kidney. Inform your doctor if you have kidney problems. This injection may cause severe infusion reactions such as flushing, itching, sickness, swelling of the face, mouth, tongue and airways, difficulty breathing. Inform your physician immediately if you face any of these symptoms. It may be necessary to continue this medication for several weeks to several months in order to treat certain infections. Stopping the medication too early may result in a return of the infection.Tell your doctor if your condition lasts or gets worse.

References

  1. Goodman & Gilman’s, The Pharmacological Basis of Therapeutics, Chemotherapy of protozoal infections, 12th edition, 2011, 1424.
  2. KD Tripathi, Essentials of Medical Pharmacology, Antifungal drugs, 7th edition, 2013, 787-788.
  3. Gilead Sciences International Ltd, Electronic medicines compendium (emc), [ Revised on Sept 2020] [ Accessed on 11th June 2023], https://www.medicines.org.uk/emc/files/pil.1022.pdf
  4. Gilead Sciences, Inc, US Food and Drug Administration, [ Revised on Oct 2008] [ Accessed on 11th June 2023], https://www.accessdata.fda.gov/drugsatfda_docs/label/2008/050740s016lbl.pdf

Safety Advice

Pregnancy: Consult your doctor Inform your physician if you are pregnant, suspect pregnancy, or planning to become pregnant before receiving Amfoeva 50mg injection.

Lungs: Consult your doctor It is unknown whether Amfoeva 50mg injection can be used in patients with lung disorders. Consult your doctor if you have any lung diseases before starting the treatment.

Breastfeeding: Consult your doctor It is unknown whether Amfoeva 50mg injection is safe for breastfeeding women. Inform your physician if you are breastfeeding before initiating the treatment.

Disclaimer

The information provided on this page is intended for general informational purposes only and should not be considered as medical advice. Always consult a qualified healthcare professional before starting, stopping, or changing any medication. Self-medication can be harmful. Med For Rare does not endorse self-diagnosis or self-treatment.

Written By: Muskan Patel, M.Pharm

Reviewed By: Dr. Vishwa Patel, MBBS